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Protein Overview: TRS120

General Information:
Name(s) found: TRS120 / YDR407C [SGD]
Description(s) found:
Found 29 descriptions.
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  • One of 10 subunits of the transport protein particle (TRAPP) complex of the cis-Golgi which mediates vesicle docking and fusion; involved in endoplasmic reticulum (ER) to Golgi membrane traffic [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 1289 amino acids

    Gene Ontology:
    Cellular Component: TRAPP complex [IDALink to PubMed article]
    Biological Process: ER to Golgi vesicle-mediated transport [IMPLink to PubMed article]
    Molecular Function: Rab guanyl-nucleotide exchange factor activity [IMPLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNILKHFPSY VGPSKIRTLV IPIGHWTRKE FNNAVQKLSE FNEIHLSDVT PIDSPIFTPQ  60
   61 GFPHGKLFFD FLTIDHDDAL ELFLYDFEPF RKTFVIIGLV NDYSDPLTNL NFMKEKYPTL 120
  121 ISPNLVYASS TPTKELEQTI DTMENVFASS PDMQKNIETI MCDIARNFLT ALNSYYSSYK 180
  181 HVTLRSPGAI GGNAVLKTTL IRQNSYTSSS SSTPMSAVQS SVSSSSKAGS VTTASKRLSS 240
  241 FEMTTNSLKR SASLKLATTL STSENRSQQK SLGRQMKILG NFQLLAGRYV DALNSFVDAI 300
  301 TTLYKVRDYL WLGSALDGIS ICFLLLSYLG LSYQIPQIVS LICPVEKLNF ESSSTGISPV 360
  361 DSNSKATAST TASSTPRNSI SIAAMQSPRN SIMSLSAPAL NIDVENINLP LLIKCISDKV 420
  421 LYYYDLSLMH NSEYAPQVVY CEFLLKTLTF MTSCYKSSEF SKDVLDNIVK NQHRALSDIP 480
  481 NSPMFPRFEV YFYSNKLFEL QLKEMQVEAQ IKIYSTMAEV YRLLGYKRKQ LFVLRLLMVA 540
  541 LLATPNKIAW HPDYRTLIDT IIELLNINES EAKINVDDPS QSTWLILQKK ILQLCIKVSR 600
  601 KINDFEYVAK FSSILITKYT HLLNQSEQDA LFKEYIQPSI TNESITSYWD PFILREVVIN 660
  661 RILDSDPTSN EIPLESDVSS LESLENRQKT QDINPQEVFN PFKRVQPTSF VSNNSTKVPI 720
  721 LVFLVGDKAE FTCRVQNPFK FDFTINDIQL DEEISEFCEI DRKAVSYSGP YNVKAESIRS 780
  781 ITLPLIIKKP TYKKIYEISC LKISILKLPL QKFDIINDSR RSNPVEEEAE YSKCIYGKLK 840
  841 IKILPEQPQL ELLSTSKMTR NSWMMLDGTK TDFHITVRNK SLSCAINHIK IIPMNNIEQM 900
  901 LKPDYWKKMP PDDLYIMEKQ LDWLSKSCVR IIKLPTVIKP NETITFDLEL DNTAVPFNFT 960
  961 GFDLLIEYGM SATDESCIYL KKLSIPYEVT LRRTIEVPSM DIIPLNELFS SQVENVDWIE1020
 1021 YVMSKIRAES NLHSRDFILL LLDFRNSWID GIKLNVQFED FTSNEYHVEA SHTSRIIVPI1080
 1081 KKIDYKKYNF ENTPIPRIYP GRQFIQSGLN EEQTIEMRQK FWCREHIISK LKCNWKLTTD1140
 1141 QSVTGSVDFN KFIEKFDHKM VYTIYPGRLF YGVQLLLDEP KVKVGEIINL KIITEPTSTC1200
 1201 RRKQNSTVNF LDIVIFDSKT SKILPRSNRR ILYNGSLTKP ISTTKVSEIN LEIIPIEKGR1260
 1261 YEFSVCISKS NNQDGIIQFD SENVILSVI

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Riffle et al. (2010) (Unpublished Data) BET3 BET5 GSG1 KRE11 TRS120 TRS130 TRS20 TRS23 TRS31 TRS33
    View Details (MIPS) Mewes HW, et al. (2004) BET3 BET5 GSG1 KRE11 TRS120 TRS130 TRS20 TRS23 TRS31 TRS33
    View Details Krogan NJ, et al. (2006) TRS120 TRS23 TRS31 TRS33
    View Details Gavin AC, et al. (2006) BET3 BET5 GSG1 KRE11 TRS120 TRS130 TRS20 TRS23 TRS31 TRS33
    View Details Gavin AC, et al. (2002) BET3 BET5 FKS1 GSG1 KRE11 RVB2 SKN1 TRS120 TRS130 TRS20 TRS23 TRS31 TRS33
    View Details Ho Y, et al. (2002) GYP6 TRS120 TRS130
    View Details Qiu et al. (2008) BET3 BET5 GSG1 KRE11 SED5 TRS120 TRS130 TRS20 TRS23 TRS31 TRS33 YOS1

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run CEP3 sample cbf3 from feb 2005 Sandall S, et all (2006)
    View Run RPA135 No Comments Schneider, DA, et al. (2006)
    View Run ZDS1 Sample 2- cpn2 from june 2005 McCusker D, et al (2007)
    View Run ZDS1 Sample 3 - cpn + atp, from june 2005 McCusker D, et al (2007)
    View Run BOI1 Sample boi1 with gst from october 2005 McCusker D, et al (2007)
    View Run MLP2 #12 Mitotic Prep1-TiO2 Flowthrough Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data TRS120 and CHC1 Huh WK, et al. (2003)
    View Data TRS120 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..204] deduced N/A No confident structure predictions are available.
    2 View Details [205..992] MSA 2.009822 View MSA. No confident structure predictions are available.
    3 View Details [993..1289] deduced N/A No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.47

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle