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View Structure Prediction Details

Protein: gi|221315673
Organism: Bacillus subtilis subsp. subtilis str. NCIB 3610
Length: 340 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|221315673.

Description E-value Query
Range
Subject
Range
gi|25355521 - pir||B96987 probable transcription regulator [imported] - Clostridium acetobutylicum
gi|15893996, gi|... - gi|15893996|ref|NP_347345.1| putative transcriptional regulator [Clostridium acetobutylicum ATCC 824...
264.0 [0..1] [338..1]

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Predicted Domain #1
Region A:
Residues: [1-104]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNQLIQAQKK LLPDLLLVMQ KRFEILQYIR LTEPIGRRSL SASLGISERV LRGEVQFLKE  60
   61 QNLVDIKTNG MTLTEEGYEL LSVLEDTMKD VLGLTLLEKT LKER

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 5.522879
Match: 1i1gA
Description: LprA
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 3.98990675336286 bayes_pls_golite062009
DNA binding 3.4273272886116 bayes_pls_golite062009
nucleic acid binding 3.38054693035398 bayes_pls_golite062009
transcription factor activity 2.80110428028438 bayes_pls_golite062009
binding 2.18911933843505 bayes_pls_golite062009
transcription activator activity 0.53294679084865 bayes_pls_golite062009
sequence-specific DNA binding 0.53285802828572 bayes_pls_golite062009
transcription repressor activity 0.513853050429619 bayes_pls_golite062009
protein binding 0.035220363090062 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [105-340]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LNLKDAIIVS GDSDQSPWVK KEMGRAAVAC MKKRFSGKNI VAVTGGTTIE AVAEMMTPDS  60
   61 KNRELLFVPA RGGLGEDVKN QANTICAHMA EKASGTYRLL FVPGQLSQGA YSSIIEEPSV 120
  121 KEVLNTIKSA SMLVHGIGEA KTMAQRRNTP LEDLKKIDDN DAVTEAFGYY FNADGEVVHK 180
  181 VHSVGMQLDD IDAIPDIIAV AGGSSKAEAI EAYFKKPRNT VLVTDEGAAK KLLRDE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 41.39794
Match: 2okgA
Description: No description for 2okgA was found.

Predicted functions:

Term Confidence Notes
intramolecular oxidoreductase activity, interconverting aldoses and ketoses 2.23796402493477 bayes_pls_golite062009
ribose-5-phosphate isomerase activity 1.8706764549668 bayes_pls_golite062009
intramolecular oxidoreductase activity 1.76533950728927 bayes_pls_golite062009
catalytic activity 1.68776709414398 bayes_pls_golite062009
nucleic acid binding 0.965520574888216 bayes_pls_golite062009
transcription regulator activity 0.769423781192988 bayes_pls_golite062009
isomerase activity 0.61588631681492 bayes_pls_golite062009
DNA binding 0.223734115868557 bayes_pls_golite062009
6-phosphogluconolactonase activity 0.219352404564701 bayes_pls_golite062009
binding 0.199466104892993 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle