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View Structure Prediction Details

Protein: OTU6A_MOUSE
Organism: Mus musculus
Length: 290 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for OTU6A_MOUSE.

Description E-value Query
Range
Subject
Range
gi|109512056, gi... - gi|27706912|ref|XP_228584.1| PREDICTED: similar to HIN-6 protease [Rattus norvegicus], gi|109512056|...
277.0 [0..1] [290..1]
gi|109131091 - gi|109131091|ref|XP_001082689.1| PREDICTED: similar to HIN-6 protease [Macaca mulatta]
256.0 [0..1] [289..1]
OTUD6A - OTU domain containing 6A
253.0 [0..1] [290..1]
gi|57108027 - gi|57108027|ref|XP_544171.1| PREDICTED: similar to CG7857-PA [Canis familiaris]
241.0 [0..13] [274..115]
gi|76630286 - gi|76630286|ref|XP_874339.1| PREDICTED: similar to CG7857-PA [Bos taurus]
238.0 [0..1] [276..5]
OTU6B_MOUSE - OTU domain-containing protein 6B OS=Mus musculus GN=Otud6b PE=1 SV=1
235.0 [0..3] [276..7]

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Predicted Domain #1
Region A:
Residues: [1-139]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSDTEQELQR VIRRHYREKR ELQAHIQTLK ASVPKNDKGR RKQMLADISR LEAEMEQRHK  60
   61 QELEKFGENP DSSVDSVTAD LEKMNLENMP PRPPKAQKRR DRRAHQERRH QERMPAAQAE 120
  121 QLAANRREEE EKVAAILGA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 3.522879
Match: 2i1jA
Description: No description for 2i1jA was found.

Predicted Domain #2
Region A:
Residues: [140-290]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KNLEMKTIPA DGHCMYRAIQ DQLVFSVTIE SLRYRTAYYM RKHIDDFLPF FTEPEAGNFY  60
   61 TREDFLRYCD DIVHNASWGG QLELRALSHV LQTPIEVVQA NSPTIVIGEE YTRKPVTLVY 120
  121 LHYACDFGEH YNSVKPIEVA GAFGGMAPRL F

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 17.0
Match: 1tffA
Description: Structure of Otubain-2
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
peptidase activity 3.40148357876466 bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides 3.21949433847862 bayes_pls_golite062009
cysteine-type peptidase activity 2.71117522993364 bayes_pls_golite062009
hydrolase activity 2.29464693834116 bayes_pls_golite062009
endopeptidase activity 2.26699762664334 bayes_pls_golite062009
cysteine-type endopeptidase activity 1.95802900199539 bayes_pls_golite062009
catalytic activity 1.05972260874031 bayes_pls_golite062009
binding 0.586727415287325 bayes_pls_golite062009
small conjugating protein-specific protease activity 0.500110970732392 bayes_pls_golite062009
protein binding 0.130065210618838 bayes_pls_golite062009
ubiquitin-specific protease activity 0.0101379718864654 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle