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View Structure Prediction Details

Protein: gi|52745937|emb|...
Organism: Rattus sp.
Length: 154 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|52745937|emb|....

Description E-value Query
Range
Subject
Range
gi|114666486 - gi|114666486|ref|XP_001174773.1| PREDICTED: similar to eukaryotic initiation factor 5A isoform I var...
6.0E-53 [1..154] [133..286]
gi|89031353 - gi|89031353|ref|XP_934040.1| PREDICTED: similar to eukaryotic translation initiation factor 5A [Homo...
2.0E-51 [1..154] [85..238]
gi|109113285 - gi|109113285|ref|XP_001118011.1| PREDICTED: similar to eukaryotic translation initiation factor 5A, ...
4.0E-50 [1..154] [37..190]
IF5A1_RABIT - Eukaryotic translation initiation factor 5A-1 OS=Oryctolagus cuniculus GN=EIF5A PE=1 SV=2
2.0E-49 [1..154] [1..154]

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Predicted Domain #1
Region A:
Residues: [1-154]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MADDLDFETG DAGASATFPM QCSALRKNGF VVLKGRPCKI VEMSTSKTGK HGHAKVHLVG  60
   61 IDIFTGKKYE DICPSTHNMD VPNIKRNDFQ LIGIQDGYLS LLQDSGEVRE DLRLPEGDLG 120
  121 KEIEQKYDCG EEILITVLSA MTEEAAVAIK AMAK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 38.0
Match: 1xtdA
Description: Structural Analysis of Leishmania mexicana eukaryotic initiation factor 5a
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
U6 snRNA binding 7.69488393698619 bayes_pls_golite062009
structural constituent of ribosome 6.60650180781768 bayes_pls_golite062009
structural molecule activity 6.0174879876147 bayes_pls_golite062009
translation initiation factor activity 5.09596850944863 bayes_pls_golite062009
nucleic acid binding 3.89165617439497 bayes_pls_golite062009
translation elongation factor activity 3.58178742491041 bayes_pls_golite062009
DNA binding 3.38561002225202 bayes_pls_golite062009
binding 2.83465364476231 bayes_pls_golite062009
RNA binding 1.76502371106766 bayes_pls_golite062009
sequence-specific DNA binding 1.74890841494748 bayes_pls_golite062009
transcription regulator activity 1.69669059514663 bayes_pls_golite062009
structure-specific DNA binding 1.54386990150255 bayes_pls_golite062009
translation regulator activity 1.46320772716954 bayes_pls_golite062009
translation factor activity, nucleic acid binding 1.40718318783582 bayes_pls_golite062009
single-stranded DNA binding 1.38349489974693 bayes_pls_golite062009
protein binding 1.20309946451799 bayes_pls_golite062009
transcription activator activity 0.990244702925461 bayes_pls_golite062009
mRNA binding 0.883475899526061 bayes_pls_golite062009
transcription factor activity 0.859071050218437 bayes_pls_golite062009
telomeric DNA binding 0.594907498313479 bayes_pls_golite062009
aminoacyl-tRNA ligase activity 0.474251377131502 bayes_pls_golite062009
ligase activity, forming carbon-oxygen bonds 0.47336621289748 bayes_pls_golite062009
ligase activity, forming aminoacyl-tRNA and related compounds 0.47336621289748 bayes_pls_golite062009
RNA polymerase activity 0.39251242706379 bayes_pls_golite062009
DNA-directed RNA polymerase activity 0.39251242706379 bayes_pls_golite062009
ribonuclease activity 0.35186207828037 bayes_pls_golite062009
nuclease activity 0.26446253803519 bayes_pls_golite062009

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