YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|213427638
Organism:	Salmonella enterica subsp. enterica serovar Typhi str. E02-1180
Length:	951 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|213427638.

Description	E-value	Query Range	Subject Range
gi\|94415871, gi\|... - gi\|94415871\|ref\|ZP_01295706.1\| hypothetical protein PaerP_01002441 [Pseudomonas aeruginosa PA7], gi\|...	0.0	[1..951]	[1..950]
SYV_PSEAE - Valyl-tRNA synthetase OS=Pseudomonas aeruginosa GN=valS PE=3 SV=1 SYV_PSEAE - Valine--tRNA ligase OS=Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228) ...	0.0	[1..951]	[1..950]
SYV_SALCH - Valyl-tRNA synthetase OS=Salmonella choleraesuis GN=valS PE=3 SV=1 SYV_SALCH - Valine--tRNA ligase OS=Salmonella choleraesuis (strain SC-B67) GN=valS PE=3 SV=1 gi\|224470827, gi... - gi\|224586299\|ref\|YP_002640098.1\| valyl-tRNA synthetase [Salmonella enterica subsp. enterica serovar ... SYV_SALCH - Valine--tRNA ligase OS=Salmonella choleraesuis GN=valS PE=3 SV=1	0.0	[1..951]	[1..951]
gi\|107103354 - gi\|107103354\|ref\|ZP_01367272.1\| hypothetical protein PaerPA_01004423 [Pseudomonas aeruginosa PACS2]	0.0	[1..951]	[1..950]
SYV_YERPS - Valine--tRNA ligase OS=Yersinia pseudotuberculosis serotype I (strain IP32953) GN=valS PE=3 SV=1 gi\|153948685, gi... - gi\|77631524\|ref\|ZP_00794110.1\| COG0525: Valyl-tRNA synthetase [Yersinia pseudotuberculosis IP 31758]... SYV_YERPS - Valine--tRNA ligase OS=Yersinia pseudotuberculosis GN=valS PE=3 SV=1 gi\|186696917, gi... - gi\|186893891\|ref\|YP_001871003.1\| valyl-tRNA synthetase [Yersinia pseudotuberculosis PB1/+], gi\|18669...	0.0	[1..951]	[15..965]
gi\|238787641, gi... - gi\|77974071\|ref\|ZP_00829614.1\| COG0525: Valyl-tRNA synthetase [Yersinia frederiksenii ATCC 33641], g...	0.0	[1..951]	[15..965]
gi\|238714082, gi... - gi\|77957034\|ref\|ZP_00821102.1\| COG0525: Valyl-tRNA synthetase [Yersinia bercovieri ATCC 43970], gi\|2...	0.0	[1..951]	[15..965]
gi\|197096647, gi... - gi\|197365170\|ref\|YP_002144807.1\| valyl-tRNA synthetase [Salmonella enterica subsp. enterica serovar ... SYV_SALPA - Valine--tRNA ligase OS=Salmonella paratyphi A GN=valS PE=3 SV=1 SYV_SALPA - Valine--tRNA ligase OS=Salmonella paratyphi A (strain ATCC 9150 / SARB42) GN=valS PE=3 SV=1	0.0	[1..951]	[1..951]
gi\|116051862, gi... - gi\|32038982\|ref\|ZP_00137254.1\| COG0525: Valyl-tRNA synthetase [Pseudomonas aeruginosa UCBPP-PA14], g...	0.0	[1..951]	[1..950]
gi\|194547723, gi... - gi\|84319398\|ref\|ZP_00967795.1\| COG0525: Valyl-tRNA synthetase [Pseudomonas aeruginosa C3719], gi\|254...	0.0	[1..951]	[1..950]

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Predicted Domain #1

Region A:
Residues: [1-951]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEKTYNPQDI EQPLYEHWEK QGYFKPNGDE SKESFCIMIP PPNVTGSLHM GHAFQQTIMD  60
   61 TMIRYQRMQG KNTLWQVGTD HAGIATQMVV ERKIAAEEGK TRHDYGRDAF IDKIWQWKAE 120
  121 SGGTITRQMR RLGNSVDWER ERFTMDEGLS NAVKEVFVRL YKEDLIYRGK RLVNWDPKLR 180
  181 TAISDLEVEN RESKGSMWHI RYPLADGAKT ADGKDYLVVA TTRPETVLGD TGVAVNPEDP 240
  241 RYKDLIGKFV ILPLVNRRIP IVGDEHADME KGTGCVKITP AHDFNDYEVG KRHALPMINI 300
  301 LTFDGDIRES AEVFDTKGEE SNVYSSEIPA EFQKLERFAA RKAIVAAVDA LGLLEEIKPH 360
  361 DLTVPYGDRG GVVIEPMLTD QWYVRADVLA KPAVEAVENG DIQFVPKQYE NMYFSWMRDI 420
  421 QDWCISRQLW WGHRIPAWYD NDGNVYVGRT EDEVRQENNL GADVQLRQDE DVLDTWFSSA 480
  481 LWTFSTLGWP ENTDALRQFH PTSVMVSGFD IIFFWIARMI MMTMHFIKDE NGKPQVPFHT 540
  541 VYMTGLIRDD EGQKMSKSKG NVIDPLDMVD GISLPELLEK RTGNMMQPQM AEKIRKRTEK 600
  601 QFPNGIEPHG TDALRFTLAA LASTGRDINW DMKRLEGYRN FCNKLWNASR FVLMNTEEQD 660
  661 CGFNGGEMTL SLADRWILAE FNQTVKAYRE ALDNFRFDIA AGILYEFTWN QFCDWYLELT 720
  721 KPVMTGGSES ELRGTRHTLV TVLEGLLRLA HPIIPFITET IWQRVKVICG ITADTIMLQP 780
  781 FPEYNAAQVD EAALADTEWL KQAIVAVRNI RAEMNIAPGK PLELLLRGCS EEAVRRVNDN 840
  841 RSFLLNLARL ESITVLPADD KGPVSMTKII DGAELLIPMA GLINKEDELA RLAKEVAKIE 900
  901 GEIARIEGKL SNEGFVARAP EAVIAKEREK LDGYAEAKAK LIEQQAVISA L

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	1000.0
Match:	1gaxA
Description:	Valyl-tRNA synthetase (ValRS) C-terminal domain; Valyl-tRNA synthetase (ValRS)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
ligase activity, forming aminoacyl-tRNA and related compounds	8.24066297904343	bayes_pls_golite062009
ligase activity, forming carbon-oxygen bonds	8.24066297904343	bayes_pls_golite062009
aminoacyl-tRNA ligase activity	8.23006189348918	bayes_pls_golite062009
valine-tRNA ligase activity	7.13767629265822	bayes_pls_golite062009
leucine-tRNA ligase activity	7.03538514482698	bayes_pls_golite062009
ligase activity	6.98979325804867	bayes_pls_golite062009
isoleucine-tRNA ligase activity	6.38633897147986	bayes_pls_golite062009
methionine-tRNA ligase activity	2.56893064485672	bayes_pls_golite062009
catalytic activity	2.26766689929461	bayes_pls_golite062009
tyrosine-tRNA ligase activity	1.88984817882585	bayes_pls_golite062009
arginine-tRNA ligase activity	1.51931993626103	bayes_pls_golite062009
tryptophan-tRNA ligase activity	1.14187887833901	bayes_pls_golite062009
binding	0.987705174689351	bayes_pls_golite062009
cysteine-tRNA ligase activity	0.844943947059557	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	0.625793556381714	bayes_pls_golite062009
nucleic acid binding	0.514662028202085	bayes_pls_golite062009
nucleotidyltransferase activity	0.2293846471193	bayes_pls_golite062009
protein binding	0.143518788844143	bayes_pls_golite062009
glutamine-tRNA ligase activity	0.118292082006187	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: