






| From Publication: | Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054 |
| Notes: | Classifier used Gene Ontology annotations. [FDR: 0.02] [SVM Score: 0.92675623923] |
| Complex Size: | 2 proteins |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
| GO Term |
P-value |
A |
B |
I |
T |
| telomerase holoenzyme complex | 3.0316E-7 | 2 | 4 | 2 | 6292 |
| telomerase catalytic core complex | 3.1786E-4 | 2 | 1 | 1 | 6292 |
| nucleolus | 1.1194E-3 | 2 | 211 | 2 | 6292 |
| nuclear lumen | 5.1728E-3 | 2 | 453 | 2 | 6292 |
| ribonucleoprotein complex | 6.6615E-3 | 2 | 514 | 2 | 6292 |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
| GO Term |
P-value |
A |
B |
I |
T |
| telomere maintenance via telomere lengthening | 3.9411E-6 | 2 | 13 | 2 | 6292 |
| telomere maintenance via telomerase | 3.9411E-6 | 2 | 13 | 2 | 6292 |
| RNA-dependent DNA replication | 3.9411E-6 | 2 | 13 | 2 | 6292 |
| DNA replication | 3.791E-4 | 2 | 123 | 2 | 6292 |
| anatomical structure homeostasis | 2.0592E-3 | 2 | 286 | 2 | 6292 |
| telomere organization | 2.0592E-3 | 2 | 286 | 2 | 6292 |
| telomere maintenance | 2.0592E-3 | 2 | 286 | 2 | 6292 |
| homeostatic process | 4.1951E-3 | 2 | 408 | 2 | 6292 |
| regulation of biological quality | 7.6561E-3 | 2 | 551 | 2 | 6292 |
| chromosome organization | 7.7677E-3 | 2 | 555 | 2 | 6292 |
| DNA metabolic process | 8.631E-3 | 2 | 585 | 2 | 6292 |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
| GO Term |
P-value |
A |
B |
I |
T |
| telomerase activity | 3.0316E-7 | 2 | 4 | 2 | 6292 |
| RNA-directed DNA polymerase activity | 2.4511E-4 | 2 | 99 | 2 | 6292 |
| telomeric template RNA reverse transcriptase activity | 3.1786E-4 | 2 | 1 | 1 | 6292 |
| DNA polymerase activity | 3.312E-4 | 2 | 115 | 2 | 6292 |
| nucleotidyltransferase activity | 7.0879E-4 | 2 | 168 | 2 | 6292 |
| transferase activity, transferring phosphorus-containing groups | 4.4459E-3 | 2 | 420 | 2 | 6292 |
| single-stranded DNA binding | 5.0798E-3 | 2 | 16 | 1 | 6292 |