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View Structure Prediction Details

Protein: gi|168275726
Organism: synthetic construct
Length: 1214 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|168275726.

Description E-value Query
Range
Subject
Range
gi|109034690, gi... - gi|109034690|ref|XP_001094152.1| PREDICTED: similar to bromodomain and PHD finger-containing protein...
0.0 [1..1214] [1..1214]
BRPF1 - bromodomain and PHD finger containing, 1
0.0 [1..1214] [1..1214]
gi|73984715 - gi|73984715|ref|XP_861729.1| PREDICTED: similar to bromodomain and PHD finger-containing protein 1 i...
0.0 [1..1214] [1..1214]
gi|76648412, gi|... - gi|76648412|ref|XP_878072.1| PREDICTED: similar to bromodomain and PHD finger-containing protein 1 i...
0.0 [1..1214] [1..1213]
gi|74224125 - gi|74224125|dbj|BAE33691.1| unnamed protein product [Mus musculus]
0.0 [1..1214] [1..1247]

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Predicted Domain #1
Region A:
Residues: [1-116]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGVDFDVKTF CHNLRATKPP YECPVETCRK VYKSYSGIEY HLYHYDHDNP PPPQQTPLRK  60
   61 HKKKGRQSRP ANKQSPSPSE VSQSPGREVM SYAQAQRMVE VDLHGRVHRI SIFDNL

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 2.02
Match: 2ghfA
Description: No description for 2ghfA was found.

Predicted functions:

Term Confidence Notes
binding 2.56065593409893 bayes_pls_golite062009
DNA binding 2.12670364830465 bayes_pls_golite062009
nucleic acid binding 2.03166503403228 bayes_pls_golite062009
transcription regulator activity 1.89798946190385 bayes_pls_golite062009
transcription factor activity 1.25050641170057 bayes_pls_golite062009
RNA polymerase II transcription factor activity 0.983792216045634 bayes_pls_golite062009
protein binding 0.975412203442928 bayes_pls_golite062009
transcription activator activity 0.682903516955242 bayes_pls_golite062009
sequence-specific DNA binding 0.343953984757786 bayes_pls_golite062009
chromatin binding 0.187378781886193 bayes_pls_golite062009
transcription repressor activity 0.0838352585191493 bayes_pls_golite062009
transcription factor binding 0.059503646600688 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [117-260]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DVVSEDEEAP EEAPENGSNK ENTETPAATP KSGKHKNKEK RKDSNHHHHH NVSASTTPKL  60
   61 PEVVYRELEQ DTPDAPPRPT SYYRYIEKSA EELDEEVEYD MDEEDYIWLD IMNERRKTEG 120
  121 VSPIPQEIFE YLMDRLEKES YFES

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.369 a.74.1 Cyclin-like
View Download 0.229 a.52.1 Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin
View Download 0.202 a.61.1 Retroviral matrix proteins
View Download 0.309 c.120.1 PIN domain-like

Predicted Domain #3
Region A:
Residues: [261-454]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HNKGDPNALV DEDAVCCICN DGECQNSNVI LFCDMCNLAV HQECYGVPYI PEGQWLCRRC  60
   61 LQSPSRAVDC ALCPNKGGAF KQTDDGRWAH VVCALWIPEV CFANTVFLEP IDSIEHIPPA 120
  121 RWKLTCYICK QRGSGACIQC HKANCYTAFH VTCAQQAGLY MKMEPVRETG ANGTSFSVRK 180
  181 TAYCDIHTPP GSAR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 8.69897
Match: 2ysmA
Description: No description for 2ysmA was found.

Predicted Domain #4
Region A:
Residues: [455-624]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RLPALSHSEG EEDEDEEEDE GKGWSSEKVK KAKAKSRIKM KKARKILAEK RAAAPVVSVP  60
   61 CIPPHRLSKI TNRLTIQRKS QFMQRLHSYW TLKRQSRNGV PLLRRLQTHL QSQRNCDQVG 120
  121 RDSEDKNWAL KEQLKSWQRL RHDLERARLL VELIRKREKL KRETIKVQQI 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [625-752]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AMEMQLTPFL ILLRKTLEQL QEKDTGNIFS EPVPLSEVPD YLDHIKKPMD FFTMKQNLEA  60
   61 YRYLNFDDFE EDFNLIVSNC LKYNAKDTIF YRAAVRLREQ GGAVLRQARR QAEKMGIDFE 120
  121 TGMHIPHS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 25.045757
Match: 2d9eA
Description: No description for 2d9eA was found.

Predicted Domain #6
Region A:
Residues: [753-873]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LAGDEATHHT EDAAEEERLV LLENQKHLPV EEQLKLLLER LDEVNASKQS VGRSRRAKMI  60
   61 KKEMTALRRK LAHQRETGRD GPERHGPSSR GSLTPHPAAC DKDGQTDSAA EESSSQETSK 120
  121 G

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #7
Region A:
Residues: [874-1076]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LGPNMSSTPA HEVGRRTSVL FSKKNPKTAG PPKRPGRPPK NRESQMTPSH GGSPVGPPQL  60
   61 PIMSSLRQRK RGRSPRPSSS SDSDSDKSTE DPPMDLPANG FSGGNQPVKK SFLVYRNDCS 120
  121 LPRSSSDSES SSSSSSSAAS DRTSTTPSKQ GRGKPSFSRG TFPEDSSEDT SGTENEAYSV 180
  181 GTGRGVGHSM VRKSLGRGAG WLS

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #8
Region A:
Residues: [1077-1214]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EDEDSPLDAL DLVWAKCRGY PSYPALIIDP KMPREGMFHH GVPIPVPPLE VLKLGEQMTQ  60
   61 EAREHLYLVL FFDNKRTWQW LPRTKLVPLG VNQDLDKEKM LEGRKSNIRK SVQIAYHRAL 120
  121 QHRSKVQGEQ SSETSDSD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 19.522879
Match: 2gfuA
Description: No description for 2gfuA was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle