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View Protein Complex Details

Complex Overview

From Publication: Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054
Notes: Classfier did not use Gene Ontology annotations. [FDR: 0.021] [SVM Score: 1.03262320889]
Complex Size: 2 proteins

Complex Member Proteins

Protein

 GO Cellular Component GO Biological Process GO Molecular Function
DAD3
  • DASH complex
  • spindle
  • kinetochore
    		•
  • mitotic spindle organization in nucleus
  • mitosis
  • regulation of microtubule polymerization or depolymerization
    		•
  • protein binding
    		•
    DAD4
  • DASH complex
  • spindle
  • kinetochore
    		•
  • mitotic spindle organization in nucleus
  • mitosis
  • regulation of microtubule polymerization or depolymerization
    		•
  • protein binding
    		•

    Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    DASH complex 3.3348E-6 2 12 2 6292
    condensed nuclear chromosome kinetochore 5.9419E-5 2 49 2 6292
    condensed chromosome kinetochore 5.9419E-5 2 49 2 6292
    condensed chromosome, centromeric region 7.5032E-5 2 55 2 6292
    condensed nuclear chromosome, centromeric region 7.5032E-5 2 55 2 6292
    kinetochore 8.9432E-5 2 60 2 6292
    chromosome, centromeric region 1.1171E-4 2 67 2 6292
    condensed nuclear chromosome 1.8468E-4 2 86 2 6292
    spindle 1.9786E-4 2 89 2 6292
    condensed chromosome 2.2085E-4 2 94 2 6292
    microtubule cytoskeleton 2.8118E-4 2 106 2 6292
    nuclear chromosome part 9.0721E-4 2 190 2 6292
    cytoskeletal part 1.0156E-3 2 201 2 6292
    cytoskeleton 1.1732E-3 2 216 2 6292
    nuclear chromosome 1.3075E-3 2 228 2 6292
    chromosomal part 1.413E-3 2 237 2 6292
    chromosome 1.8898E-3 2 274 2 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    regulation of microtubule cytoskeleton organization 6.8716E-6 2 17 2 6292
    regulation of microtubule polymerization or depolymerization 6.8716E-6 2 17 2 6292
    regulation of microtubule-based process 6.8716E-6 2 17 2 6292
    microtubule polymerization or depolymerization 7.7306E-6 2 18 2 6292
    regulation of cytoskeleton organization 9.6001E-6 2 20 2 6292
    mitotic spindle organization in nucleus 1.6421E-5 2 26 2 6292
    mitotic spindle organization 5.6994E-5 2 48 2 6292
    spindle organization 5.9419E-5 2 49 2 6292
    regulation of organelle organization 6.6999E-5 2 52 2 6292
    regulation of cellular component organization 1.4021E-4 2 75 2 6292
    microtubule cytoskeleton organization 2.3525E-4 2 97 2 6292
    mitosis 2.7062E-4 2 104 2 6292
    nuclear division 2.8118E-4 2 106 2 6292
    microtubule-based process 3.0847E-4 2 111 2 6292
    organelle fission 3.1973E-4 2 113 2 6292
    M phase of mitotic cell cycle 4.1068E-4 2 128 2 6292
    cytoskeleton organization 1.3422E-3 2 231 2 6292
    mitotic cell cycle 1.6363E-3 2 255 2 6292
    M phase 2.1762E-3 2 294 2 6292
    cell cycle phase 3.5621E-3 2 376 2 6292
    cell cycle process 6.0534E-3 2 490 2 6292
    cell cycle 6.95E-3 2 525 2 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    protein binding 9.4468E-3 2 612 2 6292
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle