YRC Public Data Repository - Protein Structure Prediction

Protein:	SPAC16E8.17c
Organism:	Schizosaccharomyces pombe
Length:	331 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPAC16E8.17c.

Description	E-value	Query Range	Subject Range
SUCA1_SOLLC - Succinyl-CoA ligase [ADP-forming] subunit alpha-1, mitochondrial OS=Solanum lycopersicum GN=SCOA PE=...	322.0	[0..1]	[329..1]
SUCA2_ARATH - Succinyl-CoA ligase [ADP-forming] subunit alpha-2, mitochondrial OS=Arabidopsis thaliana GN=At5g2325...	317.0	[0..1]	[329..1]
gi\|88798686, gi\|... - gi\|88798686\|ref\|ZP_01114269.1\| succinyl-CoA synthetase alpha subunit [Reinekea sp. MED297], gi\|88778...	314.0	[0..33]	[325..1]
gi\|76156042 - gi\|76156042\|gb\|AAX27280.2\| SJCHGC04909 protein [Schistosoma japonicum]	313.0	[0..24]	[331..13]
gi\|49610829, gi\|... - gi\|50120303\|ref\|YP_049470.1\| succinyl-CoA synthetase subunit alpha [Pectobacterium atrosepticum SCRI...	312.0	[0..33]	[328..1]
gi\|93004946, gi\|... - gi\|93004946\|ref\|YP_579383.1\| succinyl-CoA synthetase, alpha subunit [Psychrobacter cryohalolentis K5...	312.0	[0..33]	[325..1]
gi\|54296569, gi\|... - gi\|54296569\|ref\|YP_122938.1\| succinyl-CoA synthetase, alpha subunit [Legionella pneumophila str. Par... gi\|53753362, gi\|... - gi\|54293530\|ref\|YP_125945.1\| succinyl-CoA synthetase, alpha subunit [Legionella pneumophila str. Len... gi\|148282582, gi... - gi\|148360809\|ref\|YP_001252016.1\| succinyl CoA synthetase alpha chain [Legionella pneumophila str. Co...	312.0	[0..33]	[325..1]

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Predicted Domain #1

Region A:
Residues: [1-331]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFKTQTTLLT SLRRFSSSSQ LKNSKSLYEQ TIPNLMINSD TKVIFQGFTG KQGTFHAQHA  60
   61 MDYGTKVVGG TNPKKAGTTH LGKPVFGTIE EAMKETKADA SAVFVPPPLA AGAIEEAIAA 120
  121 EVPLIVAITE GIPQHDMLRV SDILKTQSKS RLVGPNCPGI IRPGQCKIGI MPSHIHKPGC 180
  181 IGIVSRSGTL TYEAVNQTTQ TDLGQSLVIG IGGDPFPGTN FIDALKLFLD DPNTQGIILI 240
  241 GEIGGSAEED AAEFIRAANA SRSTPKPVVS FIAGATAPKG RRMGHAGAIV AGGKGTAAAK 300
  301 FEALEAAGVR ISRSPATLGS LIVEELNKLK H

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	82.0
Match:	1jkjA
Description:	Succinyl-CoA synthetase, alpha-chain, N-terminal (CoA-binding) domain; Succinyl-CoA synthetase, alpha-chain, C-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
succinate-CoA ligase activity	11.5979130191209	bayes_pls_golite062009
succinate-CoA ligase (GDP-forming) activity	10.9659410855563	bayes_pls_golite062009
CoA-ligase activity	10.4192804448897	bayes_pls_golite062009
acid-thiol ligase activity	10.243481928473	bayes_pls_golite062009
ligase activity, forming carbon-sulfur bonds	9.48706872092269	bayes_pls_golite062009
succinate-CoA ligase (ADP-forming) activity	9.35325976720833	bayes_pls_golite062009
malate dehydrogenase activity	4.38786524125089	bayes_pls_golite062009
oxidoreductase activity	3.09625241707629	bayes_pls_golite062009
transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer	3.07329302783164	bayes_pls_golite062009
ligase activity	2.30626698552338	bayes_pls_golite062009
catalytic activity	1.90735517755117	bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor	1.70038641098437	bayes_pls_golite062009
oxidoreductase activity, acting on CH-OH group of donors	1.65338499044318	bayes_pls_golite062009
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	1.47309297191111	bayes_pls_golite062009
malic enzyme activity	1.2147813077436	bayes_pls_golite062009
transferase activity, transferring acyl groups	1.15639517822408	bayes_pls_golite062009
L-malate dehydrogenase activity	1.02646414923682	bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH	0.99118526697655	bayes_pls_golite062009
ATP citrate synthase activity	0.917482134347073	bayes_pls_golite062009
monovalent inorganic cation transmembrane transporter activity	0.576163737662951	bayes_pls_golite062009
malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+) activity	0.120195861875768	bayes_pls_golite062009
inorganic cation transmembrane transporter activity	0.0913823272876781	bayes_pls_golite062009
alcohol dehydrogenase (NAD) activity	0.00644214957417527	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: