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View Protein Complex Details

Complex Overview

From Publication: Riffle <i>et al</i>. (2010) (Unpublished Data)
Notes: Complex predicted from the combined set of Gavin (2002), Gavin (2006), Ho (2002) and Krogan (2006); at p-value cutoff of 1E-7
Complex Size: 8 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
ABP1
  • cytoskeleton
  • cytoplasm
  • cell cortex
  • actin cortical patch assembly
  • protein binding
  • CMD1
  • incipient cellular bud site
  • cellular bud tip
  • central plaque of spindle pole body
  • cytoplasm
  • cellular bud neck
  • mating projection tip
  • cytoskeleton organization
  • cell budding
  • vacuole fusion, non-autophagic
  • mitosis
  • endocytosis
  • protein binding
  • calcium ion binding
  • calcium-dependent protein binding
  • CRN1
  • actin cortical patch
  • actin filament organization
  • microtubule-based process
  • actin filament binding
  • protein binding, bridging
  • microtubule binding
  • INP52
  • membrane fraction
  • actin cortical patch
  • cellular cell wall organization
  • inositol lipid-mediated signaling
  • endocytosis
  • phosphoinositide dephosphorylation
  • phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity
  • inositol-polyphosphate 5-phosphatase activity
  • LSP1
  • cytoplasm
  • mitochondrion
  • mitochondrial outer membrane
  • eisosome
  • response to heat
  • endocytosis
  • protein kinase inhibitor activity
  • MLC1
  • cellular bud tip
  • cellular bud neck
  • vesicle
  • cytokinesis, actomyosin contractile ring assembly
  • vesicle targeting
  • protein localization
  • cytokinesis
  • myosin II heavy chain binding
  • myosin V binding
  • PIL1
  • cytoplasm
  • mitochondrion
  • mitochondrial outer membrane
  • eisosome
  • response to heat
  • protein localization
  • endocytosis
  • protein kinase inhibitor activity
  • RVS161
  • mating projection
  • membrane raft
  • actin cortical patch
  • bipolar cellular bud site selection
  • response to osmotic stress
  • endocytosis
  • cytoskeletal protein binding
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    cell cortex 6.4112E-10 8 109 6 6292
    cell cortex part 4.0227E-8 8 96 5 6292
    eisosome 1.4147E-6 8 2 2 6292
    cytoskeleton 2.3444E-6 8 216 5 6292
    actin cortical patch 1.4063E-5 8 41 3 6292
    cortical actin cytoskeleton 2.8964E-5 8 52 3 6292
    cortical cytoskeleton 2.8964E-5 8 52 3 6292
    cytoskeletal part 6.3984E-5 8 201 4 6292
    actin cytoskeleton 1.2691E-4 8 85 3 6292
    cell projection 1.6147E-3 8 49 2 6292
    mating projection 1.6147E-3 8 49 2 6292
    cellular bud tip 2.1802E-3 8 57 2 6292
    non-membrane-bounded organelle 3.0487E-3 8 959 5 6292
    intracellular non-membrane-bounded organelle 3.0487E-3 8 959 5 6292
    mitochondrial outer membrane 5.5921E-3 8 92 2 6292
    central plaque of spindle pole body 6.3431E-3 8 5 1 6292
    cytoplasmic part 7.7532E-3 8 2482 7 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    endocytosis 2.5866E-8 8 88 5 6292
    membrane invagination 3.6154E-8 8 94 5 6292
    vesicle-mediated transport 6.0898E-7 8 340 6 6292
    cellular membrane organization 1.522E-6 8 198 5 6292
    membrane organization 1.522E-6 8 198 5 6292
    cellular component organization 1.5761E-5 8 1582 8 6292
    cytoskeleton organization 1.1032E-4 8 231 4 6292
    actin cytoskeleton organization 2.9581E-4 8 113 3 6292
    transport 3.2749E-4 8 997 6 6292
    actin filament-based process 3.2786E-4 8 117 3 6292
    response to abiotic stimulus 3.2786E-4 8 117 3 6292
    establishment of localization 3.4863E-4 8 1008 6 6292
    response to heat 3.8504E-4 8 24 2 6292
    localization 4.641E-4 8 1060 6 6292
    cell division 6.1672E-4 8 145 3 6292
    response to temperature stimulus 6.4583E-4 8 31 2 6292
    establishment of vesicle localization 2.5415E-3 8 2 1 6292
    vesicle targeting 2.5415E-3 8 2 1 6292
    actomyosin structure organization 3.8101E-3 8 3 1 6292
    cytokinesis, actomyosin contractile ring assembly 3.8101E-3 8 3 1 6292
    assembly of actomyosin apparatus involved in cell cycle cytokinesis 3.8101E-3 8 3 1 6292
    cell cycle cytokinesis 4.2539E-3 8 80 2 6292
    vesicle localization 5.0773E-3 8 4 1 6292
    cell budding 5.3571E-3 8 90 2 6292
    asexual reproduction 5.3571E-3 8 90 2 6292
    cytokinetic process 5.5921E-3 8 92 2 6292
    cytokinesis 8.1985E-3 8 112 2 6292
    phosphoinositide dephosphorylation 8.8705E-3 8 7 1 6292
    phospholipid dephosphorylation 8.8705E-3 8 7 1 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    cytoskeletal protein binding 4.2427E-5 8 59 3 6292
    protein kinase inhibitor activity 7.7367E-5 8 11 2 6292
    kinase inhibitor activity 7.7367E-5 8 11 2 6292
    protein binding 3.7374E-4 8 612 5 6292
    enzyme inhibitor activity 4.8874E-4 8 27 2 6292
    calcium-dependent protein binding 1.2715E-3 8 1 1 6292
    myosin heavy chain binding 1.2715E-3 8 1 1 6292
    myosin II heavy chain binding 1.2715E-3 8 1 1 6292
    myosin V binding 1.2715E-3 8 1 1 6292
    protein kinase regulator activity 1.4238E-3 8 46 2 6292
    kinase regulator activity 1.6147E-3 8 49 2 6292
    myosin II binding 2.5415E-3 8 2 1 6292
    inositol-polyphosphate 5-phosphatase activity 3.8101E-3 8 3 1 6292
    inositol trisphosphate phosphatase activity 3.8101E-3 8 3 1 6292
    phosphoinositide 5-phosphatase activity 5.0773E-3 8 4 1 6292
    phosphatidylinositol bisphosphate phosphatase activity 5.0773E-3 8 4 1 6292
    phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity 5.0773E-3 8 4 1 6292
    myosin binding 6.3431E-3 8 5 1 6292
    calcium ion binding 8.8705E-3 8 7 1 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle