YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Protein Complex Details

Complex Overview

From Publication: Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054
Notes: Classifier used Gene Ontology annotations. [FDR: 0.02] [SVM Score: 0.836003401176]
Complex Size: 2 proteins

Complex Member Proteins

Protein

 GO Cellular Component GO Biological Process GO Molecular Function
MRD1
  • nuclear outer membrane
  • nucleolus
    		•
  • endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • small-subunit processome assembly
  • endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • rRNA processing
    		•
  • snoRNA binding
  • rRNA primary transcript binding
    		•
    RRP3
  • nuclear outer membrane
  • nucleolus
    		•
  • ribosome biogenesis
    		•
  • ATP-dependent RNA helicase activity
    		•

    Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    nuclear outer membrane 1.8468E-4 2 86 2 6292
    nuclear membrane 2.3525E-4 2 97 2 6292
    outer membrane 7.9595E-4 2 178 2 6292
    organelle outer membrane 7.9595E-4 2 178 2 6292
    nuclear envelope 9.9543E-4 2 199 2 6292
    nucleolus 1.1194E-3 2 211 2 6292
    nuclear membrane-endoplasmic reticulum network 1.3539E-3 2 232 2 6292
    endomembrane system 3.9918E-3 2 398 2 6292
    nuclear lumen 5.1728E-3 2 453 2 6292
    envelope 6.43E-3 2 505 2 6292
    organelle envelope 6.43E-3 2 505 2 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    small-subunit processome assembly 3.1786E-4 2 1 1 6292
    ncRNA 5'-end processing 9.5344E-4 2 3 1 6292
    endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 9.5344E-4 2 3 1 6292
    endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 9.5344E-4 2 3 1 6292
    rRNA 5'-end processing 9.5344E-4 2 3 1 6292
    RNA 5'-end processing 9.5344E-4 2 3 1 6292
    maturation of 5.8S rRNA 1.2712E-3 2 4 1 6292
    cleavage involved in rRNA processing 1.2712E-3 2 4 1 6292
    maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 1.2712E-3 2 4 1 6292
    endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 1.2712E-3 2 4 1 6292
    endonucleolytic cleavage involved in rRNA processing 1.2712E-3 2 4 1 6292
    endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 1.2712E-3 2 4 1 6292
    ribosome biogenesis 3.0157E-3 2 346 2 6292
    ribonucleoprotein complex biogenesis 3.5243E-3 2 374 2 6292
    maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 4.1283E-3 2 13 1 6292
    ribosomal small subunit assembly 4.4455E-3 2 14 1 6292
    ribosomal small subunit biogenesis 8.248E-3 2 26 1 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    rRNA primary transcript binding 1.5888E-3 2 5 1 6292
    rRNA binding 5.0798E-3 2 16 1 6292
    ATP-dependent RNA helicase activity 8.8811E-3 2 28 1 6292
    RNA-dependent ATPase activity 9.1975E-3 2 29 1 6292
    snoRNA binding 9.8303E-3 2 31 1 6292
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle