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View Protein Complex Details

Complex Overview

From Publication: Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054
Notes: Classifier used Gene Ontology annotations. [FDR: 0.02] [SVM Score: 1.03334243954]
Complex Size: 2 proteins

Complex Member Proteins

Protein

 GO Cellular Component GO Biological Process GO Molecular Function
SSN8
  • transcription factor complex
    		•
  • negative regulation of transcription from RNA polymerase II promoter
  • telomere maintenance
  • meiosis
    		•
  • cyclin-dependent protein kinase regulator activity
  • general RNA polymerase II transcription factor activity
    		•
    TFB5
  • nucleus
  • holo TFIIH complex
    		•
  • DNA repair
  • nucleotide-excision repair
  • transcription initiation from RNA polymerase II promoter
    		•
  • general RNA polymerase II transcription factor activity
    		•

    Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    transcription factor complex 1.2556E-4 2 71 2 6292
    nucleoplasm part 1.5102E-3 2 245 2 6292
    nucleoplasm 1.7541E-3 2 264 2 6292
    holo TFIIH complex 3.1764E-3 2 10 1 6292
    nuclear lumen 5.1728E-3 2 453 2 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    transcription from RNA polymerase II promoter 2.8267E-3 2 335 2 6292
    transcription, DNA-dependent 6.3792E-3 2 503 2 6292
    RNA biosynthetic process 6.5067E-3 2 508 2 6292
    transcription 7.6839E-3 2 552 2 6292
    DNA metabolic process 8.631E-3 2 585 2 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    general RNA polymerase II transcription factor activity 1.0186E-4 2 64 2 6292
    RNA polymerase II transcription factor activity 4.2367E-4 2 130 2 6292
    transcription regulator activity 2.8947E-3 2 339 2 6292
    cyclin-dependent protein kinase regulator activity 8.248E-3 2 26 1 6292
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle