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Protein Overview: FMP42

General Information:
Name(s) found: FMP42 / YMR221C [SGD]
Description(s) found:
Found 24 descriptions.
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  • Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; physical interaction with Atg27p suggests a possible role in autophagy [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 504 amino acids

    Gene Ontology:
    Cellular Component: mitochondrion [IDALink to PubMed articleLink to PubMed article]
    fungal-type vacuole [IDALink to PubMed article]
    Biological Process: biological_process [ND]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTSTRTLRYA QVACACIWCL FSAGIIFGFA ALKPILISEG VYHELCDPKD GDRLLCTAQD  60
   61 LKLNFIFALS ATVTNIMALP VGKILDMYGP RVCGIIGSCL LFLASGNFIS AKHLVSLWDP 120
  121 YLVGYTLLAV AGPFVFISCF QLANSFPQRS GTVLALLTGS FDSSSALFLL YRLLYQNWFP 180
  181 TLNVSRFFTL YLIVPVFILA CQLTIMPHSS YKTVNHIAKI AVEGLDENGR LIEGDTGSGI 240
  241 IPDEQERQSL IAIEREEDSI PSRPQRRKSV LETYVEDKLQ KKSGGIFGVL HGKSAYEQIK 300
  301 SPWFYLMLLF ALVAMLRINY FIATVRTQEE YLLNDPDLAL KLNSIFDMLL PLGGAVSIPF 360
  361 IGLLLDHTDT LSTLTILFTT STAIGVFGLI PNSFTWNLIG IVLLVVYRPF YYTVVSDYSS 420
  421 KVFGFDTFGT VYGLLSCICG IFNMSQNLLD KWTHTTFNMN PFPINLTLVI LTVVFSLTLT 480
  481 FYIRSQILPK PVNERGLSSN YQTI

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run MLP2 #32 Asynchronous Prep-No Phosphopeptide enrichment Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data FMP42 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..211] MSA 10.027995 View MSA. No confident structure predictions are available.
    2 View Details [212..282] deduced N/A No confident structure predictions are available.
    3 View Details [283..504] MSA 1.009939 View MSA. No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • transporter activity
    		•  3.82096685159505 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  3.34396155292818 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  3.07161916881404 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  3.00564985710417 bayes_pls_golite062009
  • organic acid transmembrane transporter activity
    		•  2.05049771748124 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  1.75140121218978 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  1.46819549608723 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  1.34985844043603 bayes_pls_golite062009
  • binding
    		•  1.02703439347949 bayes_pls_golite062009
  • secondary active transmembrane transporter activity
    		•  0.869150152038001 bayes_pls_golite062009
  • polyol transmembrane transporter activity
    		•  0.339747214378126 bayes_pls_golite062009
  • alcohol transmembrane transporter activity
    		•  0.339747214378126 bayes_pls_golite062009
  • symporter activity
    		•  0.327558013224678 bayes_pls_golite062009
  • solute:cation symporter activity
    		•  0.327558013224678 bayes_pls_golite062009
  • glycerol transmembrane transporter activity
    		•  0.222664452597504 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle