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Protein Overview: TRS20

General Information:
Name(s) found: TRS20 / YBR254C [SGD]
Description(s) found:
Found 28 descriptions.
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  • One of 10 subunits of the transport protein particle (TRAPP) complex of the cis-Golgi which mediates vesicle docking and fusion; mutations in the human homolog cause the spondyloepiphyseal dysplasia tarda (SEDL) disorder [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 175 amino acids

    Gene Ontology:
    Cellular Component: TRAPP complex [IDALink to PubMed article]
    Biological Process: ER to Golgi vesicle-mediated transport [IMPLink to PubMed article]
    Molecular Function: Ras guanyl-nucleotide exchange factor activity [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPQYFAIIGK KDNPVYEIEF TNAENPQGFP QDLKELNPFI LHASLDIVED LQWQINPTSQ  60
   61 LNGNGGNGSN GGGGFLRSRA VNNTDNCYLG KVDHFYGLAI TAYISYSGMK FVMIHGNSAN 120
  121 SSVVIDDNNM RSFYQEVHEL YVKTLMNPFY KITDPIRSPA FDSRVRTLAR KHLSK

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Riffle et al. (2010) (Unpublished Data) BET3 BET5 GSG1 KRE11 TRS120 TRS130 TRS20 TRS23 TRS31 TRS33
    View Details (MIPS) Mewes HW, et al. (2004) BET3 BET5 GSG1 KRE11 TRS120 TRS130 TRS20 TRS23 TRS31 TRS33
    View Details Krogan NJ, et al. (2006) BET3 GYP6 TRS20
    View Details Gavin AC, et al. (2006) BET3 BET5 GSG1 KRE11 TRS120 TRS130 TRS20 TRS23 TRS31 TRS33
    View Details Gavin AC, et al. (2002) BET3 BET5 FKS1 GSG1 KRE11 RVB2 SKN1 TRS120 TRS130 TRS20 TRS23 TRS31 TRS33
    View Details Qiu et al. (2008) BET3 BET5 GSG1 KRE11 TRS120 TRS130 TRS20 TRS23 TRS31 TRS33

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data TRS20 and CHC1 Huh WK, et al. (2003)
    View Data TRS20 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..175] PSI-BLAST 39.0 No description for 2j3wA was found.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle