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View Protein Complex Details

Complex Overview

From Publication: Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054
Notes: Classifier used Gene Ontology annotations. [FDR: 0.02] [SVM Score: 1.31131708743]
Complex Size: 2 proteins

Complex Member Proteins

Protein

 GO Cellular Component GO Biological Process GO Molecular Function
RPB8
  • DNA-directed RNA polymerase I complex
  • DNA-directed RNA polymerase III complex
  • DNA-directed RNA polymerase II, core complex
    		•
  • transcription from RNA polymerase III promoter
  • transcription from RNA polymerase I promoter
  • transcription from RNA polymerase II promoter
    		•
  • DNA-directed RNA polymerase activity
    		•
    RPC34
  • nucleus
  • cytoplasm
  • mitochondrion
  • DNA-directed RNA polymerase III complex
    		•
  • transcription from RNA polymerase III promoter
  • ribosome biogenesis
    		•
  • DNA-directed RNA polymerase activity
    		•

    Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    DNA-directed RNA polymerase III complex 6.8716E-6 2 17 2 6292
    RNA polymerase complex 2.3495E-5 2 31 2 6292
    nuclear DNA-directed RNA polymerase complex 2.3495E-5 2 31 2 6292
    DNA-directed RNA polymerase complex 2.3495E-5 2 31 2 6292
    nucleoplasm part 1.5102E-3 2 245 2 6292
    nucleoplasm 1.7541E-3 2 264 2 6292
    DNA-directed RNA polymerase II, core complex 3.811E-3 2 12 1 6292
    DNA-directed RNA polymerase I complex 4.4455E-3 2 14 1 6292
    nuclear lumen 5.1728E-3 2 453 2 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    transcription from RNA polymerase III promoter 3.552E-5 2 38 2 6292
    transcription, DNA-dependent 6.3792E-3 2 503 2 6292
    RNA biosynthetic process 6.5067E-3 2 508 2 6292
    transcription 7.6839E-3 2 552 2 6292
    transcription from RNA polymerase I promoter 9.5139E-3 2 30 1 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    RNA polymerase activity 2.8346E-5 2 34 2 6292
    DNA-directed RNA polymerase activity 2.8346E-5 2 34 2 6292
    nucleotidyltransferase activity 7.0879E-4 2 168 2 6292
    transferase activity, transferring phosphorus-containing groups 4.4459E-3 2 420 2 6292
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle