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View Structure Prediction Details

Protein: ID2_PONAB
Organism: Pongo abelii
Length: 134 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ID2_PONAB.

Description E-value Query
Range		 Subject
Range
ID2_RAT - DNA-binding protein inhibitor ID-2 OS=Rattus norvegicus GN=Id2 PE=1 SV=1
 1.0E-27 [1..134] [1..134]
ID2_MOUSE - DNA-binding protein inhibitor ID-2 OS=Mus musculus GN=Id2 PE=1 SV=3
 1.0E-27 [1..134] [1..134]
gi|61365342, gi|... - gi|61365342|gb|AAX42693.1| inhibitor of DNA binding 2 [synthetic construct], gi|60826047|gb|AAX36744...
 1.0E-27 [1..134] [1..134]
gi|3192887, gi|4... - gi|45384368|ref|NP_990333.1| inhibitor of DNA binding 2, dominant negative helix-loop-helix protein ...
 1.0E-27 [1..134] [1..134]
gi|42742051 - gi|42742051|gb|AAS45211.1| inhibitor of DNA binding 2 [Mesocricetus auratus]
 1.0E-27 [1..134] [1..134]
gi|62896923 - gi|62896923|dbj|BAD96402.1| inhibitor of DNA binding 2 variant [Homo sapiens]
 2.0E-27 [1..134] [1..134]
ID2_PIG - DNA-binding protein inhibitor ID-2 OS=Sus scrofa GN=ID2 PE=2 SV=1
 3.0E-27 [1..134] [1..134]
ID2_BOVIN - DNA-binding protein inhibitor ID-2 OS=Bos taurus GN=ID2 PE=2 SV=1
 4.0E-27 [1..134] [1..134]
gi|75708017 - gi|75708017|gb|ABA26458.1| Id2 [Coturnix japonica]
 5.0E-27 [1..134] [1..134]

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Predicted Domain #1
Region A:
Residues: [1-134] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKAFSPVRSV RKNSLSDHSL GISRSKTPVD DPMSLLYNMN DCYSKLKELV PSIPQNKKVS  60
   61 KMEILQHVID YILDLQIALD SHPTIVSLHH QRPGQNQASR TPLTTLNTDI SILSLQASEF 120
  121 PSELMSNDSK ALCG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 14.39794
Match: 1nkpA
Description: Myc prot-oncogene protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 5.38658950816179 bayes_pls_golite062009
DNA binding 5.18654839258297 bayes_pls_golite062009
nucleic acid binding 5.05768805749761 bayes_pls_golite062009
transcription factor activity 4.78039531631248 bayes_pls_golite062009
binding 3.81829206350975 bayes_pls_golite062009
RNA polymerase II transcription factor activity 3.39500382187264 bayes_pls_golite062009
protein binding 2.64975291677725 bayes_pls_golite062009
transcription factor binding 2.61163564741984 bayes_pls_golite062009
transcription repressor activity 2.58751248599889 bayes_pls_golite062009
transcription activator activity 2.5495467409976 bayes_pls_golite062009
RNA polymerase II transcription factor activity, enhancer binding 2.42306484786159 bayes_pls_golite062009
sequence-specific DNA binding 2.31910036997977 bayes_pls_golite062009
transcription corepressor activity 2.03674713048499 bayes_pls_golite062009
transcription cofactor activity 1.52770895937238 bayes_pls_golite062009
structure-specific DNA binding 1.07771706364343 bayes_pls_golite062009
double-stranded DNA binding 0.93846047598021 bayes_pls_golite062009
promoter binding 0.8576109846276 bayes_pls_golite062009
protein heterodimerization activity 0.53175615551166 bayes_pls_golite062009
transcription coactivator activity 0.3513586903977 bayes_pls_golite062009
protein dimerization activity 0.20674648626116 bayes_pls_golite062009
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