YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|47096276, gi\|...
Organism:	Listeria monocytogenes serotype 1/2a str. F6854
Length:	313 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|47096276, gi|....

Description	E-value	Query Range	Subject Range
gi\|22776498, gi\|... - gi\|23098273\|ref\|NP_691739.1\| zinc-binding oxidoreductase [Oceanobacillus iheyensis HTE831], gi\|22776...	305.0	[0..1]	[311..1]
gi\|254872340, gi... - gi\|254872340\|ref\|ZP_05245050.1\| oxidoreductase [Listeria monocytogenes FSL N1-017], gi\|153165909\|ref... gi\|254932112, gi... - gi\|254932112\|ref\|ZP_05265471.1\| oxidoreductase [Listeria monocytogenes HPB2262], gi\|153201241\|ref\|ZP... gi\|226223242, gi... - gi\|226223242\|ref\|YP_002757349.1\| oxidoreductase [Listeria monocytogenes Clip81459], gi\|225875704\|emb... gi\|254878604 - gi\|254878604\|ref\|ZP_05251314.1\| oxidoreductase [Listeria monocytogenes FSL J2-071] gi\|254853189 - gi\|254853189\|ref\|ZP_05242537.1\| oxidoreductase [Listeria monocytogenes FSL R2-503] gi\|47019893, gi\|... - gi\|47091574\|ref\|ZP_00229370.1\| alcohol dehydrogenase, zinc-dependent [Listeria monocytogenes str. 4b... gi\|217965291, gi... - gi\|217965291\|ref\|YP_002350969.1\| alcohol dehydrogenase, zinc-dependent [Listeria monocytogenes HCC23... gi\|46906858, gi\|... - gi\|46906858\|ref\|YP_013247.1\| alcohol dehydrogenase, zinc-dependent [Listeria monocytogenes str. 4b F...	302.0	[0..1]	[313..1]
gi\|16799697 - gi\|16799697\|ref\|NP_469965.1\| hypothetical protein lin0622 [Listeria innocua Clip11262] gi\|25282950, gi\|... - pir\|\|AF1510 oxidoreductase homolog lin0622 [imported] - Listeria innocua (strain Clip11262), gi\|1641...	300.0	[0..1]	[313..1]
gi\|75812768, gi\|... - gi\|75812768\|ref\|YP_320385.1\| zinc-containing alcohol dehydrogenase superfamily protein [Anabaena var...	295.0	[0..1]	[313..321]
gi\|29343688, gi\|... - gi\|29376225\|ref\|NP_815379.1\| oxidoreductase, zinc-binding [Enterococcus faecalis V583], gi\|29343688\|...	294.0	[0..1]	[313..1]
gi\|47564631, gi\|... - gi\|47564631\|ref\|ZP_00235676.1\| oxidoreductase, zinc-binding [Bacillus cereus G9241], gi\|47558783\|gb\|...	289.0	[0..1]	[311..1]
gi\|163862688, gi... - gi\|89209002\|ref\|ZP_01187473.1\| Zinc-containing alcohol dehydrogenase superfamily [Bacillus weihenste... gi\|229167436, gi... - gi\|229167436\|ref\|ZP_04295174.1\| Alcohol dehydrogenase zinc-binding domain protein [Bacillus cereus A...	289.0	[0..1]	[312..1]
gi\|110622401, gi... - gi\|147919259\|ref\|YP_687005.1\| NADPH:quinone reductase [uncultured methanogenic archaeon RC-I], gi\|11...	289.0	[0..1]	[312..1]
gi\|229601380, gi... - gi\|229601380\|ref\|YP_002867708.1\| oxidoreductase, zinc-binding dehydrogenase family [Bacillus anthrac... gi\|254738549 - gi\|254738549\|ref\|ZP_05196252.1\| oxidoreductase, zinc-binding dehydrogenase family protein [Bacillus ... gi\|254752867 - gi\|254752867\|ref\|ZP_05204903.1\| oxidoreductase, zinc-binding dehydrogenase family protein [Bacillus ... gi\|254759139 - gi\|254759139\|ref\|ZP_05211165.1\| oxidoreductase, zinc-binding dehydrogenase family protein [Bacillus ... gi\|21401433, gi\|... - gi\|65320790\|ref\|ZP_00393749.1\| COG0604: NADPH:quinone reductase and related Zn-dependent oxidoreduct... gi\|49186311, gi\|... - gi\|49186311\|ref\|YP_029563.1\| alcohol dehydrogenase, zinc-containing [Bacillus anthracis str. Sterne]... gi\|47503998, gi\|... - gi\|47528850\|ref\|YP_020199.1\| alcohol dehydrogenase, zinc-containing [Bacillus anthracis str. 'Ames A... gi\|30263461, gi\|... - gi\|30263461\|ref\|NP_845838.1\| alcohol dehydrogenase, zinc-containing [Bacillus anthracis str. Ames], ... gi\|165872349, gi... - gi\|165872349\|ref\|ZP_02216985.1\| oxidoreductase, zinc-binding dehydrogenase family [Bacillus anthraci... gi\|170708548, gi... - gi\|170708548\|ref\|ZP_02898989.1\| oxidoreductase, zinc-binding dehydrogenase family [Bacillus anthraci... gi\|167514952, gi... - gi\|167637445\|ref\|ZP_02395725.1\| oxidoreductase, zinc-binding dehydrogenase family [Bacillus anthraci... gi\|190564341, gi... - gi\|190565024\|ref\|ZP_03017945.1\| oxidoreductase, zinc-binding dehydrogenase family [Bacillus anthraci... gi\|172080588, gi... - gi\|177654623\|ref\|ZP_02936447.1\| oxidoreductase, zinc-binding dehydrogenase family [Bacillus anthraci... gi\|227813662, gi... - gi\|227813662\|ref\|YP_002813671.1\| oxidoreductase, zinc-binding dehydrogenase family [Bacillus anthrac...	287.0	[0..1]	[311..1]
gi\|49478983, gi\|... - gi\|49478983\|ref\|YP_037595.1\| alcohol dehydrogenase, zinc-containing [Bacillus thuringiensis serovar ...	287.0	[0..1]	[311..1]

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Predicted Domain #1

Region A:
Residues: [1-313]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKAVVIENYG GKEELKEKEV AMPKAGKNQV IVKEAATSIN PIDWKLREGY LKQMMDWEFP  60
   61 IILGWDVAGV ISEVGEGVTD WKVGDEVFAR PETTRFGTYA EYTAVDDHLL APLPEGISFD 120
  121 EAASIPLAGL TAWQALFDHA KLQKGEKVLI HAGAGGVGTL AIQLAKHAGA EVITTASAKN 180
  181 HELLKSLGAD QVIDYKEVNF KDVLSDIDVV FDTMGGQIET DSYDVLKEGT GRLVSIVGIS 240
  241 NEDRAKEKNV TATGIWLQPN GEQLKELGKL LANKTIKPIV GATFPFSEKG VFDAHALSET 300
  301 HHAVGKIVIS FNK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	64.0
Match:	1yb5A
Description:	Crystal structure of human Zeta-Crystallin with bound NADP
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
oxidoreductase activity	3.09625241707629	bayes_pls_golite062009
alcohol dehydrogenase (NAD) activity	2.94416173750168	bayes_pls_golite062009
alcohol dehydrogenase activity, zinc-dependent	2.26153457113968	bayes_pls_golite062009
catalytic activity	1.79741889688267	bayes_pls_golite062009
oxidoreductase activity, acting on CH-OH group of donors	1.65338499044318	bayes_pls_golite062009
DNA binding	1.61355789916908	bayes_pls_golite062009
transcription regulator activity	1.55390653047158	bayes_pls_golite062009
nucleic acid binding	1.48478425318425	bayes_pls_golite062009
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	1.47309297191111	bayes_pls_golite062009
fatty acid synthase activity	1.23679054027553	bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor	1.22416351603098	bayes_pls_golite062009
chaperone binding	1.19079350615542	bayes_pls_golite062009
binding	0.982999356179965	bayes_pls_golite062009
transcription factor activity	0.91090893050278	bayes_pls_golite062009
monovalent inorganic cation transmembrane transporter activity	0.905392379451071	bayes_pls_golite062009
transporter activity	0.793769336118517	bayes_pls_golite062009
structural molecule activity	0.75267483298133	bayes_pls_golite062009
ligase activity	0.742884668104576	bayes_pls_golite062009
transmembrane transporter activity	0.635891484075352	bayes_pls_golite062009
oxidoreductase activity, acting on the CH-CH group of donors	0.62461633437589	bayes_pls_golite062009
3-oxoacyl-[acyl-carrier-protein] reductase activity	0.604742541607263	bayes_pls_golite062009
substrate-specific transporter activity	0.555188550031886	bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH	0.51503848775098	bayes_pls_golite062009
protein binding	0.507836099271263	bayes_pls_golite062009
retinol dehydrogenase activity	0.48941662111046	bayes_pls_golite062009
NAD or NADH binding	0.44922383360529	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	0.410307505174239	bayes_pls_golite062009
coenzyme binding	0.35922330382799	bayes_pls_golite062009
ion transmembrane transporter activity	0.29802814097478	bayes_pls_golite062009
hydrogen ion transmembrane transporter activity	0.261132005311306	bayes_pls_golite062009
active transmembrane transporter activity	0.239024094835991	bayes_pls_golite062009
3-hydroxyacyl-CoA dehydrogenase activity	0.233238483713519	bayes_pls_golite062009
cation transmembrane transporter activity	0.212092278332619	bayes_pls_golite062009
nucleoside-triphosphatase activity	0.113340150368917	bayes_pls_golite062009
pyrophosphatase activity	0.0696058100530442	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides	0.0591634687578807	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	0.0560606007580392	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: