From Publication: | Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054 |
Notes: | Classifier used Gene Ontology annotations. [FDR: 0.02] [SVM Score: 0.975326511867] |
Complex Size: | 2 proteins |
Protein |
GO Cellular Component | GO Biological Process | GO Molecular Function |
MCM7 |
|
|
|
SLD3 |
|
|
|
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
nuclear chromosome part | 9.0721E-4 | 2 | 190 | 2 | 6292 |
nuclear chromosome | 1.3075E-3 | 2 | 228 | 2 | 6292 |
chromosomal part | 1.413E-3 | 2 | 237 | 2 | 6292 |
chromosome | 1.8898E-3 | 2 | 274 | 2 | 6292 |
MCM complex | 2.224E-3 | 2 | 7 | 1 | 6292 |
pre-replicative complex | 5.0798E-3 | 2 | 16 | 1 | 6292 |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
DNA unwinding involved in replication | 4.5979E-6 | 2 | 14 | 2 | 6292 |
DNA geometric change | 9.6001E-6 | 2 | 20 | 2 | 6292 |
DNA duplex unwinding | 9.6001E-6 | 2 | 20 | 2 | 6292 |
DNA replication initiation | 2.6678E-5 | 2 | 33 | 2 | 6292 |
DNA conformation change | 8.3521E-5 | 2 | 58 | 2 | 6292 |
DNA-dependent DNA replication | 1.678E-4 | 2 | 82 | 2 | 6292 |
DNA replication | 3.791E-4 | 2 | 123 | 2 | 6292 |
pre-replicative complex assembly | 4.1283E-3 | 2 | 13 | 1 | 6292 |
DNA metabolic process | 8.631E-3 | 2 | 585 | 2 | 6292 |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
chromatin binding | 2.6678E-5 | 2 | 33 | 2 | 6292 |
ATP-dependent DNA helicase activity | 5.7138E-3 | 2 | 18 | 1 | 6292 |
ATP binding | 7.6148E-3 | 2 | 24 | 1 | 6292 |
adenyl ribonucleotide binding | 7.9314E-3 | 2 | 25 | 1 | 6292 |
adenyl nucleotide binding | 9.5139E-3 | 2 | 30 | 1 | 6292 |
purine nucleoside binding | 9.8303E-3 | 2 | 31 | 1 | 6292 |