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Protein Overview: SPAC16E8.17c

General Information:
Name(s) found: SPAC16E8.17c [Sanger Pombe]
Description(s) found:
Found 20 descriptions.
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  • succinate-CoA ligase alpha subunit [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 331 amino acids

    Gene Ontology:
    Cellular Component: mitochondrion [IDALink to PubMed article][ISSLink to PubMed article]
    succinate-CoA ligase complex [ICLink to PubMed article]
    Biological Process: tricarboxylic acid cycle [ISSLink to PubMed article]
    succinyl-CoA metabolic process [ISSLink to PubMed article]
    Molecular Function: GTP binding [IEA]
    succinate-CoA ligase (GDP-forming) activity [IEA]
    ATP citrate synthase activity [IEA]
    succinate-CoA ligase (ADP-forming) activity [IEA]
    succinate-CoA ligase activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFKTQTTLLT SLRRFSSSSQ LKNSKSLYEQ TIPNLMINSD TKVIFQGFTG KQGTFHAQHA  60
   61 MDYGTKVVGG TNPKKAGTTH LGKPVFGTIE EAMKETKADA SAVFVPPPLA AGAIEEAIAA 120
  121 EVPLIVAITE GIPQHDMLRV SDILKTQSKS RLVGPNCPGI IRPGQCKIGI MPSHIHKPGC 180
  181 IGIVSRSGTL TYEAVNQTTQ TDLGQSLVIG IGGDPFPGTN FIDALKLFLD DPNTQGIILI 240
  241 GEIGGSAEED AAEFIRAANA SRSTPKPVVS FIAGATAPKG RRMGHAGAIV AGGKGTAAAK 300
  301 FEALEAAGVR ISRSPATLGS LIVEELNKLK H

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..331] PSI-BLAST 82.0 Succinyl-CoA synthetase, alpha-chain, N-terminal (CoA-binding) domain; Succinyl-CoA synthetase, alpha-chain, C-terminal domain

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • succinate-CoA ligase activity
    		•  11.5979130191209 bayes_pls_golite062009
  • succinate-CoA ligase (GDP-forming) activity
    		•  10.9659410855563 bayes_pls_golite062009
  • CoA-ligase activity
    		•  10.4192804448897 bayes_pls_golite062009
  • acid-thiol ligase activity
    		•  10.243481928473 bayes_pls_golite062009
  • ligase activity, forming carbon-sulfur bonds
    		•  9.48706872092269 bayes_pls_golite062009
  • succinate-CoA ligase (ADP-forming) activity
    		•  9.35325976720833 bayes_pls_golite062009
  • malate dehydrogenase activity
    		•  4.38786524125089 bayes_pls_golite062009
  • oxidoreductase activity
    		•  3.09625241707629 bayes_pls_golite062009
  • transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer
    		•  3.07329302783164 bayes_pls_golite062009
  • ligase activity
    		•  2.30626698552338 bayes_pls_golite062009
  • catalytic activity
    		•  1.90735517755117 bayes_pls_golite062009
  • oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor
    		•  1.70038641098437 bayes_pls_golite062009
  • oxidoreductase activity, acting on CH-OH group of donors
    		•  1.65338499044318 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
    		•  1.47309297191111 bayes_pls_golite062009
  • malic enzyme activity
    		•  1.2147813077436 bayes_pls_golite062009
  • transferase activity, transferring acyl groups
    		•  1.15639517822408 bayes_pls_golite062009
  • L-malate dehydrogenase activity
    		•  1.02646414923682 bayes_pls_golite062009
  • oxidoreductase activity, acting on NADH or NADPH
    		•  0.99118526697655 bayes_pls_golite062009
  • ATP citrate synthase activity
    		•  0.917482134347073 bayes_pls_golite062009
  • monovalent inorganic cation transmembrane transporter activity
    		•  0.576163737662951 bayes_pls_golite062009
  • malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+) activity
    		•  0.120195861875768 bayes_pls_golite062009
  • inorganic cation transmembrane transporter activity
    		•  0.0913823272876781 bayes_pls_golite062009
  • alcohol dehydrogenase (NAD) activity
    		•  0.00644214957417527 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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