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View Protein Complex Details

Complex Overview

From Publication: Riffle <i>et al</i>. (2010) (Unpublished Data)
Notes: Complex predicted from the combined set of Gavin (2002), Gavin (2006), Ho (2002) and Krogan (2006); at p-value cutoff of 1E-7
Complex Size: 6 proteins

Complex Member Proteins

Protein

 GO Cellular Component GO Biological Process GO Molecular Function
RPA135
  • DNA-directed RNA polymerase I complex
    		•
  • transcription from RNA polymerase I promoter
  • ribosome biogenesis
    		•
  • DNA-directed RNA polymerase activity
    		•
    RPB10
  • DNA-directed RNA polymerase I complex
  • DNA-directed RNA polymerase III complex
  • DNA-directed RNA polymerase II, core complex
    		•
  • transcription from RNA polymerase III promoter
  • transcription from RNA polymerase I promoter
  • transcription from RNA polymerase II promoter
    		•
  • DNA-directed RNA polymerase activity
    		•
    RPB2
  • mitochondrion
  • DNA-directed RNA polymerase II, core complex
    		•
  • transcription from RNA polymerase II promoter
    		•
  • DNA-directed RNA polymerase activity
    		•
    RPB5
  • DNA-directed RNA polymerase I complex
  • DNA-directed RNA polymerase III complex
  • DNA-directed RNA polymerase II, core complex
    		•
  • transcription from RNA polymerase III promoter
  • transcription from RNA polymerase I promoter
  • transcription from RNA polymerase II promoter
    		•
  • DNA-directed RNA polymerase activity
    		•
    RPB8
  • DNA-directed RNA polymerase I complex
  • DNA-directed RNA polymerase III complex
  • DNA-directed RNA polymerase II, core complex
    		•
  • transcription from RNA polymerase III promoter
  • transcription from RNA polymerase I promoter
  • transcription from RNA polymerase II promoter
    		•
  • DNA-directed RNA polymerase activity
    		•
    RPO26
  • DNA-directed RNA polymerase I complex
  • DNA-directed RNA polymerase III complex
  • DNA-directed RNA polymerase II, core complex
    		•
  • transcription from RNA polymerase III promoter
  • transcription from RNA polymerase I promoter
  • transcription from RNA polymerase II promoter
    		•
  • DNA-directed RNA polymerase activity
    		•

    Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    RNA polymerase complex 8.5641E-15 6 31 6 6292
    nuclear DNA-directed RNA polymerase complex 8.5641E-15 6 31 6 6292
    DNA-directed RNA polymerase complex 8.5641E-15 6 31 6 6292
    DNA-directed RNA polymerase II, core complex 5.7863E-14 6 12 5 6292
    DNA-directed RNA polymerase I complex 1.4623E-13 6 14 5 6292
    nucleolar part 8.887E-11 6 45 5 6292
    DNA-directed RNA polymerase II, holoenzyme 2.7744E-10 6 56 5 6292
    DNA-directed RNA polymerase III complex 5.4538E-10 6 17 4 6292
    nuclear lumen 1.3504E-7 6 453 6 6292
    nucleolus 2.3635E-7 6 211 5 6292
    nucleoplasm part 4.9986E-7 6 245 5 6292
    nucleoplasm 7.2644E-7 6 264 5 6292
    organelle lumen 1.3052E-6 6 660 6 6292
    intracellular organelle lumen 1.3052E-6 6 660 6 6292
    membrane-enclosed lumen 1.8602E-6 6 700 6 6292
    nuclear part 2.8697E-5 6 1103 6 6292
    protein complex 3.4445E-5 6 1137 6 6292
    macromolecular complex 3.0579E-4 6 1635 6 6292
    non-membrane-bounded organelle 4.2731E-4 6 959 5 6292
    intracellular non-membrane-bounded organelle 4.2731E-4 6 959 5 6292
    nucleus 1.1592E-3 6 2041 6 6292
    organelle part 2.2664E-3 6 2282 6 6292
    intracellular organelle part 2.2664E-3 6 2282 6 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    transcription from RNA polymerase I promoter 1.0387E-11 6 30 5 6292
    transcription from RNA polymerase III promoter 1.6824E-8 6 38 4 6292
    transcription, DNA-dependent 2.5393E-7 6 503 6 6292
    RNA biosynthetic process 2.6954E-7 6 508 6 6292
    transcription 4.4473E-7 6 552 6 6292
    transcription from RNA polymerase II promoter 2.386E-6 6 335 5 6292
    RNA metabolic process 1.1988E-5 6 954 6 6292
    cellular macromolecule biosynthetic process 4.4618E-5 6 1187 6 6292
    macromolecule biosynthetic process 4.5072E-5 6 1189 6 6292
    gene expression 7.1216E-5 6 1283 6 6292
    nucleic acid metabolic process 1.283E-4 6 1415 6 6292
    nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 2.3599E-4 6 1566 6 6292
    cellular biosynthetic process 2.3689E-4 6 1567 6 6292
    biosynthetic process 2.7052E-4 6 1602 6 6292
    cellular nitrogen compound metabolic process 4.9256E-4 6 1770 6 6292
    nitrogen compound metabolic process 5.2873E-4 6 1791 6 6292
    cellular macromolecule metabolic process 2.2844E-3 6 2285 6 6292
    macromolecule metabolic process 2.6967E-3 6 2349 6 6292
    primary metabolic process 9.4808E-3 6 2896 6 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    RNA polymerase activity 1.5643E-14 6 34 6 6292
    DNA-directed RNA polymerase activity 1.5643E-14 6 34 6 6292
    nucleotidyltransferase activity 3.3186E-10 6 168 6 6292
    transferase activity, transferring phosphorus-containing groups 8.555E-8 6 420 6 6292
    transferase activity 4.0631E-6 6 797 6 6292
    catalytic activity 1.5845E-3 6 2150 6 6292
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle