YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|7245729, gi\|7...
Organism:	Homo sapiens
Length:	277 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|7245729, gi|7....

Description	E-value	Query Range	Subject Range
gi\|157132324, gi... - gi\|157132324\|ref\|XP_001655999.1\| cathepsin l [Aedes aegypti], gi\|108881694\|gb\|EAT45919.1\| cathepsin ...	246.0	[0..1]	[266..87]
gi\|55740406 - gi\|55740406\|gb\|AAV63979.1\| cathepsin L1 precursor [Artemia parthenogenetica]	245.0	[0..1]	[266..91]
CEP2_ARATH - KDEL-tailed cysteine endopeptidase CEP2 OS=Arabidopsis thaliana GN=CEP2 PE=2 SV=1	245.0	[0..1]	[276..93]
gi\|55740402 - gi\|55740402\|gb\|AAV63977.1\| cathepsin L precursor [Artemia franciscana]	243.0	[0..1]	[266..91]
gi\|125811035, gi... - gi\|54636903\|gb\|EAL26306.1\| GA20520-PA [Drosophila pseudoobscura], gi\|125811035\|ref\|XP_001361728.1\| G...	241.0	[0..1]	[266..89]
gi\|47524507 - gi\|47524507\|gb\|AAT34987.1\| putative cysteine protease [Gossypium hirsutum]	239.0	[0..1]	[267..94]

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Predicted Domain #1

Region A:
Residues: [1-277]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FRRGQTCYRP LRGDGLAPLG RTTYPRPHEY LSPADLPKSW DWRNVDGVNY ASITRNQHIP  60
   61 QYCGSCWAHA STSAMADRIN IKRKGAWPST LLSVQNVIDC GNAGSCEGGN DLSVWDYAHQ 120
  121 HGIPDETCNN YQAKDQECDK FNQCGTCNEF KECHAIRNYT LWRVGDYGSL SGREKMMAEI 180
  181 YANGPISCGI MATERLANYT GGIYAEYQDT TYINHVVSVA GWGISDGTEY WIVRNSWGEP 240
  241 WGERGWLRIV TSTYKDGKGA RYNLAIEEHC TFGDPIV

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	60.522879
Match:	1deuA
Description:	(Pro)cathepsin X
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
peptidase activity	3.3849697474384	bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides	3.21949433847862	bayes_pls_golite062009
cysteine-type peptidase activity	2.71117522993364	bayes_pls_golite062009
hydrolase activity	2.29464693834116	bayes_pls_golite062009
endopeptidase activity	2.26699762664334	bayes_pls_golite062009
cysteine-type endopeptidase activity	1.95802900199539	bayes_pls_golite062009
catalytic activity	1.05972260874031	bayes_pls_golite062009
binding	0.797283672028226	bayes_pls_golite062009
small conjugating protein-specific protease activity	0.649171767629235	bayes_pls_golite062009
protein binding	0.130065210618838	bayes_pls_golite062009
ubiquitin-specific protease activity	0.0101379718864654	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: