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View Protein Complex Details

Complex Overview

From Publication: Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054
Notes: Classifier used Gene Ontology annotations. [FDR: 0.02] [SVM Score: 0.71915310255]
Complex Size: 2 proteins

Complex Member Proteins

Protein

 GO Cellular Component GO Biological Process GO Molecular Function
HOF1
  • cellular bud neck contractile ring
    		•
  • cytokinesis
  • response to DNA damage stimulus
    		•
  • cytoskeletal protein binding
    		•
    TPM1
  • cellular bud neck contractile ring
    		•
  • mitochondrion inheritance
  • vacuole inheritance
  • filamentous growth
  • budding cell isotropic bud growth
  • vesicle-mediated transport
  • intracellular mRNA localization
  • actin polymerization or depolymerization
  • pseudohyphal growth
  • actin filament organization
  • exocytosis
  • budding cell apical bud growth
    		•
  • actin lateral binding
    		•

    Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    cellular bud neck contractile ring 7.7306E-6 2 18 2 6292
    actomyosin contractile ring 7.7306E-6 2 18 2 6292
    contractile ring 7.7306E-6 2 18 2 6292
    cell division site 1.7735E-5 2 27 2 6292
    cell division site part 1.7735E-5 2 27 2 6292
    actin cytoskeleton 1.8038E-4 2 85 2 6292
    cell cortex part 2.304E-4 2 96 2 6292
    cell cortex 2.974E-4 2 109 2 6292
    cellular bud neck 4.1715E-4 2 129 2 6292
    cellular bud 6.9196E-4 2 166 2 6292
    site of polarized growth 7.0879E-4 2 168 2 6292
    cytoskeletal part 1.0156E-3 2 201 2 6292
    cytoskeleton 1.1732E-3 2 216 2 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    cell division 5.275E-4 2 145 2 6292
    budding cell isotropic bud growth 2.5415E-3 2 8 1 6292
    actin polymerization or depolymerization 2.859E-3 2 9 1 6292
    budding cell apical bud growth 3.1764E-3 2 10 1 6292
    intracellular mRNA localization 3.1764E-3 2 10 1 6292
    vacuole inheritance 4.7627E-3 2 15 1 6292
    mitochondrion inheritance 9.1975E-3 2 29 1 6292
    mitochondrion distribution 9.1975E-3 2 29 1 6292
    mitochondrion localization 9.5139E-3 2 30 1 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    cytoskeletal protein binding 8.6451E-5 2 59 2 6292
    actin lateral binding 6.3568E-4 2 2 1 6292
    actin filament binding 3.811E-3 2 12 1 6292
    actin binding 6.6645E-3 2 21 1 6292
    protein binding 9.4468E-3 2 612 2 6292
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle