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Protein Overview: gi|123998707, gi...

General Information:
Name(s) found: gi|123998707 [NCBI NR]
gi|123984691 [NCBI NR]
Description(s) found:
Found 2 descriptions.
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  • gi|123998707|gb|ABM87009.1| POT1 protection of telomeres 1 homolog (S. pombe) [synthetic construct] [NCBI NR]
  • gi|123984691|gb|ABM83691.1| POT1 protection of telomeres 1 homolog (S. pombe) [synthetic construct] [NCBI NR]
    • Organism: synthetic construct
    Length: 634 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSLVPATNYI YTPLNQLKGG TIVNVYGVVK FFKPPYLSKG TDYCSVVTIV DQTNVKLTCL  60
   61 LFSGNYEALP IIYKNGDIVR FHRLKIQVYK KETQGITSSG FASLTFEGTL GAPIIPRTSS 120
  121 KYFNFTTEDH KMVEALRVWA STHMSPSWTL LKLCDVQPMQ YFDLTCQLLG KAEVDGASFL 180
  181 LKVWDGTRTP FPSWRVLIQD LVLEGDLSHI HRLQNLTIDI LVYDNHVHVA RSLKVGSFLR 240
  241 IYSLHTKLQS MNSENQTMLS LEFHLHGGTS YGRGIRVLPE SNSDVDQLKK DLESANLTAN 300
  301 QHSDVICQSE PDDSFPSSGS VSLYEVERCQ QLSATILTDH QYLERTPLCA ILKQKAPQQY 360
  361 RIRAKLRSYK PRRLFQSVKL HCPKCHLLQE VPHEGDLDII FQDGATKTPD VKLQNTSLYD 420
  421 SKIWTTKNQK GRKVAVHFVK NNGILPLSNE CLLLIEGGTL SEICKLSNKF NSVIPVRSGH 480
  481 EDLELLDLSA PFLIQGTIHH YGCKQCSSLR SIQNLNSLVD KTSWIPSSVA EALGIVPLQY 540
  541 VFVMTFTLDD GTGVLEAYLM DSDKFFQIPA SEVLMDDDLQ KSVDMIMDMF CPPGIKIDAY 600
  601 PWLECFIKSY NVTNGTDNQI CYQIFDTTVA EDVI

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..332] PSI-BLAST 124.0 Crystal structure of human POT1 bound to telomeric single-stranded DNA (TTAGGGTTAG)
    2 View Details [333..504] deduced N/A No confident structure predictions are available.
    3 View Details [505..634] MSA 1.011926 View MSA. No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • telomerase inhibitor activity
    		•  8.08322438894165 bayes_pls_golite062009
  • single-stranded telomeric DNA binding
    		•  7.13197590913268 bayes_pls_golite062009
  • telomeric DNA binding
    		•  7.07761964836826 bayes_pls_golite062009
  • DEAD/H-box RNA helicase binding
    		•  4.55461999169159 bayes_pls_golite062009
  • nucleic acid binding
    		•  3.99127970564994 bayes_pls_golite062009
  • DNA binding
    		•  3.53568546959418 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  3.53214384646348 bayes_pls_golite062009
  • single-stranded DNA binding
    		•  3.49337353583487 bayes_pls_golite062009
  • binding
    		•  2.83465364476231 bayes_pls_golite062009
  • structural constituent of ribosome
    		•  2.13063800565247 bayes_pls_golite062009
  • structural molecule activity
    		•  1.9177190829469 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.84350127337404 bayes_pls_golite062009
  • protein binding
    		•  1.20309946451799 bayes_pls_golite062009
  • DNA helicase activity
    		•  1.12203697857261 bayes_pls_golite062009
  • transcription repressor activity
    		•  1.11836126147719 bayes_pls_golite062009
  • transcription activator activity
    		•  1.09079153283893 bayes_pls_golite062009
  • nucleotidyltransferase activity
    		•  0.961606389385315 bayes_pls_golite062009
  • transcription factor activity
    		•  0.952569279670437 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  0.85691075793641 bayes_pls_golite062009
  • RNA polymerase activity
    		•  0.79554655100991 bayes_pls_golite062009
  • DNA-directed RNA polymerase activity
    		•  0.79554655100991 bayes_pls_golite062009
  • DNA-dependent ATPase activity
    		•  0.638831894247026 bayes_pls_golite062009
  • ribonuclease activity
    		•  0.62994126331969 bayes_pls_golite062009
  • nuclease activity
    		•  0.57381531077345 bayes_pls_golite062009
  • translation regulator activity
    		•  0.515576958825022 bayes_pls_golite062009
  • translation factor activity, nucleic acid binding
    		•  0.468402630523277 bayes_pls_golite062009
  • double-stranded DNA binding
    		•  0.378383789953688 bayes_pls_golite062009
  • exonuclease activity
    		•  0.28313884527829 bayes_pls_golite062009
  • translation initiation factor activity
    		•  0.2080607201312 bayes_pls_golite062009
  • four-way junction helicase activity
    		•  0.13147110156029 bayes_pls_golite062009
  • ATP-dependent DNA helicase activity
    		•  0.0179535526984695 bayes_pls_golite062009
  • helicase activity
    		•  0.0121541775159524 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.94

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle