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View Protein Complex Details

Complex Overview

From Publication: Riffle <i>et al</i>. (2010) (Unpublished Data)
Notes: Complex predicted from the combined set of Gavin (2002), Gavin (2006), Ho (2002) and Krogan (2006); at p-value cutoff of 1E-7
Complex Size: 10 proteins

Complex Member Proteins

Protein

 GO Cellular Component GO Biological Process GO Molecular Function
RET1
  • DNA-directed RNA polymerase III complex
    		•
  • transcription from RNA polymerase III promoter
    		•
  • DNA-directed RNA polymerase activity
    		•
    RPA135
  • DNA-directed RNA polymerase I complex
    		•
  • transcription from RNA polymerase I promoter
  • ribosome biogenesis
    		•
  • DNA-directed RNA polymerase activity
    		•
    RPA190
  • DNA-directed RNA polymerase I complex
    		•
  • transcription from RNA polymerase I promoter
    		•
  • DNA-directed RNA polymerase activity
    		•
    RPA49
  • DNA-directed RNA polymerase I complex
    		•
  • transcription from RNA polymerase I promoter
  • regulation of cell size
  • ribosome biogenesis
    		•
  • DNA-directed RNA polymerase activity
    		•
    RPB10
  • DNA-directed RNA polymerase I complex
  • DNA-directed RNA polymerase III complex
  • DNA-directed RNA polymerase II, core complex
    		•
  • transcription from RNA polymerase III promoter
  • transcription from RNA polymerase I promoter
  • transcription from RNA polymerase II promoter
    		•
  • DNA-directed RNA polymerase activity
    		•
    RPB5
  • DNA-directed RNA polymerase I complex
  • DNA-directed RNA polymerase III complex
  • DNA-directed RNA polymerase II, core complex
    		•
  • transcription from RNA polymerase III promoter
  • transcription from RNA polymerase I promoter
  • transcription from RNA polymerase II promoter
    		•
  • DNA-directed RNA polymerase activity
    		•
    RPB8
  • DNA-directed RNA polymerase I complex
  • DNA-directed RNA polymerase III complex
  • DNA-directed RNA polymerase II, core complex
    		•
  • transcription from RNA polymerase III promoter
  • transcription from RNA polymerase I promoter
  • transcription from RNA polymerase II promoter
    		•
  • DNA-directed RNA polymerase activity
    		•
    RPC19
  • DNA-directed RNA polymerase I complex
  • DNA-directed RNA polymerase III complex
    		•
  • transcription from RNA polymerase III promoter
  • transcription from RNA polymerase I promoter
  • ribosome biogenesis
    		•
  • DNA-directed RNA polymerase activity
    		•
    RPC40
  • DNA-directed RNA polymerase I complex
  • DNA-directed RNA polymerase III complex
    		•
  • transcription from RNA polymerase III promoter
  • transcription from RNA polymerase I promoter
  • ribosome biogenesis
    		•
  • DNA-directed RNA polymerase activity
    		•
    RPO26
  • DNA-directed RNA polymerase I complex
  • DNA-directed RNA polymerase III complex
  • DNA-directed RNA polymerase II, core complex
    		•
  • transcription from RNA polymerase III promoter
  • transcription from RNA polymerase I promoter
  • transcription from RNA polymerase II promoter
    		•
  • DNA-directed RNA polymerase activity
    		•

    Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    DNA-directed RNA polymerase I complex 4.7239E-25 10 14 9 6292
    RNA polymerase complex 1.6669E-24 10 31 10 6292
    nuclear DNA-directed RNA polymerase complex 1.6669E-24 10 31 10 6292
    DNA-directed RNA polymerase complex 1.6669E-24 10 31 10 6292
    nucleolar part 2.0817E-19 10 45 9 6292
    DNA-directed RNA polymerase III complex 3.0102E-17 10 17 7 6292
    nucleolus 4.4062E-13 10 211 9 6292
    nuclear lumen 3.41E-12 10 453 10 6292
    organelle lumen 1.5167E-10 10 660 10 6292
    intracellular organelle lumen 1.5167E-10 10 660 10 6292
    membrane-enclosed lumen 2.7426E-10 10 700 10 6292
    DNA-directed RNA polymerase II, core complex 1.5836E-9 10 12 4 6292
    nucleoplasm part 1.3547E-8 10 245 7 6292
    nucleoplasm 2.2806E-8 10 264 7 6292
    nuclear part 2.6498E-8 10 1103 10 6292
    protein complex 3.5941E-8 10 1137 10 6292
    non-membrane-bounded organelle 3.7143E-7 10 959 9 6292
    intracellular non-membrane-bounded organelle 3.7143E-7 10 959 9 6292
    DNA-directed RNA polymerase II, holoenzyme 1.1361E-6 10 56 4 6292
    macromolecular complex 1.3754E-6 10 1635 10 6292
    nucleus 1.2708E-5 10 2041 10 6292
    organelle part 3.8887E-5 10 2282 10 6292
    intracellular organelle part 3.8887E-5 10 2282 10 6292
    membrane-bounded organelle 5.9511E-3 10 3771 10 6292
    intracellular membrane-bounded organelle 5.9511E-3 10 3771 10 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    transcription from RNA polymerase I promoter 3.3682E-21 10 30 9 6292
    transcription from RNA polymerase III promoter 1.9363E-14 10 38 7 6292
    transcription, DNA-dependent 9.813E-12 10 503 10 6292
    RNA biosynthetic process 1.0843E-11 10 508 10 6292
    transcription 2.5061E-11 10 552 10 6292
    RNA metabolic process 6.1681E-9 10 954 10 6292
    cellular macromolecule biosynthetic process 5.5363E-8 10 1187 10 6292
    macromolecule biosynthetic process 5.6306E-8 10 1189 10 6292
    gene expression 1.2084E-7 10 1283 10 6292
    nucleic acid metabolic process 3.2281E-7 10 1415 10 6292
    nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 8.9255E-7 10 1566 10 6292
    cellular biosynthetic process 8.9828E-7 10 1567 10 6292
    biosynthetic process 1.121E-6 10 1602 10 6292
    cellular nitrogen compound metabolic process 3.0471E-6 10 1770 10 6292
    nitrogen compound metabolic process 3.4296E-6 10 1791 10 6292
    cellular macromolecule metabolic process 3.9402E-5 10 2285 10 6292
    macromolecule metabolic process 5.1966E-5 10 2349 10 6292
    primary metabolic process 4.2311E-4 10 2896 10 6292
    cellular metabolic process 6.7219E-4 10 3033 10 6292
    metabolic process 1.0041E-3 10 3157 10 6292
    transcription from RNA polymerase II promoter 1.283E-3 10 335 4 6292
    ribosome biogenesis 1.4482E-3 10 346 4 6292
    ribonucleoprotein complex biogenesis 1.9363E-3 10 374 4 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    RNA polymerase activity 4.9281E-24 10 34 10 6292
    DNA-directed RNA polymerase activity 4.9281E-24 10 34 10 6292
    nucleotidyltransferase activity 1.4117E-16 10 168 10 6292
    transferase activity, transferring phosphorus-containing groups 1.5879E-12 10 420 10 6292
    transferase activity 1.012E-9 10 797 10 6292
    catalytic activity 2.1404E-5 10 2150 10 6292
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle