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Protein Overview: FMT1

General Information:
Name(s) found: FMT1 / YBL013W [SGD]
Description(s) found:
Found 20 descriptions.
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  • Methionyl-tRNA formyltransferase, catalyzes the formylation of initiator Met-tRNA in mitochondria; potential Cdc28p substrate [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 401 amino acids

    Gene Ontology:
    Cellular Component: mitochondrion [IDALink to PubMed articleLink to PubMed article][TASLink to PubMed article]
    Biological Process: methionyl-tRNA aminoacylation [IDALink to PubMed article]
    translational initiation [IDALink to PubMed article]
    Molecular Function: methionyl-tRNA formyltransferase activity [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVKMRRITPT RLLFTCRYIS NNASPPVQPL NVLFFGSDTF SNFSLQALNE LRQNNGSCGI  60
   61 VDNIQVVTRS PKWCGRQKSI LKYPPIFDMA EKLQLPRPIT CDTKQEMLAL SKLTPSRQGN 120
  121 PENDGSGAPF NAIIAVSFGK LIPGDLIRAV PLALNVHPSL LPRHKGSAPI QRALLEGDTY 180
  181 TGVTIQTLHP DRFDHGAIVA QTEPLAIATM LSKGRVNDST ADFNSEGLPR RTAILMDQLG 240
  241 ALGAQLLGQT LRERLYLPQN RVQAPTAYKP SYAHRITTED KRIHWARDSA AELLNKLETL 300
  301 GPLHAFKEAT AARKDAQNSV LKRILFHECK VMRDARLDNG SKPGMFKYDD IKDCILVTCR 360
  361 GNLLLCVSRL QFEGFAVERA GQFMARLRKR CGALSEKLVF L

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data FMT1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..401] PSI-BLAST 75.0 Methionyl-tRNAfmet formyltransferase, C-terminal domain; Methionyl-tRNAfmet formyltransferase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • methionyl-tRNA formyltransferase activity
    		•  5.51013755462273 bayes_pls_golite062009
  • hydroxymethyl-, formyl- and related transferase activity
    		•  5.19882604023997 bayes_pls_golite062009
  • ligase activity
    		•  2.41579019065074 bayes_pls_golite062009
  • methyltransferase activity
    		•  2.27572765999587 bayes_pls_golite062009
  • transferase activity, transferring one-carbon groups
    		•  2.20102068445328 bayes_pls_golite062009
  • catalytic activity
    		•  2.16003793103722 bayes_pls_golite062009
  • glycine hydroxymethyltransferase activity
    		•  1.99841214906509 bayes_pls_golite062009
  • transferase activity
    		•  1.01502594768782 bayes_pls_golite062009
  • DNA N-glycosylase activity
    		•  0.809924940479886 bayes_pls_golite062009
  • binding
    		•  0.752059276178195 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.698214709916015 bayes_pls_golite062009
  • DNA binding
    		•  0.421388681127685 bayes_pls_golite062009
  • phosphoribosylglycinamide formyltransferase activity
    		•  0.0567687847434473 bayes_pls_golite062009
  • hydrolase activity, hydrolyzing N-glycosyl compounds
    		•  0.0124799003650303 bayes_pls_golite062009


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.83

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle