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View Structure Prediction Details

Protein: gi|29726249, gi|...
Organism: Homo sapiens
Length: 125 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|29726249, gi|....

Description E-value Query
Range
Subject
Range
gi|19347603 - gi|19347603|gb|AAL25835.1| decay-accelerating factor 4ab [Homo sapiens]
165.0 [0..1] [125..32]
gi|114572305 - gi|114572305|ref|XP_001166792.1| PREDICTED: decay accelerating factor for complement isoform 8 [Pan ...
163.0 [0..1] [125..161]
gi|109018492 - gi|109018492|ref|XP_001111994.1| PREDICTED: similar to decay accelerating factor for complement isof...
161.0 [0..1] [125..162]

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Predicted Domain #1
Region A:
Residues: [1-125]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KSCPNPGEIR NGQIDVPGGI LFGATISFSC NTGYKLFGST SSFCLISGSS VQWSDPLPEC  60
   61 REIYCPAPPQ IDNGIIQGER DHYGYRQSVT YACNKGFTMI GEHSIYCTVN NDEGEWSGPP 120
  121 PECRG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 38.154902
Match: 2c8iE
Description: Complex Of Echovirus Type 12 With Domains 1, 2, 3 and 4 Of Its Receptor Decay Accelerating Factor (Cd55) By Cryo Electron Microscopy At 16 A
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
cell surface binding 4.33652203109712 bayes_pls_golite062009
complement binding 4.20610055582645 bayes_pls_golite062009
complement component C3b binding 4.08083046146348 bayes_pls_golite062009
eukaryotic cell surface binding 3.91640742116244 bayes_pls_golite062009
lipoprotein lipase activator activity 2.95441743480602 bayes_pls_golite062009
peptide antigen binding 2.75484182262813 bayes_pls_golite062009
interleukin-2 binding 2.71513067590075 bayes_pls_golite062009
antigen binding 2.37908978478817 bayes_pls_golite062009
binding 2.33940742543305 bayes_pls_golite062009
receptor activity 2.2622963118587 bayes_pls_golite062009
transmembrane receptor activity 2.20043691095891 bayes_pls_golite062009
interleukin-2 receptor activity 2.06172922937272 bayes_pls_golite062009
protein binding 1.97546801934296 bayes_pls_golite062009
signal transducer activity 1.96461646672141 bayes_pls_golite062009
molecular transducer activity 1.96461646672141 bayes_pls_golite062009
olfactory receptor activity 1.74347166869471 bayes_pls_golite062009
GABA receptor activity 1.69182753457619 bayes_pls_golite062009
glycoprotein binding 1.32101118463761 bayes_pls_golite062009
glycosaminoglycan binding 1.23968073093287 bayes_pls_golite062009
polysaccharide binding 1.17886521711108 bayes_pls_golite062009
growth factor binding 1.16513710870336 bayes_pls_golite062009
cytokine binding 1.15155354706712 bayes_pls_golite062009
pattern binding 1.12569810277318 bayes_pls_golite062009
opsonin binding 1.0527649340829 bayes_pls_golite062009
heparin binding 1.0223898285825 bayes_pls_golite062009
cytokine receptor activity 0.90184673014638 bayes_pls_golite062009
peptidase activity 0.594940121983039 bayes_pls_golite062009
hydrolase activity 0.540407885244421 bayes_pls_golite062009
lipase activator activity 0.35955770537116 bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides 0.308419080170741 bayes_pls_golite062009
GABA-B receptor activity 0.292458239230879 bayes_pls_golite062009
catalytic activity 0.252597265474331 bayes_pls_golite062009
carbohydrate binding 0.15682585610523 bayes_pls_golite062009

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