






| From Publication: | Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054 | 
| Notes: | Classifier used Gene Ontology annotations. [FDR: 0.084] [SVM Score: 0.445882151953] | 
| Complex Size: | 2 proteins | 
| Protein | GO Cellular Component | GO Biological Process | GO Molecular Function | 
| CDC13 |  |  |  | 
| TBF1 |  |  |  | 
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
| GO Term | P-value | A | B | I | T | 
| nuclear chromosome, telomeric region | 1.2783E-5 | 2 | 23 | 2 | 6292 | 
| chromosome, telomeric region | 1.7735E-5 | 2 | 27 | 2 | 6292 | 
| nuclear chromosome part | 9.0721E-4 | 2 | 190 | 2 | 6292 | 
| nuclear chromosome | 1.3075E-3 | 2 | 228 | 2 | 6292 | 
| chromosomal part | 1.413E-3 | 2 | 237 | 2 | 6292 | 
| chromosome | 1.8898E-3 | 2 | 274 | 2 | 6292 | 
| telomere cap complex | 3.4937E-3 | 2 | 11 | 1 | 6292 | 
| nuclear telomere cap complex | 3.4937E-3 | 2 | 11 | 1 | 6292 | 
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
| GO Term | P-value | A | B | I | T | 
| telomere capping | 1.5888E-3 | 2 | 5 | 1 | 6292 | 
| loss of chromatin silencing | 3.1764E-3 | 2 | 10 | 1 | 6292 | 
| regulation of gene silencing | 3.4937E-3 | 2 | 11 | 1 | 6292 | 
| negative regulation of gene silencing | 3.4937E-3 | 2 | 11 | 1 | 6292 | 
| positive regulation of gene expression, epigenetic | 3.4937E-3 | 2 | 11 | 1 | 6292 | 
| regulation of chromatin silencing | 3.4937E-3 | 2 | 11 | 1 | 6292 | 
| negative regulation of chromatin silencing | 3.4937E-3 | 2 | 11 | 1 | 6292 | 
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
| GO Term | P-value | A | B | I | T | 
| chromatin insulator sequence binding | 3.1786E-4 | 2 | 1 | 1 | 6292 | 
| DNA binding | 1.6492E-3 | 2 | 256 | 2 | 6292 | 
| chromatin DNA binding | 2.5415E-3 | 2 | 8 | 1 | 6292 | 
| telomeric DNA binding | 3.811E-3 | 2 | 12 | 1 | 6292 |