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View Protein Complex Details

Complex Overview

From Publication: Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054
Notes: Classifier used Gene Ontology annotations. [FDR: 0.069] [SVM Score: 0.54660294608]
Complex Size: 2 proteins

Complex Member Proteins

Protein

 GO Cellular Component GO Biological Process GO Molecular Function
SEC12
  • integral to endoplasmic reticulum membrane
  • integral to membrane of membrane fraction
    		•
  • ER to Golgi vesicle-mediated transport
  • ER-associated protein catabolic process
    		•
  • guanyl-nucleotide exchange factor activity
    		•
    YOS1
  • endoplasmic reticulum membrane
  • integral to Golgi membrane
  • ER to Golgi transport vesicle
    		•
  • ER to Golgi vesicle-mediated transport
    		•
  • molecular_function
    		•

    Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    integral to organelle membrane 1.051E-4 2 65 2 6292
    intrinsic to organelle membrane 1.151E-4 2 68 2 6292
    endoplasmic reticulum membrane 4.4352E-4 2 133 2 6292
    endoplasmic reticulum part 5.6464E-4 2 150 2 6292
    subsynaptic reticulum 5.6464E-4 2 150 2 6292
    integral to membrane of membrane fraction 9.5344E-4 2 3 1 6292
    nuclear membrane-endoplasmic reticulum network 1.3539E-3 2 232 2 6292
    integral to membrane 1.6363E-3 2 255 2 6292
    intrinsic to membrane 1.7276E-3 2 262 2 6292
    endoplasmic reticulum 3.3381E-3 2 364 2 6292
    endomembrane system 3.9918E-3 2 398 2 6292
    integral to Golgi membrane 5.0798E-3 2 16 1 6292
    intrinsic to Golgi membrane 5.0798E-3 2 16 1 6292
    integral to endoplasmic reticulum membrane 9.8303E-3 2 31 1 6292
    ER to Golgi transport vesicle 9.8303E-3 2 31 1 6292
    intrinsic to endoplasmic reticulum membrane 9.8303E-3 2 31 1 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    ER to Golgi vesicle-mediated transport 1.7194E-4 2 83 2 6292
    Golgi vesicle transport 7.0879E-4 2 168 2 6292
    vesicle-mediated transport 2.9119E-3 2 340 2 6292
    intracellular transport 7.7118E-3 2 553 2 6292
    establishment of localization in cell 9.0494E-3 2 599 2 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle