YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|221324257
Organism:	Bacillus subtilis subsp. subtilis str. SMY
Length:	428 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|221324257.

Description	E-value	Query Range	Subject Range
gi\|226224138, gi... - gi\|226224138\|ref\|YP_002758245.1\| hypothetical protein Lm4b_01547 [Listeria monocytogenes Clip81459],... gi\|224499802 - gi\|224499802\|ref\|ZP_03668151.1\| GTPase ObgE [Listeria monocytogenes Finland 1988] gi\|224501523 - gi\|224501523\|ref\|ZP_03669830.1\| GTPase ObgE [Listeria monocytogenes FSL R2-561] gi\|126943540, gi... - gi\|254898297\|ref\|ZP_05258221.1\| GTPase ObgE [Listeria monocytogenes J0161], gi\|153183888\|ref\|ZP_0193... gi\|254829704, gi... - gi\|254829704\|ref\|ZP_05234359.1\| GTPase ObgE [Listeria monocytogenes 10403S], gi\|153196828\|ref\|ZP_019... gi\|153190975, gi... - gi\|254912211\|ref\|ZP_05262223.1\| GTPase ObgE [Listeria monocytogenes J2818], gi\|153190975\|ref\|ZP_0193... gi\|153166986, gi... - gi\|254873444\|ref\|ZP_05246154.1\| GTPase ObgE [Listeria monocytogenes FSL N1-017], gi\|153166986\|ref\|ZP... gi\|254828229, gi... - gi\|254828229\|ref\|ZP_05232916.1\| GTPase ObgE [Listeria monocytogenes FSL N3-165], gi\|153174696\|ref\|ZP... OBG_LISMF - GTPase Obg OS=Listeria monocytogenes serotype 4b (strain F2365) GN=obg PE=3 SV=1 gi\|254936539, gi... - gi\|254936539\|ref\|ZP_05268236.1\| GTPase ObgE [Listeria monocytogenes F6900], gi\|153179572\|ref\|ZP_0193... OBG_LISMO - GTPase Obg OS=Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e) GN=obg PE=3 SV=1 gi\|153202460, gi... - gi\|254931472\|ref\|ZP_05264831.1\| GTPase ObgE [Listeria monocytogenes HPB2262], gi\|153202460\|ref\|ZP_01... gi\|47097677, gi\|... - gi\|47097677\|ref\|ZP_00235191.1\| GTP-binding protein, GTP1/OBG family [Listeria monocytogenes str. 1/2... gi\|47017367, gi\|... - gi\|47094261\|ref\|ZP_00231970.1\| GTP-binding protein, GTP1/OBG family [Listeria monocytogenes str. 4b ... OBG_LISMO - GTPase obg OS=Listeria monocytogenes GN=obg PE=3 SV=1 gi\|255522334 - gi\|255522334\|ref\|ZP_05389571.1\| GTPase ObgE [Listeria monocytogenes FSL J1-175] gi\|254992893 - gi\|254992893\|ref\|ZP_05275083.1\| GTPase ObgE [Listeria monocytogenes FSL J2-064] gi\|254878974 - gi\|254878974\|ref\|ZP_05251684.1\| GTPase ObgE [Listeria monocytogenes FSL J2-071] gi\|254852161 - gi\|254852161\|ref\|ZP_05241509.1\| GTPase ObgE [Listeria monocytogenes FSL R2-503] gi\|254824404 - gi\|254824404\|ref\|ZP_05229405.1\| GTPase ObgE [Listeria monocytogenes FSL J1-194]	402.0	[0..1]	[428..1]

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Predicted Domain #1

Region A:
Residues: [1-341]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFVDQVKVYV KGGDGGNGMV AFRREKYVPK GGPAGGDGGK GGDVVFEVDE GLRTLMDFRY  60
   61 KKHFKAIRGE HGMSKNQHGR NADDMVIKVP PGTVVTDDDT KQVIADLTEH GQRAVIARGG 120
  121 RGGRGNSRFA TPANPAPQLS ENGEPGKERY IVLELKVLAD VGLVGFPSVG KSTLLSVVSS 180
  181 AKPKIADYHF TTLVPNLGMV ETDDGRSFVM ADLPGLIEGA HQGVGLGHQF LRHIERTRVI 240
  241 VHVIDMSGLE GRDPYDDYLT INQELSEYNL RLTERPQIIV ANKMDMPEAA ENLEAFKEKL 300
  301 TDDYPVFPIS AVTREGLREL LFEVANQLEN TPEFPLYDEE E

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	89.522879
Match:	1lnzA
Description:	Obg GTP-binding protein N-terminal domain; Obg GTP-binding protein C-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
GTPase activity	2.7209594329073	bayes_pls_golite062009
binding	2.21604035604783	bayes_pls_golite062009
catalytic activity	1.00104173493322	bayes_pls_golite062009
RNA helicase activity	0.94708387424268	bayes_pls_golite062009
ATP-dependent RNA helicase activity	0.93133090558732	bayes_pls_golite062009
RNA-dependent ATPase activity	0.91827876091109	bayes_pls_golite062009
nucleic acid binding	0.913322399315129	bayes_pls_golite062009
two-component response regulator activity	0.842299569386707	bayes_pls_golite062009
structural constituent of ribosome	0.738234102557832	bayes_pls_golite062009
purine nucleotide binding	0.569910969126728	bayes_pls_golite062009
purine ribonucleotide binding	0.568840867400671	bayes_pls_golite062009
ribonucleotide binding	0.568779924702229	bayes_pls_golite062009
nucleotide binding	0.564275755355315	bayes_pls_golite062009
molecular transducer activity	0.471461153565539	bayes_pls_golite062009
signal transducer activity	0.471461153565539	bayes_pls_golite062009
hydrolase activity	0.441914529351098	bayes_pls_golite062009
DNA binding	0.376487324624615	bayes_pls_golite062009
translation regulator activity	0.29096092258568	bayes_pls_golite062009
translation factor activity, nucleic acid binding	0.274994961137851	bayes_pls_golite062009
ATP binding	0.1860481660648	bayes_pls_golite062009
protein binding	0.170837278876362	bayes_pls_golite062009
adenyl ribonucleotide binding	0.152859582615242	bayes_pls_golite062009
transcription regulator activity	0.150159515184919	bayes_pls_golite062009
adenyl nucleotide binding	0.138615225841109	bayes_pls_golite062009
nucleoside-triphosphatase activity	0.0880086189831292	bayes_pls_golite062009
pyrophosphatase activity	0.0746809525189132	bayes_pls_golite062009
structural molecule activity	0.0558641287316701	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides	0.0557582578674931	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	0.0529869469040288	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [342-428]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LTQNRVMYTM ENEEVPFNIT RDPDGVFVLS GDSLERLFKM TDFSRDESVK RFARQMRGMG  60
   61 VDEALRERGA KDGDIIRLLE FEFEFID

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	46.221849
Match:	1jalA
Description:	YchF GTP-binding protein N-terminal domain; YchF GTP-binding protein, C-terminal domain
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: