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Protein Overview: PET112

General Information:
Name(s) found: PET112 / YBL080C [SGD]
Description(s) found:
Found 21 descriptions.
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  • Subunit of the trimeric GatFAB AmidoTransferase(AdT) complex; involved in the formation of Q-tRNAQ; mutation is functionally complemented by the bacterial GatB ortholog [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 541 amino acids

    Gene Ontology:
    Cellular Component: mitochondrion [IDALink to PubMed articleLink to PubMed article][IGILink to PubMed article]
    Biological Process: aerobic respiration [IMPLink to PubMed article]
    mitochondrion organization [IMPLink to PubMed article]
    translation [IMPLink to PubMed article]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLRLARFYSL ARTKAIHSHG APFRPEYALK CGLEIHTQLN TKNKLFSQST NSATSLVDAP  60
   61 NHHTSYYDIA LPGTQPVLNL EAILFAMKLS LALGSQVNSI SQFDRKHYFY GDQPQGYQLT 120
  121 QHYRPFARGG KINLSKELDD IDESAKEIGI LQLQIEQDTG KSHYTETDKD VITLVDLNRS 180
  181 NVPLIELVTK PDFSDIKQVR AFIKKYQNLV RHLHISSGDL ETGAMRVDVN LSINEYARVE 240
  241 LKNLPNTSSI INAIKYEYQR QVELISVGDT SSLMEPETRG WTGSSTVKLR SKETTIDYRY 300
  301 MPDPELPYIN LAPDVISGVR GLMPQLPDDI MRILMKKPYQ LSLKDAKILT YNSNQNDMYN 360
  361 HEALRSYYLD TFREFSKLAG ERSNAKLPTN WIIHEFLGDL NKLQIPLAKA KEILAPPVFA 420
  421 QFLKLLHEEV ISATSGKMLL FHILENFEQS NCQDLSIPDF SKLIEKFELH AINQVDPQEL 480
  481 MDLCNDVIAQ HTDDTFIRNL VTGKKKSSLK FLIGQGMRRS QGRIKANEFE KKFKEILNIQ 540
  541 W

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details (MIPS) Mewes HW, et al. (2004) AEP1 AEP2 CBP6 CBS1 CBS2 MSS51 PET111 PET112 PET122 PET309 PET494 PET54 SUV3
    View Details Ho Y, et al. (2002) CDC33 PET112 PRB1 SNF1 TFP1 YEL023C YGR016W YPK2
    View Details Qiu et al. (2008) PET112 PET309

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen MIG1 PET112 1 Unpublished Fields Lab Data
    View Screen RAD51 PET112 1 Unpublished Fields Lab Data
    View Screen UBP6 PET112 1 Unpublished Fields Lab Data

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data PET112 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..271] Pfam 135.229148 PET112 family, N terminal region No confident structure predictions are available.
    2 View Details [272..363] ORFEUS 7.06 Annexin VI
    3 View Details [364..541] ORFEUS 7.06 Annexin VI

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity
    		•  6.94703732461209 bayes_pls_golite062009
  • ligase activity
    		•  5.28014676041088 bayes_pls_golite062009
  • catalytic activity
    		•  1.08973967683802 bayes_pls_golite062009
  • binding
    		•  1.0468360119595 bayes_pls_golite062009
  • ammonia ligase activity
    		•  0.978763138251862 bayes_pls_golite062009
  • ligase activity, forming carbon-nitrogen bonds
    		•  0.789800177023595 bayes_pls_golite062009
  • acid-ammonia (or amide) ligase activity
    		•  0.632807059205458 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.545649763280687 bayes_pls_golite062009
  • protein binding
    		•  0.440356087696859 bayes_pls_golite062009
  • kinase activity
    		•  0.21984983699175 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.132389278472779 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.95

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle