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View Structure Prediction Details

Protein: CYP59_ARATH
Organism: Arabidopsis thaliana
Length: 506 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CYP59_ARATH.

Description E-value Query
Range
Subject
Range
gi|16648909 - gi|16648909|gb|AAL24306.1| Unknown protein [Arabidopsis thaliana]
272.0 [0..1] [440..1]

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Predicted Domain #1
Region A:
Residues: [1-203]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSVLIVTSLG DIVIDLHSDK CPLTCKNFLK LCKIKYYNGC LFHTVQKDFT AQTGDPTGTG  60
   61 AGGDSIYKFL YGEQARFYKD EIHLDLKHSK TGTVAMASGG ENLNASQFYF TLRDDLDYLD 120
  121 GKHTVFGQIA EGFDTLTRIN EAYVDPKNRP YKNIRIKHTH ILDDPFDDPP QLAEMMPDAS 180
  181 PEGKPKEEVK DDVRLEDDWV PMD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 54.09691
Match: 1xyhA
Description: Crystal Structure of Recombinant Human Cyclophilin J
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
peptidyl-prolyl cis-trans isomerase activity 3.73853378771688 bayes_pls_golite062009
cis-trans isomerase activity 3.66963215732405 bayes_pls_golite062009
RNA binding 2.94609837984526 bayes_pls_golite062009
isomerase activity 1.96529188741504 bayes_pls_golite062009
binding 1.46018233647024 bayes_pls_golite062009
mRNA binding 1.45537055700871 bayes_pls_golite062009
unfolded protein binding 1.38124355054041 bayes_pls_golite062009
nucleic acid binding 0.939772862764466 bayes_pls_golite062009
catalytic activity 0.748655649755714 bayes_pls_golite062009
drug binding 0.36339132904137 bayes_pls_golite062009
protein binding 0.130251391659493 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [204-412]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EELGAQELEE VIREKAAHSS AVVLESIGDI PEAEVKPPDN VLFVCKLNPV TEDEDLHTIF  60
   61 SRFGTVVSAD VIRDFKTGDS LCYAFIEFEN KESCEQAYFK MDNALIDDRR IHVDFSQSVS 120
  121 KLWSQFRQKD SQKGKGNGCF KCGSTDHIAK DCVGGPSSKF IVKDQNRQHG GGEGYEMVFE 180
  181 GDVHETPKHN SHERERSEKI QRRSPHGNG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 7.154902
Match: 1l3kA
Description: Nuclear ribonucleoprotein A1 (RNP A1, UP1)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
RNA binding 6.73097473547076 bayes_pls_golite062009
6.62953239642182 bayes_pls_golite062009
mRNA binding 5.29759606920196 bayes_pls_golite062009
nucleic acid binding 3.81920018903278 bayes_pls_golite062009
snRNA binding 3.73900239153067 bayes_pls_golite062009
binding 3.44552682116509 bayes_pls_golite062009
poly-pyrimidine tract binding 3.11990160533699 bayes_pls_golite062009
single-stranded RNA binding 2.93798024346416 bayes_pls_golite062009
U1 snRNA binding 2.70790653818369 bayes_pls_golite062009
structural molecule activity 1.56454315220334 bayes_pls_golite062009
transcription regulator activity 1.07788694919471 bayes_pls_golite062009
protein binding 1.02232785292059 bayes_pls_golite062009
DNA binding 0.978604858165557 bayes_pls_golite062009
mRNA 3'-UTR binding 0.591700155096213 bayes_pls_golite062009
transporter activity 0.417047632648771 bayes_pls_golite062009
transmembrane transporter activity 0.288804044686487 bayes_pls_golite062009
transcription factor activity 0.234742017105535 bayes_pls_golite062009
general RNA polymerase II transcription factor activity 0.0532703224747206 bayes_pls_golite062009
nucleoside-triphosphatase activity 0.00171911393626201 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [413-506]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EGKRQHRDER DDGRRQHDRE DARELERKHR ERKERESRED EDRRRRRRRE ESRDKESRRE  60
   61 RDEDDHRSHR DYKERRRERD DRHGREARHE RRDR

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.03
Match: 2d57A
Description: Double layered 2D crystal structure of AQUAPORIN-4 (AQP4M23) at 3.2 a resolution by electron crystallography
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle