From Publication: | Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054 |
Notes: | Classifier used Gene Ontology annotations. [FDR: 0.099] [SVM Score: 0.546456384276] |
Complex Size: | 2 proteins |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
endoplasmic reticulum membrane | 4.4352E-4 | 2 | 133 | 2 | 6292 |
endoplasmic reticulum part | 5.6464E-4 | 2 | 150 | 2 | 6292 |
subsynaptic reticulum | 5.6464E-4 | 2 | 150 | 2 | 6292 |
nuclear membrane-endoplasmic reticulum network | 1.3539E-3 | 2 | 232 | 2 | 6292 |
translocon complex | 1.5888E-3 | 2 | 5 | 1 | 6292 |
Sec61 translocon complex | 1.5888E-3 | 2 | 5 | 1 | 6292 |
endoplasmic reticulum | 3.3381E-3 | 2 | 364 | 2 | 6292 |
rough endoplasmic reticulum | 3.811E-3 | 2 | 12 | 1 | 6292 |
rough endoplasmic reticulum membrane | 3.811E-3 | 2 | 12 | 1 | 6292 |
endomembrane system | 3.9918E-3 | 2 | 398 | 2 | 6292 |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
posttranslational protein targeting to membrane, translocation | 1.2712E-3 | 2 | 4 | 1 | 6292 |
posttranslational protein targeting to membrane | 2.859E-3 | 2 | 9 | 1 | 6292 |
SRP-dependent cotranslational protein targeting to membrane, translocation | 3.4937E-3 | 2 | 11 | 1 | 6292 |
SRP-dependent cotranslational protein targeting to membrane | 6.6645E-3 | 2 | 21 | 1 | 6292 |
cotranslational protein targeting to membrane | 7.6148E-3 | 2 | 24 | 1 | 6292 |
intracellular transport | 7.7118E-3 | 2 | 553 | 2 | 6292 |
retrograde vesicle-mediated transport, Golgi to ER | 8.248E-3 | 2 | 26 | 1 | 6292 |
establishment of localization in cell | 9.0494E-3 | 2 | 599 | 2 | 6292 |
vesicle fusion | 9.1975E-3 | 2 | 29 | 1 | 6292 |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
ARF guanyl-nucleotide exchange factor activity | 1.9064E-3 | 2 | 6 | 1 | 6292 |