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View Structure Prediction Details

Protein: FMP42
Organism: Saccharomyces cerevisiae
Length: 504 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FMP42.

Description E-value Query
Range
Subject
Range
gi|190408447 - gi|190408447|gb|EDV11712.1| conserved hypothetical protein [Saccharomyces cerevisiae RM11-1a]
FMP42_YEAST - Protein FMP42 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=FMP42 PE=1 SV=1
FMP42 - Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purifi...
0.0 [1..504] [1..504]
gi|12847527 - gi|12847527|dbj|BAB27605.1| unnamed protein product [Mus musculus]
0.0 [8..465] [102..608]
SLC43A1 - solute carrier family 43, member 1
0.0 [8..465] [12..513]
gi|25320111 - pir||H83965 hypothetical protein BH2528 [imported] - Bacillus halodurans (strain C-125)
gi|15615091, gi|... - gi|15615091|ref|NP_243394.1| hypothetical protein BH2528 [Bacillus halodurans C-125], gi|10175148|db...
1.0E-29 [64..209] [46..190]
gi|6980007 - gi|6980007|gb|AAF34694.1|AF222906_4 Ydl054p [Candida albicans]
2.0E-28 [61..190] [62..194]

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Predicted Domain #1
Region A:
Residues: [1-211]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTSTRTLRYA QVACACIWCL FSAGIIFGFA ALKPILISEG VYHELCDPKD GDRLLCTAQD  60
   61 LKLNFIFALS ATVTNIMALP VGKILDMYGP RVCGIIGSCL LFLASGNFIS AKHLVSLWDP 120
  121 YLVGYTLLAV AGPFVFISCF QLANSFPQRS GTVLALLTGS FDSSSALFLL YRLLYQNWFP 180
  181 TLNVSRFFTL YLIVPVFILA CQLTIMPHSS Y

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted functions:

Term Confidence Notes
transporter activity 3.82096685159505 bayes_pls_golite062009
transmembrane transporter activity 3.34396155292818 bayes_pls_golite062009
substrate-specific transporter activity 3.07161916881404 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 3.00564985710417 bayes_pls_golite062009
organic acid transmembrane transporter activity 2.05049771748124 bayes_pls_golite062009
ion transmembrane transporter activity 1.75140121218978 bayes_pls_golite062009
active transmembrane transporter activity 1.46819549608723 bayes_pls_golite062009
cation transmembrane transporter activity 1.34985844043603 bayes_pls_golite062009
binding 1.02703439347949 bayes_pls_golite062009
secondary active transmembrane transporter activity 0.869150152038001 bayes_pls_golite062009
polyol transmembrane transporter activity 0.339747214378126 bayes_pls_golite062009
alcohol transmembrane transporter activity 0.339747214378126 bayes_pls_golite062009
symporter activity 0.327558013224678 bayes_pls_golite062009
solute:cation symporter activity 0.327558013224678 bayes_pls_golite062009
glycerol transmembrane transporter activity 0.222664452597504 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [212-282]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KTVNHIAKIA VEGLDENGRL IEGDTGSGII PDEQERQSLI AIEREEDSIP SRPQRRKSVL  60
   61 ETYVEDKLQK K

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [283-504]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SGGIFGVLHG KSAYEQIKSP WFYLMLLFAL VAMLRINYFI ATVRTQEEYL LNDPDLALKL  60
   61 NSIFDMLLPL GGAVSIPFIG LLLDHTDTLS TLTILFTTST AIGVFGLIPN SFTWNLIGIV 120
  121 LLVVYRPFYY TVVSDYSSKV FGFDTFGTVY GLLSCICGIF NMSQNLLDKW THTTFNMNPF 180
  181 PINLTLVILT VVFSLTLTFY IRSQILPKPV NERGLSSNYQ TI

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle