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View Protein Complex Details

Complex Overview

From Publication: Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054
Notes: Classifier used Gene Ontology annotations. [FDR: 0.02] [SVM Score: 0.984462140526]
Complex Size: 2 proteins

Complex Member Proteins

Cellular Component Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

spindle 1.9786E-4 2 89 2 6292
microtubule cytoskeleton 2.8118E-4 2 106 2 6292
cytoskeletal part 1.0156E-3 2 201 2 6292
cytoskeleton 1.1732E-3 2 216 2 6292
nuclear microtubule 1.9064E-3 2 6 1 6292
spindle midzone 2.224E-3 2 7 1 6292
DASH complex 3.811E-3 2 12 1 6292
microtubule 9.8303E-3 2 31 1 6292

Biological Process Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

regulation of microtubule polymerization or depolymerization 6.8716E-6 2 17 2 6292
regulation of microtubule-based process 6.8716E-6 2 17 2 6292
regulation of microtubule cytoskeleton organization 6.8716E-6 2 17 2 6292
microtubule polymerization or depolymerization 7.7306E-6 2 18 2 6292
regulation of cytoskeleton organization 9.6001E-6 2 20 2 6292
mitotic spindle organization in nucleus 1.6421E-5 2 26 2 6292
mitotic spindle organization 5.6994E-5 2 48 2 6292
spindle organization 5.9419E-5 2 49 2 6292
regulation of organelle organization 6.6999E-5 2 52 2 6292
regulation of cellular component organization 1.4021E-4 2 75 2 6292
microtubule cytoskeleton organization 2.3525E-4 2 97 2 6292
mitosis 2.7062E-4 2 104 2 6292
nuclear division 2.8118E-4 2 106 2 6292
microtubule-based process 3.0847E-4 2 111 2 6292
microtubule bundle formation 3.1786E-4 2 1 1 6292
organelle fission 3.1973E-4 2 113 2 6292
M phase of mitotic cell cycle 4.1068E-4 2 128 2 6292
spindle stabilization 6.3568E-4 2 2 1 6292
mitotic spindle stabilization 6.3568E-4 2 2 1 6292
regulation of spindle organization 6.3568E-4 2 2 1 6292
regulation of mitotic spindle organization 6.3568E-4 2 2 1 6292
cytoskeleton organization 1.3422E-3 2 231 2 6292
negative regulation of microtubule polymerization or depolymerization 1.5888E-3 2 5 1 6292
regulation of microtubule depolymerization 1.5888E-3 2 5 1 6292
negative regulation of microtubule depolymerization 1.5888E-3 2 5 1 6292
mitotic cell cycle 1.6363E-3 2 255 2 6292
microtubule depolymerization 1.9064E-3 2 6 1 6292
mitotic anaphase B 1.9064E-3 2 6 1 6292
M phase 2.1762E-3 2 294 2 6292
anaphase 2.224E-3 2 7 1 6292
negative regulation of protein complex disassembly 2.224E-3 2 7 1 6292
mitotic anaphase 2.224E-3 2 7 1 6292
negative regulation of cytoskeleton organization 2.5415E-3 2 8 1 6292
protein depolymerization 3.1764E-3 2 10 1 6292
regulation of protein complex disassembly 3.1764E-3 2 10 1 6292
cell cycle phase 3.5621E-3 2 376 2 6292
cell cycle process 6.0534E-3 2 490 2 6292
mitotic spindle elongation 6.6645E-3 2 21 1 6292
spindle elongation 6.6645E-3 2 21 1 6292
cell cycle 6.95E-3 2 525 2 6292
negative regulation of cellular component organization 9.1975E-3 2 29 1 6292
negative regulation of organelle organization 9.1975E-3 2 29 1 6292

Molecular Function Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

microtubule binding 3.1764E-3 2 10 1 6292
tubulin binding 6.3477E-3 2 20 1 6292
protein binding 9.4468E-3 2 612 2 6292

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle