Protein: | RRP5_YEAST |
Organism: | Saccharomyces cerevisiae S288c |
Length: | 1729 amino acids |
Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RRP5_YEAST.
Description | E-value | Query Range |
Subject Range |
|
0.0 | [1..1729] | [1..1729] |
|
0.0 | [2..1725] | [1..1689] |
|
0.0 | [4..1718] | [16..1832] |
|
0.0 | [35..1723] | [18..1772] |
|
0.0 | [700..1331] | [88..709] |
|
0.0 | [700..1331] | [65..686] |
|
0.0 | [700..1331] | [88..709] |
Region A: Residues: [1-69] |
1 11 21 31 41 51 | | | | | | 1 MVASTKRKRD EDFPLSREDS TKQPSTSSLV RNTEEVSFPR GGASALTPLE LKQVANEAAS 60 61 DVLFGNESV |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
MCM Score |
SCOP Match |
SCOP Description | ||
View | Download | 0.221 | a.144.1 | PABC (PABP) domain |
Term | Confidence | Notes |
structural constituent of ribosome | 5.1118741250402 | bayes_pls_golite062009 |
structural molecule activity | 4.51553901145182 | bayes_pls_golite062009 |
nuclease activity | 3.11657409772275 | bayes_pls_golite062009 |
3.02322635335914 | bayes_pls_golite062009 | |
ribonuclease activity | 2.66669472409706 | bayes_pls_golite062009 |
exoribonuclease activity | 2.4082195258205 | bayes_pls_golite062009 |
exoribonuclease activity, producing 5'-phosphomonoesters | 2.3619669410791 | bayes_pls_golite062009 |
RNA binding | 2.33019817554364 | bayes_pls_golite062009 |
3'-5'-exoribonuclease activity | 2.12039058720352 | bayes_pls_golite062009 |
exonuclease activity | 1.87925169250843 | bayes_pls_golite062009 |
endoribonuclease activity, producing 5'-phosphomonoesters | 1.74431545836806 | bayes_pls_golite062009 |
translation regulator activity | 1.66546288751201 | bayes_pls_golite062009 |
translation factor activity, nucleic acid binding | 1.61238850131825 | bayes_pls_golite062009 |
endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters | 1.59628511603826 | bayes_pls_golite062009 |
3'-5' exonuclease activity | 1.44123900197846 | bayes_pls_golite062009 |
translation initiation factor activity | 1.27539679024898 | bayes_pls_golite062009 |
catalytic activity | 1.25233849524628 | bayes_pls_golite062009 |
hydrolase activity, acting on ester bonds | 1.19753926150484 | bayes_pls_golite062009 |
nucleic acid binding | 1.12235348738959 | bayes_pls_golite062009 |
transcription regulator activity | 1.10433412699603 | bayes_pls_golite062009 |
aminoacyl-tRNA ligase activity | 1.07288786419238 | bayes_pls_golite062009 |
ligase activity, forming aminoacyl-tRNA and related compounds | 1.07285050275461 | bayes_pls_golite062009 |
ligase activity, forming carbon-oxygen bonds | 1.07285050275461 | bayes_pls_golite062009 |
excinuclease ABC activity | 1.05238432657007 | bayes_pls_golite062009 |
endonuclease activity | 0.991569665925888 | bayes_pls_golite062009 |
damaged DNA binding | 0.95191912850966 | bayes_pls_golite062009 |
binding | 0.762139256580538 | bayes_pls_golite062009 |
DNA binding | 0.710663468386339 | bayes_pls_golite062009 |
translation elongation factor activity | 0.55678032558705 | bayes_pls_golite062009 |
exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters | 0.52627345520111 | bayes_pls_golite062009 |
DNA-directed RNA polymerase activity | 0.39251242706379 | bayes_pls_golite062009 |
RNA polymerase activity | 0.39251242706379 | bayes_pls_golite062009 |
transcription factor activity | 0.332903382446869 | bayes_pls_golite062009 |
sequence-specific DNA binding | 0.21650406007586 | bayes_pls_golite062009 |
ligase activity | 0.148928528645156 | bayes_pls_golite062009 |
mRNA binding | 0.10617671731447 | bayes_pls_golite062009 |
deoxyribonuclease activity | 0.07404631453071 | bayes_pls_golite062009 |
endoribonuclease activity | 0.016619833072142 | bayes_pls_golite062009 |
Region A: Residues: [70-231] |
1 11 21 31 41 51 | | | | | | 1 KASEPASRPL KKKKTTKKST SKDSEASSAN SDEARAGLIE HVNFKTLKNG SSLLGQISAI 60 61 TKQDLCITFT DGISGYVNLT HISEEFTSIL EDLDEDMDSD TDAADEKKSK VEDAEYESSD 120 121 DEDEKLDKSN ELPNLRRYFH IGQWLRCSVI KNTSLEPSTK KS |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
Term | Confidence | Notes |
structural constituent of ribosome | 5.22538452462352 | bayes_pls_golite062009 |
structural molecule activity | 4.65301390020308 | bayes_pls_golite062009 |
RNA binding | 3.36396086314433 | bayes_pls_golite062009 |
transcription regulator activity | 3.24341202600661 | bayes_pls_golite062009 |
3'-5'-exoribonuclease activity | 2.16830676862423 | bayes_pls_golite062009 |
exoribonuclease activity, producing 5'-phosphomonoesters | 1.94887328847363 | bayes_pls_golite062009 |
exoribonuclease activity | 1.90081280972069 | bayes_pls_golite062009 |
nucleic acid binding | 1.53286219413126 | bayes_pls_golite062009 |
1.49823328757628 | bayes_pls_golite062009 | |
binding | 1.38311294671926 | bayes_pls_golite062009 |
ribonuclease activity | 1.31550811238109 | bayes_pls_golite062009 |
translation initiation factor activity | 1.27539679024898 | bayes_pls_golite062009 |
aminoacyl-tRNA ligase activity | 1.07288786419238 | bayes_pls_golite062009 |
ligase activity, forming aminoacyl-tRNA and related compounds | 1.07285050275461 | bayes_pls_golite062009 |
ligase activity, forming carbon-oxygen bonds | 1.07285050275461 | bayes_pls_golite062009 |
transcription termination factor activity | 1.01993495617192 | bayes_pls_golite062009 |
DNA binding | 0.86484629764139 | bayes_pls_golite062009 |
mRNA binding | 0.650019633484614 | bayes_pls_golite062009 |
3'-5' exonuclease activity | 0.477960254167 | bayes_pls_golite062009 |
RNA polymerase activity | 0.39251242706379 | bayes_pls_golite062009 |
DNA-directed RNA polymerase activity | 0.39251242706379 | bayes_pls_golite062009 |
tRNA-specific ribonuclease activity | 0.383567539949931 | bayes_pls_golite062009 |
transcription factor activity | 0.298729064067577 | bayes_pls_golite062009 |
protein binding | 0.292595239533272 | bayes_pls_golite062009 |
transferase activity, transferring phosphorus-containing groups | 0.1757578095579 | bayes_pls_golite062009 |
ligase activity | 0.148928528645156 | bayes_pls_golite062009 |
catalytic activity | 0.10089766806364 | bayes_pls_golite062009 |
Region A: Residues: [232-295] |
1 11 21 31 41 51 | | | | | | 1 KKKRIELTIE PSSVNIYADE DLVKSTSIQC AVKSIEDHGA TLDVGLPGFT GFIAKKDFGN 60 61 FEKL |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
MCM Score |
GO Score |
GO Term |
SCOP Match |
SCOP Description | ||
View | Download | 0.816 | 0.658 | nucleolus | b.34.2 | SH3-domain |
View | Download | 0.728 | 0.658 | nucleolus | b.34.5 | Translation proteins SH3-like domain |
View | Download | 0.686 | 0.658 | nucleolus | g.41.7 | Aspartate carbamoyltransferase, Regulatory-chain, C-terminal domain |
View | Download | 0.673 | 0.658 | nucleolus | b.34.2 | SH3-domain |
View | Download | 0.628 | 0.658 | nucleolus | g.41.3 | Zinc beta-ribbon |
View | Download | 0.622 | 0.658 | nucleolus | b.34.2 | SH3-domain |
View | Download | 0.591 | 0.658 | nucleolus | b.34.2 | SH3-domain |
View | Download | 0.571 | 0.658 | nucleolus | a.60.12 | DNA polymerase beta-like, second domain |
View | Download | 0.569 | 0.658 | nucleolus | b.34.1 | C-terminal domain of transcriptional repressors |
View | Download | 0.559 | 0.658 | nucleolus | d.49.1 | Signal recognition particle alu RNA binding heterodimer, SRP9/14 |
View | Download | 0.519 | 0.658 | nucleolus | d.17.1 | Cystatin/monellin |
View | Download | 0.473 | 0.658 | nucleolus | b.24.1 | Hyaluronate lyase-like, C-terminal domain |
View | Download | 0.469 | 0.658 | nucleolus | c.47.1 | Thioredoxin-like |
View | Download | 0.443 | 0.658 | nucleolus | d.50.1 | dsRNA-binding domain-like |
View | Download | 0.423 | 0.658 | nucleolus | d.49.1 | Signal recognition particle alu RNA binding heterodimer, SRP9/14 |
View | Download | 0.385 | 0.658 | nucleolus | b.34.3 | Myosin S1 fragment, N-terminal domain |
View | Download | 0.366 | 0.658 | nucleolus | d.130.1 | S-adenosylmethionine synthetase |
View | Download | 0.363 | 0.658 | nucleolus | b.1.2 | Fibronectin type III |
View | Download | 0.302 | 0.658 | nucleolus | g.49.1 | Cysteine-rich domain |
View | Download | 0.296 | 0.658 | nucleolus | d.17.2 | Copper amine oxidase, domains 1 and 2 |
View | Download | 0.287 | 0.658 | nucleolus | d.17.5 | Uracil-DNA glycosylase inhibitor protein |
View | Download | 0.242 | 0.658 | nucleolus | b.34.7 | DNA-binding domain of retroviral integrase |
View | Download | 0.224 | 0.658 | nucleolus | b.55.1 | PH domain-like |
View | Download | 0.216 | 0.658 | nucleolus | b.34.11 | GW domain |
View | Download | 0.209 | 0.658 | nucleolus | a.56.1 | CO dehydrogenase ISP C-domain like |
View | Download | 0.204 | 0.658 | nucleolus | c.47.1 | Thioredoxin-like |
View | Download | 0.202 | 0.658 | nucleolus | d.31.1 | Cdc48 domain 2-like |
Term | Confidence | Notes |
binding | 2.12690485191789 | bayes_pls_golite062009 |
RNA binding | 2.0770703064779 | bayes_pls_golite062009 |
protein binding | 1.39668540998298 | bayes_pls_golite062009 |
transcription regulator activity | 1.26149030245805 | bayes_pls_golite062009 |
nucleic acid binding | 1.01193875360949 | bayes_pls_golite062009 |
DNA binding | 0.80346414607277 | bayes_pls_golite062009 |
transcription factor activity | 0.374364600772076 | bayes_pls_golite062009 |
signal sequence binding | 0.0529781042891342 | bayes_pls_golite062009 |
Region A: Residues: [296-454] |
1 11 21 31 41 51 | | | | | | 1 LPGAVFLGNI TKKSDRSIVV NTDFSDKKNK ITQISSIDAI IPGQIVDLLC ESITKNGIAG 60 61 KVFGLVSGVV NVSHLRTFSE EDLKHKFVIG SSIRCRIIAC LENKSGDKVL ILSNLPHILK 120 121 LEDALRSTEG LDAFPIGYTF ESCSIKGRDS EYLYLALDD |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
Region A: Residues: [455-550] |
1 11 21 31 41 51 | | | | | | 1 DRLGKVHSSR VGEIENSENL SSRVLGYSPV DDIYQLSTDP KYLKLKYLRT NDIPIGELLP 60 61 SCEITSVSSS GIELKIFNGQ FKASVPPLHI SDTRLV |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
MCM Score |
SCOP Match |
SCOP Description | ||
View | Download | 0.507 | b.71.1 | Glycosyl hydrolase domain |
View | Download | 0.414 | b.88.1 | Mss4-like |
View | Download | 0.461 | d.43.1 | Elongation factor Ts (EF-Ts), dimerisation domain |
View | Download | 0.667 | b.61.2 | Metalloprotease inhibitor |
View | Download | 0.412 | b.55.1 | PH domain-like |
View | Download | 0.385 | b.61.3 | D-aminopeptidase, middle and C-terminal domains |
View | Download | 0.361 | b.1.1 | Immunoglobulin |
View | Download | 0.356 | d.15.4 | 2Fe-2S ferredoxin-like |
View | Download | 0.335 | d.110.1 | Profilin (actin-binding protein) |
View | Download | 0.310 | b.1.18 | E set domains |
View | Download | 0.307 | b.1.1 | Immunoglobulin |
View | Download | 0.287 | d.39.1 | Dynein light chain 8 (DLC8) |
View | Download | 0.275 | b.61.4 | Quinohemoprotein amine dehydrogenase A chain, domain 3 |
View | Download | 0.270 | d.16.1 | FAD-linked reductases, C-terminal domain |
View | Download | 0.257 | b.60.1 | Lipocalins |
View | Download | 0.256 | g.35.1 | HIPIP (high potential iron protein) |
View | Download | 0.226 | d.17.6 | Archaeosine tRNA-guanine transglycosylase, C2 domain |
View | Download | 0.216 | g.35.1 | HIPIP (high potential iron protein) |
View | Download | 0.209 | b.34.2 | SH3-domain |
View | Download | 0.207 | b.9.1 | Neurophysin II |
View | Download | 0.205 | d.16.1 | FAD-linked reductases, C-terminal domain |
Region A: Residues: [551-689] |
1 11 21 31 41 51 | | | | | | 1 YPERKFKIGS KVKGRVISVN SRGNVHVTLK KSLVNIEDNE LPLVSTYENA KNIKEKNEKT 60 61 LATIQVFKPN GCIISFFGGL SGFLPNSEIS EVFVKRPEEH LRLGQTVIVK LLDVDADRRR 120 121 IIATCKVSNE QAAQQKDTI |
Detection Method: | ![]() |
Confidence: | 56.522879 |
Match: | 1sro__ |
Description: | S1 RNA-binding domain of polyribonucleotide phosphorylase, PNPase |
Matching Structure (courtesy of the PDB):![]() |
Region A: Residues: [690-785] |
1 11 21 31 41 51 | | | | | | 1 ENIVPGRTII TVHVIEKTKD SVIVEIPDVG LRGVIYVGHL SDSRIEQNRA QLKKLRIGTE 60 61 LTGLVIDKDT RTRVFNMSLK SSLIKDAKKE TLPLTY |
Region B: Residues: [858-880] |
1 11 21 31 41 51 | | | | | | 1 FLLSLKAPKV KEEKKKVESN IED |
Detection Method: | ![]() |
Confidence: | 75.30103 |
Match: | 1e3pA_ |
Description: | Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3; S1 RNA-binding domain of polyribonucleotide phosphorylase, PNPase; Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domains 1 and 4; Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 6; Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domains 2 and 5 |
Matching Structure (courtesy of the PDB):![]() |
Region A: Residues: [786-857] |
1 11 21 31 41 51 | | | | | | 1 DDVKDLNKDV PMHAYIKSIS DKGLFVAFNG KFIGLVLPSY AVDSRDIDIS KAFYINQSVT 60 61 VYLLRTDDKN QK |
Region B: Residues: [881-943] |
1 11 21 31 41 51 | | | | | | 1 PVDSSIKSWD DLSIGSIVKA KIKSVKKNQL NVILAANLHG RVDIAEVFDT YEEITDKKQP 60 61 LSN |
Detection Method: | ![]() |
Confidence: | 75.30103 |
Match: | 1e3pA_ |
Description: | Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3; S1 RNA-binding domain of polyribonucleotide phosphorylase, PNPase; Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domains 1 and 4; Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 6; Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domains 2 and 5 |
Matching Structure (courtesy of the PDB):![]() |
Region A: Residues: [944-966] |
1 11 21 31 41 51 | | | | | | 1 YKKDDVIKVK IIGNHDVKSH KFL |
Region B: Residues: [1097-1175] |
1 11 21 31 41 51 | | | | | | 1 KIAEKYVLLD LGNKVTGISF ITDALNDFSL TLKEAFEDKI NNVIPTTVLS VDEQNKKIEL 60 61 SLRPATAKTR SIKSHEDLK |
Detection Method: | ![]() |
Confidence: | 75.30103 |
Match: | 1e3pA_ |
Description: | Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3; S1 RNA-binding domain of polyribonucleotide phosphorylase, PNPase; Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domains 1 and 4; Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 6; Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domains 2 and 5 |
Matching Structure (courtesy of the PDB):![]() |
Region A: Residues: [967-1096] |
1 11 21 31 41 51 | | | | | | 1 PITHKISKAS VLELSMKPSE LKSKEVHTKS LEEINIGQEL TGFVNNSSGN HLWLTISPVL 60 61 KARISLLDLA DNDSNFSENI ESVFPLGSAL QVKVASIDRE HGFVNAIGKS HVDINMSTIK 120 121 VGDELPGRVL |
Region B: Residues: [1176-1369] |
1 11 21 31 41 51 | | | | | | 1 QGEIVDGIVK NVNDKGIFVY LSRKVEAFVP VSKLSDSYLK EWKKFYKPMQ YVLGKVVTCD 60 61 EDSRISLTLR ESEINGDLKV LKTYSDIKAG DVFEGTIKSV TDFGVFVKLD NTVNVTGLAH 120 121 ITEIADKKPE DLSALFGVGD RVKAIVLKTN PEKKQISLSL KASHFSKEAE LASTTTTTTT 180 181 VDQLEKEDED EVMA |
Detection Method: | ![]() |
Confidence: | 75.30103 |
Match: | 1e3pA_ |
Description: | Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3; S1 RNA-binding domain of polyribonucleotide phosphorylase, PNPase; Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domains 1 and 4; Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 6; Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domains 2 and 5 |
Matching Structure (courtesy of the PDB):![]() |
Region A: Residues: [1370-1528] |
1 11 21 31 41 51 | | | | | | 1 DAGFNDSDSE SDIGDQNTEV ADRKPETSSD GLSLSAGFDW TASILDQAQE EEESDQDQED 60 61 FTENKKHKHK RRKENVVQDK TIDINTRAPE SVADFERLLI GNPNSSVVWM NYMAFQLQLS 120 121 EIEKARELAE RALKTINFRE EAEKLNIWIA MLNLENTFG |
Detection Method: | ![]() |
Confidence: | 23.69897 |
Match: | 1fchA_ |
Description: | Peroxin pex5 (peroxisomal targeting signal 1 (PTS1) receptor) |
Matching Structure (courtesy of the PDB):![]() |
Region A: Residues: [1529-1596] |
1 11 21 31 41 51 | | | | | | 1 TEETLEEVFS RACQYMDSYT IHTKLLGIYE ISEKFDKAAE LFKATAKKFG GEKVSIWVSW 60 61 GDFLISHN |
Detection Method: | ![]() |
Confidence: | 23.69897 |
Match: | 1fchA_ |
Description: | Peroxin pex5 (peroxisomal targeting signal 1 (PTS1) receptor) |
Matching Structure (courtesy of the PDB):![]() |
Region A: Residues: [1597-1729] |
1 11 21 31 41 51 | | | | | | 1 EEQEARTILG NALKALPKRN HIEVVRKFAQ LEFAKGDPER GRSLFEGLVA DAPKRIDLWN 60 61 VYVDQEVKAK DKKKVEDLFE RIITKKITRK QAKFFFNKWL QFEESEGDEK TIEYVKAKAT 120 121 EYVASHESQK ADE |
Detection Method: | ![]() |
Confidence: | 23.69897 |
Match: | 1fchA_ |
Description: | Peroxin pex5 (peroxisomal targeting signal 1 (PTS1) receptor) |
Matching Structure (courtesy of the PDB):![]() |