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View Protein Complex Details

Complex Overview

From Publication: Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054
Notes: Classifier used Gene Ontology annotations. [FDR: 0.02] [SVM Score: 1.32796610538]
Complex Size: 2 proteins

Complex Member Proteins

Protein

 GO Cellular Component GO Biological Process GO Molecular Function
MMS2
  • nucleus
  • cytoplasm
  • ubiquitin conjugating enzyme complex
    		•
  • protein polyubiquitination
  • response to DNA damage stimulus
  • postreplication repair
    		•
  • ubiquitin-protein ligase activity
    		•
    UBC13
  • nucleus
  • cytoplasm
  • ubiquitin conjugating enzyme complex
    		•
  • protein polyubiquitination
  • protein monoubiquitination
  • postreplication repair
    		•
  • ubiquitin-protein ligase activity
    		•

    Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    ubiquitin conjugating enzyme complex 5.0527E-8 2 2 2 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    postreplication repair 7.7306E-6 2 18 2 6292
    protein polyubiquitination 1.0611E-5 2 21 2 6292
    protein ubiquitination 1.051E-4 2 65 2 6292
    protein modification by small protein conjugation 1.8468E-4 2 86 2 6292
    protein modification by small protein conjugation or removal 3.2544E-4 2 114 2 6292
    DNA repair 9.2646E-4 2 192 2 6292
    response to DNA damage stimulus 1.4011E-3 2 236 2 6292
    cellular response to stress 2.1173E-3 2 290 2 6292
    post-translational protein modification 3.2108E-3 2 357 2 6292
    cellular response to stimulus 3.6193E-3 2 379 2 6292
    response to stress 6.2277E-3 2 497 2 6292
    protein modification process 6.278E-3 2 499 2 6292
    protein monoubiquitination 7.2981E-3 2 23 1 6292
    macromolecule modification 8.1649E-3 2 569 2 6292
    DNA metabolic process 8.631E-3 2 585 2 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    ubiquitin-protein ligase activity 8.0641E-5 2 57 2 6292
    small conjugating protein ligase activity 9.5546E-5 2 62 2 6292
    acid-amino acid ligase activity 1.2556E-4 2 71 2 6292
    ligase activity, forming carbon-nitrogen bonds 2.2085E-4 2 94 2 6292
    ligase activity 5.6464E-4 2 150 2 6292
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle