| Protein: | nhr-64 |
| Organism: | Caenorhabditis elegans |
| Length: | 344 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for nhr-64.
| Description | E-value | Query Range |
Subject Range |
|
|
256.0 | [0..6] | [327..187] |
|
Region A: Residues: [1-85] |
1 11 21 31 41 51
| | | | | |
1 MTLEEKEEVS TSTSQSPQSS SFENVFCAIC GDRATGKHYG AMSCDGCKAK RNSCRKCRFD 60
61 VCLRKGMRRD AVQTERDRIR PANPL
|
| Detection Method: |  |
| Confidence: | 3.95 |
| Match: | 1a6yA |
| Description: | Orphan nuclear receptor reverb |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| transcription regulator activity | 3.84932768708444 | bayes_pls_golite062009 |
| DNA binding | 3.45124926204188 | bayes_pls_golite062009 |
| nucleic acid binding | 3.34875987514951 | bayes_pls_golite062009 |
| binding | 2.8684204787273 | bayes_pls_golite062009 |
| transcription activator activity | 2.7888666510808 | bayes_pls_golite062009 |
| transcription factor activity | 2.74592237402384 | bayes_pls_golite062009 |
| sequence-specific DNA binding | 2.5486735958299 | bayes_pls_golite062009 |
| general RNA polymerase II transcription factor activity | 2.41415369932937 | bayes_pls_golite062009 |
| protein binding | 2.35367391992524 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity | 2.23212813739998 | bayes_pls_golite062009 |
| transcription repressor activity | 1.83119162033863 | bayes_pls_golite062009 |
| transcription factor binding | 1.22761682002 | bayes_pls_golite062009 |
| ligand-dependent nuclear receptor activity | 1.1269808729848 | bayes_pls_golite062009 |
| specific RNA polymerase II transcription factor activity | 1.02819346233483 | bayes_pls_golite062009 |
| transporter activity | 0.777447304729872 | bayes_pls_golite062009 |
| structural constituent of ribosome | 0.548821113052527 | bayes_pls_golite062009 |
| transmembrane transporter activity | 0.51780579506502 | bayes_pls_golite062009 |
| transcription coactivator activity | 0.514152028118082 | bayes_pls_golite062009 |
| transcription cofactor activity | 0.449959641856445 | bayes_pls_golite062009 |
| structural molecule activity | 0.366127650337533 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 0.196227315276875 | bayes_pls_golite062009 |
| catalytic activity | 0.133319360419662 | bayes_pls_golite062009 |
| receptor activity | 0.0887087342257975 | bayes_pls_golite062009 |
|
Region A: Residues: [86-344] |
1 11 21 31 41 51
| | | | | |
1 SNGSNGGIVP DDPLLDTLIR AEASTRGLRT TVITKTAEAR KQATTNDVTD SMNQQLTLMV 60
61 EWAKVLEGFQ RVDNITQVAL LRHFSAQHLV MCAAFRSIHL SDAVWLTNET CLHKDSPKIP 120
121 DMNRVAERII DQVTNPMRSL HMNEIEYIAL KAIAFFDPLA KGITSESYSD VEEMRQRILE 180
181 SFERHVRYVS PYKDMPLRFA NLLLLLPPML AISRDLVEDV QLAKLFGLAS IDNLMLELML 240
241 PNEGKNTTDK TSPPIMCHQ
|
| Detection Method: | |
| Confidence: | 50.69897 |
| Match: | 1lbdA |
| Description: | LIGAND-BINDING DOMAIN OF THE HUMAN NUCLEAR RECEPTOR RXR-ALPHA |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| transcription regulator activity | 5.53061626347066 | bayes_pls_golite062009 |
| DNA binding | 4.92165988569962 | bayes_pls_golite062009 |
| nucleic acid binding | 4.78024150262074 | bayes_pls_golite062009 |
| transcription activator activity | 4.53302455129434 | bayes_pls_golite062009 |
| sequence-specific DNA binding | 4.11614358606713 | bayes_pls_golite062009 |
| transcription factor activity | 4.0914094580319 | bayes_pls_golite062009 |
| ligand-dependent nuclear receptor activity | 3.89763470197726 | bayes_pls_golite062009 |
| binding | 3.85318710398432 | bayes_pls_golite062009 |
| transcription repressor activity | 3.83878598697109 | bayes_pls_golite062009 |
| protein binding | 3.21524787168952 | bayes_pls_golite062009 |
| transcription activator binding | 2.98235973123409 | bayes_pls_golite062009 |
| transcription factor binding | 2.68044489404568 | bayes_pls_golite062009 |
| receptor activity | 2.62895787183554 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity | 2.38308182853979 | bayes_pls_golite062009 |
| steroid hormone receptor activity | 2.30195937604451 | bayes_pls_golite062009 |
| transcription coactivator activity | 2.27959329058894 | bayes_pls_golite062009 |
| molecular transducer activity | 2.04709877069886 | bayes_pls_golite062009 |
| signal transducer activity | 2.04709877069886 | bayes_pls_golite062009 |
| transcription cofactor activity | 1.73827483890179 | bayes_pls_golite062009 |
| nuclear hormone receptor binding | 1.60419100774741 | bayes_pls_golite062009 |
| retinoic acid receptor binding | 1.59968001933699 | bayes_pls_golite062009 |
| retinoid binding | 1.57244905045132 | bayes_pls_golite062009 |
| isoprenoid binding | 1.45798199211445 | bayes_pls_golite062009 |
| retinoid X receptor binding | 1.45560845709347 | bayes_pls_golite062009 |
| ecdysteroid hormone receptor activity | 1.42190666652857 | bayes_pls_golite062009 |
| specific RNA polymerase II transcription factor activity | 1.34794228300778 | bayes_pls_golite062009 |
| promoter binding | 1.28787959668198 | bayes_pls_golite062009 |
| palmitoyl-CoA hydrolase activity | 1.23181585568439 | bayes_pls_golite062009 |
| transcription corepressor activity | 0.995333369475571 | bayes_pls_golite062009 |
| hormone receptor binding | 0.95284349923679 | bayes_pls_golite062009 |
| retinoic acid receptor activity | 0.853869057774515 | bayes_pls_golite062009 |
| protein dimerization activity | 0.797229273848179 | bayes_pls_golite062009 |
| protein N-terminus binding | 0.57701453824007 | bayes_pls_golite062009 |
| thyroid hormone receptor activity | 0.49784404390361 | bayes_pls_golite062009 |
| structure-specific DNA binding | 0.47826452126899 | bayes_pls_golite062009 |
| lipid binding | 0.475303782949439 | bayes_pls_golite062009 |
| protein heterodimerization activity | 0.45265806678057 | bayes_pls_golite062009 |
| double-stranded DNA binding | 0.42652610679613 | bayes_pls_golite062009 |
| receptor binding | 0.418843034756825 | bayes_pls_golite062009 |
| ligand-regulated transcription factor activity | 0.202197503742221 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity, enhancer binding | 0.15737167800277 | bayes_pls_golite062009 |
| catalytic activity | 0.106902059021677 | bayes_pls_golite062009 |
