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View Protein Complex Details

Complex Overview

From Publication: Ho Y. et al. (2002) Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry. Nature. 2002 Jan 10;415(6868):180-3.
Notes: This molecular complex record represents a population of complexes co-purified by immunoprecipitation of FLAG-tagged Arp2. The topolgies of protein complexes in this experiment are unknown.
Complex Size: 5 proteins

Complex Member Proteins

Cellular Component Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

Arp2/3 protein complex 2.5595E-16 5 7 5 6292
actin cytoskeleton 3.9978E-10 5 85 5 6292
cytoskeletal part 3.1693E-8 5 201 5 6292
cytoskeleton 4.5579E-8 5 216 5 6292
non-membrane-bounded organelle 8.1528E-5 5 959 5 6292
intracellular non-membrane-bounded organelle 8.1528E-5 5 959 5 6292
protein complex 1.913E-4 5 1137 5 6292
macromolecular complex 1.1794E-3 5 1635 5 6292
organelle part 6.2578E-3 5 2282 5 6292
intracellular organelle part 6.2578E-3 5 2282 5 6292

Biological Process Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

mitochondrion inheritance 1.4474E-12 5 29 5 6292
mitochondrion distribution 1.4474E-12 5 29 5 6292
mitochondrion localization 1.7368E-12 5 30 5 6292
organelle inheritance 1.3236E-11 5 44 5 6292
organelle localization 3.9978E-10 5 85 5 6292
actin cytoskeleton organization 1.7107E-9 5 113 5 6292
actin filament-based process 2.0421E-9 5 117 5 6292
mitochondrion organization 8.7955E-9 5 156 5 6292
cytoskeleton organization 6.3956E-8 5 231 5 6292
cellular localization 1.0991E-5 5 643 5 6292
actin filament organization 1.1891E-5 5 68 3 6292
actin cortical patch assembly 4.5804E-5 5 14 2 6292
cortical actin cytoskeleton organization 5.2834E-5 5 15 2 6292
cortical cytoskeleton organization 5.2834E-5 5 15 2 6292
localization 1.3464E-4 5 1060 5 6292
organelle organization 1.8302E-4 5 1127 5 6292
cellular component organization 1.0001E-3 5 1582 5 6292
actin nucleation 2.3825E-3 5 3 1 6292

Molecular Function Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

actin binding 3.1914E-7 5 21 3 6292
structural molecule activity 4.4145E-7 5 339 5 6292
structural constituent of cytoskeleton 5.5782E-6 5 53 3 6292
cytoskeletal protein binding 7.7299E-6 5 59 3 6292
ATP binding 1.3848E-4 5 24 2 6292
adenyl ribonucleotide binding 1.5047E-4 5 25 2 6292
adenyl nucleotide binding 2.1784E-4 5 30 2 6292
purine nucleoside binding 2.3279E-4 5 31 2 6292
nucleoside binding 2.4823E-4 5 32 2 6292
ribonucleotide binding 4.092E-4 5 41 2 6292
purine ribonucleotide binding 4.092E-4 5 41 2 6292
purine nucleotide binding 6.594E-4 5 52 2 6292
nucleotide binding 8.4895E-4 5 59 2 6292
protein binding 7.8822E-3 5 612 3 6292

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