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View Protein Complex Details

Complex Overview

From Publication: Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054
Notes: Classfier did not use Gene Ontology annotations. [FDR: 0.021] [SVM Score: 0.971100463022]
Complex Size: 2 proteins

Complex Member Proteins

Cellular Component Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

U4/U6 x U5 tri-snRNP complex 2.5061E-5 2 32 2 6292
small nuclear ribonucleoprotein complex 9.8679E-5 2 63 2 6292
ribonucleoprotein complex 6.6615E-3 2 514 2 6292

Biological Process Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

spliceosomal conformational changes to generate catalytic conformation 1.819E-6 2 9 2 6292
ribonucleoprotein complex assembly 2.1151E-4 2 92 2 6292
nuclear mRNA splicing, via spliceosome 2.4511E-4 2 99 2 6292
RNA splicing, via transesterification reactions with bulged adenosine as nucleophile 2.5011E-4 2 100 2 6292
RNA splicing, via transesterification reactions 2.8654E-4 2 107 2 6292
RNA splicing 4.3685E-4 2 132 2 6292
mRNA processing 6.1087E-4 2 156 2 6292
cellular macromolecular complex assembly 8.3223E-4 2 182 2 6292
generation of catalytic spliceosome for first transesterification step 9.5344E-4 2 3 1 6292
mRNA metabolic process 1.1408E-3 2 213 2 6292
generation of catalytic spliceosome for second transesterification step 1.5888E-3 2 5 1 6292
cellular macromolecular complex subunit organization 1.6882E-3 2 259 2 6292
macromolecular complex assembly 1.9877E-3 2 281 2 6292
macromolecular complex subunit organization 3.2108E-3 2 357 2 6292
ribonucleoprotein complex biogenesis 3.5243E-3 2 374 2 6292
RNA processing 3.6384E-3 2 380 2 6292
cellular component assembly 3.7349E-3 2 385 2 6292

Molecular Function Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

second spliceosomal transesterification activity 2.224E-3 2 7 1 6292

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle