YRC Public Data Repository - Protein Structure Prediction

Protein:	CWC16_YEAST
Organism:	Saccharomyces cerevisiae S288c
Length:	278 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CWC16_YEAST.

Description	E-value	Query Range	Subject Range
gi\|190409737 - gi\|190409737\|gb\|EDV13002.1\| 32.3 kDa protein in CWP1-MBR1 intergenic region [Saccharomyces cerevisia... YJU2 - Essential protein required for pre-mRNA splicing; associates transiently with the spliceosomal NTC (... gi\|207343551 - gi\|207343551\|gb\|EDZ70985.1\| YKL095Wp-like protein [Saccharomyces cerevisiae AWRI1631] CWC16_YEAST - Protein CWC16 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YJU2 PE=1 SV=1	1.0E-97	[1..278]	[1..278]
CC130_MOUSE - Coiled-coil domain-containing protein 130 OS=Mus musculus GN=Ccdc130 PE=2 SV=1	5.0E-74	[1..213]	[1..213]
CCDC130 - coiled-coil domain containing 130	1.0E-73	[1..214]	[1..214]
CE01697 - YJU2 protein status:Partially_confirmed UniProt:Q09651 protein_id:CAA87435.1	1.0E-63	[1..208]	[1..207]
gi\|15222627, gi\|... - gi\|62320731\|dbj\|BAD95398.1\| hypothetical protein [Arabidopsis thaliana], gi\|44681478\|gb\|AAS47679.1\| ...	1.0E-61	[1..208]	[4..209]

Back

Predicted Domain #1

Region A:
Residues: [1-212]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSERKAINKY YPPDYNPLEA EKLSRKMAKK LKTMNKSHAS IRLMTPFSMR CLECNEYIPK  60
   61 SRKFNGKKEL LKEKYLDSIK IYRLTISCPR CANSIAFRTD PGNSDYVMEV GGVRNYVPQK 120
  121 PNDDLNAKTA VESIDETLQR LVREKEMEQN EKMGIKEQAD DKMDLLEKRL AKIQQEQEDD 180
  181 EELENLRKKN LEMSQRAEMI NRSKHAQQEK AV

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted functions:

Term	Confidence	Notes
transcription regulator activity	2.74510263950241	bayes_pls_golite062009
DNA binding	2.44566855074341	bayes_pls_golite062009
binding	2.27558039325716	bayes_pls_golite062009
nucleic acid binding	2.24669580094588	bayes_pls_golite062009
transcription factor activity	1.9022303099625	bayes_pls_golite062009
sequence-specific DNA binding	0.911347670379084	bayes_pls_golite062009
RNA polymerase II transcription factor activity	0.839985608194026	bayes_pls_golite062009
transcription activator activity	0.685318320359585	bayes_pls_golite062009
protein binding	0.606784236996154	bayes_pls_golite062009
transcription factor binding	0.50605454225389	bayes_pls_golite062009
ligand-dependent nuclear receptor activity	0.296219659608347	bayes_pls_golite062009
catalytic activity	0.133319360419662	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [213-278]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TTDDLDNLVD QVFDNHRQRT NKPGNNNDEK RTPLFNPTST KGKIQKKSSV RTNPLGIVIK  60
   61 RGKSLK

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: