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View Protein Complex Details

Complex Overview

From Publication: Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054
Notes: Classifier used Gene Ontology annotations. [FDR: 0.054] [SVM Score: 0.596919178183]
Complex Size: 2 proteins

Complex Member Proteins

Protein

 GO Cellular Component GO Biological Process GO Molecular Function
COX17
  • mitochondrial intermembrane space
  • mitochondrion
  • cytosol
    		•
  • intracellular copper ion transport
  • respiratory chain complex IV assembly
    		•
  • thioredoxin peroxidase activity
  • copper chaperone activity
    		•
    SCO1
  • mitochondrion
  • mitochondrial inner membrane
    		•
  • copper ion transport
  • protein complex assembly
    		•
  • copper ion binding
  • thioredoxin peroxidase activity
    		•

    Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    mitochondrial envelope 2.4514E-3 2 312 2 6292
    mitochondrial part 5.6881E-3 2 475 2 6292
    envelope 6.43E-3 2 505 2 6292
    organelle envelope 6.43E-3 2 505 2 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    copper ion transport 3.3348E-6 2 12 2 6292
    transition metal ion transport 4.5626E-5 2 43 2 6292
    metal ion transport 8.3521E-5 2 58 2 6292
    cation transport 2.256E-4 2 95 2 6292
    ion transport 3.6076E-4 2 120 2 6292
    protein complex assembly 6.0304E-4 2 155 2 6292
    protein complex biogenesis 6.0304E-4 2 155 2 6292
    intracellular copper ion transport 1.5888E-3 2 5 1 6292
    macromolecular complex assembly 1.9877E-3 2 281 2 6292
    respiratory chain complex IV assembly 2.5415E-3 2 8 1 6292
    macromolecular complex subunit organization 3.2108E-3 2 357 2 6292
    cellular component assembly 3.7349E-3 2 385 2 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    thioredoxin peroxidase activity 1.819E-6 2 9 2 6292
    copper ion binding 1.819E-6 2 9 2 6292
    peroxiredoxin activity 1.819E-6 2 9 2 6292
    peroxidase activity 9.6001E-6 2 20 2 6292
    oxidoreductase activity, acting on peroxide as acceptor 9.6001E-6 2 20 2 6292
    oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 1.2783E-5 2 23 2 6292
    transition metal ion binding 1.3945E-5 2 24 2 6292
    antioxidant activity 1.5158E-5 2 25 2 6292
    metal ion binding 7.5032E-5 2 55 2 6292
    ion binding 7.7811E-5 2 56 2 6292
    cation binding 7.7811E-5 2 56 2 6292
    copper chaperone activity 9.5344E-4 2 3 1 6292
    metallochaperone activity 1.2712E-3 2 4 1 6292
    oxidoreductase activity 1.9877E-3 2 281 2 6292
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle