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Protein Overview: ERG11

Protein Complex Data

Mass Spectrometry Data

The following runs contain data for this protein:

  BAIT COMMENTS PUBLICATION
View Run DAD1 Dam1-765 complex purified from yeast with Dad1-TAP Shimogawa MM, et al. (2006)
View Run VAM3 Sample: HX12 - trans-SNARE complex formation and fusion are inhibited (control). Hao Xu, et al. (2010)
View Run MLP2 #25 Asynchronous Prep3-TiO2 Flowthrough Keck JM, et al. (2011)
View Run MLP2 #24 Asynchronous Prep3-TiO2 Phosphopeptide enrichment Keck JM, et al. (2011)
View Run MLP2 #32 Asynchronous Prep-No Phosphopeptide enrichment Keck JM, et al. (2011)

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Microscopy / Localization Data

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  PROTEIN(S) PUBLICATION
View Data ERG11 Huh WK, et al. (2003)

Protein Structure Data


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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#   Region(s) Method Confidence Match Description
1 View Details [1..157]
[208..315]
[381..410]
PSI-BLAST 555.9794 Cytochrome p450 14 alpha-sterol demethylase (cyp51)
2 View Details [158..207]
[316..380]
[411..530]
PSI-BLAST 555.9794 Cytochrome p450 14 alpha-sterol demethylase (cyp51)

Functions predicted (by domain):

# Gene Ontology predictions
1
Term Confidence Notes
  • monooxygenase activity
  • 5.57229509004705 bayes_pls_golite062009
  • steroid hydroxylase activity
  • 5.04794778387361 bayes_pls_golite062009
  • oxysterol 7-alpha-hydroxylase activity
  • 5.03099580095037 bayes_pls_golite062009
  • retinoic acid 4-hydroxylase activity
  • 3.76307535769621 bayes_pls_golite062009
  • demethylase activity
  • 3.40807632433846 bayes_pls_golite062009
  • oxygen binding
  • 3.29945075872446 bayes_pls_golite062009
  • oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
  • 3.24344797738248 bayes_pls_golite062009
  • retinoic acid binding
  • 3.04897926497756 bayes_pls_golite062009
  • arachidonic acid monooxygenase activity
  • 3.03830845324387 bayes_pls_golite062009
  • sterol 14-demethylase activity
  • 2.94610675710811 bayes_pls_golite062009
  • retinoid binding
  • 2.60220937953757 bayes_pls_golite062009
  • isoprenoid binding
  • 2.47826119804163 bayes_pls_golite062009
  • oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
  • 2.41884363121524 bayes_pls_golite062009
  • steroid 7-alpha-hydroxylase activity
  • 2.29989218606587 bayes_pls_golite062009
  • oxidoreductase activity
  • 2.09151585300316 bayes_pls_golite062009
  • vitamin D3 25-hydroxylase activity
  • 1.65825585934141 bayes_pls_golite062009
  • vitamin D 25-hydroxylase activity
  • 1.65825585934141 bayes_pls_golite062009
  • fatty acid (omega-1)-hydroxylase activity
  • 1.65569090470706 bayes_pls_golite062009
  • electron carrier activity
  • 1.48516712188486 bayes_pls_golite062009
  • testosterone 6-beta-hydroxylase activity
  • 1.4661447981611 bayes_pls_golite062009
  • arachidonic acid epoxygenase activity
  • 1.4220050618113 bayes_pls_golite062009
  • binding
  • 1.2866152532988 bayes_pls_golite062009
  • oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen
  • 1.04852693766796 bayes_pls_golite062009
  • vitamin D 24-hydroxylase activity
  • 1.03699542179837 bayes_pls_golite062009
  • steroid 17-alpha-monooxygenase activity
  • 0.918503562996019 bayes_pls_golite062009
  • catalytic activity
  • 0.608111453189583 bayes_pls_golite062009
  • oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen
  • 0.33710488712754 bayes_pls_golite062009
  • transition metal ion binding
  • 0.22562022703652 bayes_pls_golite062009
  • 1-alpha,25-dihydroxyvitamin D3 24-hydroxylase activity
  • 0.169431271735966 bayes_pls_golite062009
  • 25-hydroxycholecalciferol-24-hydroxylase activity
  • 0.167565425989292 bayes_pls_golite062009
    2 No functions predicted.




    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle