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View Structure Prediction Details

Protein: gi|168275726
Organism: synthetic construct
Length: 1214 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|168275726.

Description E-value Query
Range
Subject
Range
gi|109034690, gi... - gi|109034690|ref|XP_001094152.1| PREDICTED: similar to bromodomain and PHD finger-containing protein...
0.0 [1..1214] [1..1214]
BRPF1 - bromodomain and PHD finger containing, 1
0.0 [1..1214] [1..1214]
gi|73984715 - gi|73984715|ref|XP_861729.1| PREDICTED: similar to bromodomain and PHD finger-containing protein 1 i...
0.0 [1..1214] [1..1214]
gi|76648412, gi|... - gi|76648412|ref|XP_878072.1| PREDICTED: similar to bromodomain and PHD finger-containing protein 1 i...
0.0 [1..1214] [1..1213]
gi|74224125 - gi|74224125|dbj|BAE33691.1| unnamed protein product [Mus musculus]
0.0 [1..1214] [1..1247]

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Predicted Domain #1
Region A:
Residues: [1-116]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGVDFDVKTF CHNLRATKPP YECPVETCRK VYKSYSGIEY HLYHYDHDNP PPPQQTPLRK  60
   61 HKKKGRQSRP ANKQSPSPSE VSQSPGREVM SYAQAQRMVE VDLHGRVHRI SIFDNL

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 2.02
Match: 2ghfA
Description: No description for 2ghfA was found.

Predicted functions:

Term Confidence Notes
binding 2.56065593409893 bayes_pls_golite062009
DNA binding 2.12670364830465 bayes_pls_golite062009
nucleic acid binding 2.03166503403228 bayes_pls_golite062009
transcription regulator activity 1.89798946190385 bayes_pls_golite062009
transcription factor activity 1.25050641170057 bayes_pls_golite062009
RNA polymerase II transcription factor activity 0.983792216045634 bayes_pls_golite062009
protein binding 0.975412203442928 bayes_pls_golite062009
transcription activator activity 0.682903516955242 bayes_pls_golite062009
sequence-specific DNA binding 0.343953984757786 bayes_pls_golite062009
chromatin binding 0.187378781886193 bayes_pls_golite062009
transcription repressor activity 0.0838352585191493 bayes_pls_golite062009
transcription factor binding 0.059503646600688 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [117-260]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DVVSEDEEAP EEAPENGSNK ENTETPAATP KSGKHKNKEK RKDSNHHHHH NVSASTTPKL  60
   61 PEVVYRELEQ DTPDAPPRPT SYYRYIEKSA EELDEEVEYD MDEEDYIWLD IMNERRKTEG 120
  121 VSPIPQEIFE YLMDRLEKES YFES

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [261-454]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HNKGDPNALV DEDAVCCICN DGECQNSNVI LFCDMCNLAV HQECYGVPYI PEGQWLCRRC  60
   61 LQSPSRAVDC ALCPNKGGAF KQTDDGRWAH VVCALWIPEV CFANTVFLEP IDSIEHIPPA 120
  121 RWKLTCYICK QRGSGACIQC HKANCYTAFH VTCAQQAGLY MKMEPVRETG ANGTSFSVRK 180
  181 TAYCDIHTPP GSAR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 8.69897
Match: 2ysmA
Description: No description for 2ysmA was found.

Predicted Domain #4
Region A:
Residues: [455-624]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RLPALSHSEG EEDEDEEEDE GKGWSSEKVK KAKAKSRIKM KKARKILAEK RAAAPVVSVP  60
   61 CIPPHRLSKI TNRLTIQRKS QFMQRLHSYW TLKRQSRNGV PLLRRLQTHL QSQRNCDQVG 120
  121 RDSEDKNWAL KEQLKSWQRL RHDLERARLL VELIRKREKL KRETIKVQQI 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [625-752]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AMEMQLTPFL ILLRKTLEQL QEKDTGNIFS EPVPLSEVPD YLDHIKKPMD FFTMKQNLEA  60
   61 YRYLNFDDFE EDFNLIVSNC LKYNAKDTIF YRAAVRLREQ GGAVLRQARR QAEKMGIDFE 120
  121 TGMHIPHS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 25.045757
Match: 2d9eA
Description: No description for 2d9eA was found.

Predicted Domain #6
Region A:
Residues: [753-873]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LAGDEATHHT EDAAEEERLV LLENQKHLPV EEQLKLLLER LDEVNASKQS VGRSRRAKMI  60
   61 KKEMTALRRK LAHQRETGRD GPERHGPSSR GSLTPHPAAC DKDGQTDSAA EESSSQETSK 120
  121 G

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #7
Region A:
Residues: [874-1076]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LGPNMSSTPA HEVGRRTSVL FSKKNPKTAG PPKRPGRPPK NRESQMTPSH GGSPVGPPQL  60
   61 PIMSSLRQRK RGRSPRPSSS SDSDSDKSTE DPPMDLPANG FSGGNQPVKK SFLVYRNDCS 120
  121 LPRSSSDSES SSSSSSSAAS DRTSTTPSKQ GRGKPSFSRG TFPEDSSEDT SGTENEAYSV 180
  181 GTGRGVGHSM VRKSLGRGAG WLS

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #8
Region A:
Residues: [1077-1214]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EDEDSPLDAL DLVWAKCRGY PSYPALIIDP KMPREGMFHH GVPIPVPPLE VLKLGEQMTQ  60
   61 EAREHLYLVL FFDNKRTWQW LPRTKLVPLG VNQDLDKEKM LEGRKSNIRK SVQIAYHRAL 120
  121 QHRSKVQGEQ SSETSDSD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 19.522879
Match: 2gfuA
Description: No description for 2gfuA was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle