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Protein Overview: PURK_ECOLI

General Information:
Name(s) found: PURK_ECOLI [Swiss-Prot]
Description(s) found:
Found 10 descriptions.
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  • Phosphoribosylaminoimidazole carboxylase ATPase subunit (EC 4.1.1.21) (AIR carboxylase) (AIRC) - Escherichia coli [Swiss-Prot]
    • Organism: Escherichia coli
    Length: 355 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKQVCVLGNG QLGRMLRQAG EPLGIAVWPV GLDAEPAAVP FQQSVITAEI ERWPETALTR  60
   61 ELARHPAFVN RDVFPIIADR LTQKQLFDKL HLPTAPWQLL AERSEWPAVF DRLGELAIVK 120
  121 RRTGGYDGRG QWRLRANETE QLPAECYGEC IVEQGINFSG EVSLVGARGF DGSTVFYPLT 180
  181 HNLHQDGILR TSVAFPQANA QQQAQAEEML SAIMQELGYV GVMAMECFVT PQGLLINELA 240
  241 PRVHNSGHWT QNGASISQFE LHLRAITDLP LPQPVVNNPS VMINLIGSDV NYDWLKLPLV 300
  301 HLHWYDKEVR PGRKVGHLNL TDSDTSRLTA TLEALIPLLP PEYASGVIWA QSKFG

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..355] PSI-BLAST 66.69897 N5-carboxyaminoimidazole ribonucleotide synthetase PurK (AIRC), C-domain; N5-carboxyaminoimidazole ribonucleotide synthetase PurK (AIRC), N-domain; N5-carboxyaminoimidazole ribonucleotide synthetase PurK (AIRC), domain 2

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • phosphoribosylaminoimidazole carboxylase activity
    		•  8.30252180826751 bayes_pls_golite062009
  • carboxy-lyase activity
    		•  4.46679646341684 bayes_pls_golite062009
  • ligase activity, forming carbon-nitrogen bonds
    		•  2.99262646198755 bayes_pls_golite062009
  • carbamoyl-phosphate synthase activity
    		•  2.80055235272563 bayes_pls_golite062009
  • carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
    		•  2.72231827182887 bayes_pls_golite062009
  • phosphoribosylamine-glycine ligase activity
    		•  1.37477732460326 bayes_pls_golite062009
  • ligase activity
    		•  1.13657217096051 bayes_pls_golite062009
  • carbon-nitrogen ligase activity, with glutamine as amido-N-donor
    		•  1.11645327303429 bayes_pls_golite062009
  • catalytic activity
    		•  1.08688404807699 bayes_pls_golite062009
  • acid-amino acid ligase activity
    		•  0.730894973410499 bayes_pls_golite062009
  • binding
    		•  0.552939485505354 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.95

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle