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View Protein Complex Details

Complex Overview

From Publication: Riffle <i>et al</i>. (2010) (Unpublished Data)
Notes: Complex predicted from the combined set of Gavin (2002), Gavin (2006), Ho (2002) and Krogan (2006); at p-value cutoff of 1E-7
Complex Size: 8 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
RPL15A
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • translation
  • RNA binding
  • structural constituent of ribosome
  • RPL1A, RPL1B
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • regulation of translation
  • RNA processing
  • translation
  • RNA binding
  • structural constituent of ribosome
  • RPL2A, RPL2B
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • regulation of translation
  • response to drug
  • translation
  • RNA binding
  • structural constituent of ribosome
  • rRNA binding
  • RPL6A
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • ribosomal large subunit assembly
  • translation
  • RNA binding
  • structural constituent of ribosome
  • RPL8A
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • translation
  • structural constituent of ribosome
  • RPS1B
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic small ribosomal subunit
  • ribosome
  • 90S preribosome
  • intracellular
  • translation
  • structural constituent of ribosome
  • RPS6A, RPS6B
  • small-subunit processome
  • nucleus
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic small ribosomal subunit
  • ribosome
  • nucleolus
  • 90S preribosome
  • intracellular
  • maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • ribosome biogenesis
  • rRNA processing
  • translation
  • structural constituent of ribosome
  • RPS7A
  • small nucleolar ribonucleoprotein complex
  • translation
  • structural constituent of ribosome
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    cytosolic ribosome 1.7589E-12 8 101 7 6292
    cytosolic part 6.8298E-12 8 122 7 6292
    ribosomal subunit 1.2273E-10 8 183 7 6292
    ribonucleoprotein complex 1.8861E-9 8 514 8 6292
    cytosol 2.7341E-9 8 284 7 6292
    ribosome 3.1671E-9 8 290 7 6292
    cytosolic large ribosomal subunit 3.6467E-9 8 60 5 6292
    large ribosomal subunit 8.0096E-8 8 110 5 6292
    non-membrane-bounded organelle 1.3016E-5 8 959 7 6292
    intracellular non-membrane-bounded organelle 1.3016E-5 8 959 7 6292
    macromolecular complex 2.0527E-5 8 1635 8 6292
    90S preribosome 1.9058E-4 8 17 2 6292
    preribosome 7.7767E-4 8 34 2 6292
    cytosolic small ribosomal subunit 9.7204E-4 8 38 2 6292
    small ribosomal subunit 3.5536E-3 8 73 2 6292
    organelle part 4.4856E-3 8 2282 7 6292
    intracellular organelle part 4.4856E-3 8 2282 7 6292
    small-subunit processome 7.6075E-3 8 6 1 6292
    cytoplasmic part 7.7532E-3 8 2482 7 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    translation 1.5155E-10 8 376 8 6292
    cellular protein metabolic process 7.0519E-7 8 1074 8 6292
    protein metabolic process 1.1064E-6 8 1136 8 6292
    cellular macromolecule biosynthetic process 1.5738E-6 8 1187 8 6292
    macromolecule biosynthetic process 1.5953E-6 8 1189 8 6292
    gene expression 2.9372E-6 8 1283 8 6292
    cellular biosynthetic process 1.4602E-5 8 1567 8 6292
    biosynthetic process 1.7431E-5 8 1602 8 6292
    cellular macromolecule metabolic process 3.0018E-4 8 2285 8 6292
    macromolecule metabolic process 3.7455E-4 8 2349 8 6292
    primary metabolic process 2.0036E-3 8 2896 8 6292
    regulation of translation 2.1802E-3 8 57 2 6292
    posttranscriptional regulation of gene expression 2.4935E-3 8 61 2 6292
    cellular metabolic process 2.9013E-3 8 3033 8 6292
    regulation of cellular protein metabolic process 3.0901E-3 8 68 2 6292
    regulation of protein metabolic process 3.6499E-3 8 74 2 6292
    metabolic process 3.9991E-3 8 3157 8 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    structural constituent of ribosome 1.4597E-12 8 212 8 6292
    structural molecule activity 6.5627E-11 8 339 8 6292
    RNA binding 6.6069E-4 8 367 4 6292
    nucleic acid binding 6.1432E-3 8 666 4 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle