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View Structure Prediction Details

Protein: gi|157169143
Organism: Ruditapes philippinarum
Length: 136 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|157169143.

Description E-value Query
Range
Subject
Range
gi|88943485 - gi|88943485|ref|XP_497711.2| PREDICTED: similar to H3 histone, family 2 isoform 2 [Homo sapiens]
2.0E-65 [1..136] [45..180]
gi|76612880 - gi|76612880|ref|XP_871849.1| PREDICTED: similar to H3 histone, family 2 isoform 2 [Bos taurus]
4.0E-63 [1..136] [207..342]
gi|50728592 - gi|50728592|ref|XP_416193.1| PREDICTED: similar to histone protein Hist2h3c1 [Gallus gallus]
1.0E-62 [1..136] [621..756]
gi|74003971, gi|... - gi|74003975|ref|XP_859248.1| PREDICTED: similar to histone 1, H2ai (predicted) isoform 3 [Canis fami...
2.0E-61 [1..136] [1..136]
gi|148706930, gi... - gi|62739244|gb|AAH94041.1| Histone cluster 2, H3c1 [Mus musculus], gi|30061401|ref|NP_835734.1| hist...
9.0E-61 [1..136] [46..181]

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Predicted Domain #1
Region A:
Residues: [1-136]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MARTKQTARK STGGKAPRKQ LATKAARKSA PATGGVKKPH RYRPGTVALR EIRRYQKSTE  60
   61 LLIRKLPFQR LVREIAQDFK TDLRFQSSAV MALQEASEAY LVGLFEDTNL CAIHAKRVTI 120
  121 MPKDIQLARR IRGERA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 59.522879
Match: 1u35A
Description: Crystal structure of the nucleosome core particle containing the histone domain of macroH2A
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
general RNA polymerase II transcription factor activity 6.43582244485566 bayes_pls_golite062009
DNA binding 4.49118409263799 bayes_pls_golite062009
nucleic acid binding 4.35201412176948 bayes_pls_golite062009
transcription regulator activity 4.08606081850613 bayes_pls_golite062009
binding 3.27510691458843 bayes_pls_golite062009
centromeric DNA binding 2.60445660474495 bayes_pls_golite062009
transcription factor activity 2.51581622888695 bayes_pls_golite062009
RNA polymerase II transcription factor activity 2.38228606466152 bayes_pls_golite062009
transcription repressor activity 2.3574713307436 bayes_pls_golite062009
transcription initiation factor activity 1.57176056919918 bayes_pls_golite062009
lysine N-acetyltransferase activity 1.56792915081508 bayes_pls_golite062009
histone acetyltransferase activity 1.56792915081508 bayes_pls_golite062009
transcription corepressor activity 1.30859203490073 bayes_pls_golite062009
transcription activator activity 1.25487495162413 bayes_pls_golite062009
transcription factor binding 1.15204005455906 bayes_pls_golite062009
transcription coactivator activity 1.1297723528047 bayes_pls_golite062009
protein binding 1.07873333188144 bayes_pls_golite062009
transcription cofactor activity 1.01502031330902 bayes_pls_golite062009
histone binding 0.218942897869955 bayes_pls_golite062009
N-acetyltransferase activity 0.093732143600004 bayes_pls_golite062009
sequence-specific DNA binding 0.0852726470007639 bayes_pls_golite062009

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