YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Catalysis of the transfer of the amide nitrogen of glutamine to a variety of substrates. GATases catalyze two separate reactions at two active sites, which are located either on a single polypeptide chain or on different subunits. In the glutaminase reaction, glutamine is hydrolyzed to glutamate and ammonia, which is added to an acceptor substrate in the synthase reaction. Catalysis of the reaction: L-glutamine + glutamyl-tRNA(Gln) + ATP = L-glutamate + glutaminyl-tRNA(Gln) + phosphate + ADP. Catalysis of the ligation of two substances via a carbon-nitrogen bond with concomitant breakage of a diphosphate linkage, usually in a nucleoside triphosphate.

View Gene Ontology (GO) Term

GO TERM SUMMARY

Name: glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity
Acc: GO:0050567
Aspect: Molecular Function
Desc: Catalysis of the reaction: L-glutamine + glutamyl-tRNA(Gln) + ATP = L-glutamate + glutaminyl-tRNA(Gln) + phosphate + ADP.
Synonyms:
  • Glu-tRNAGln:L-glutamine amido-ligase (ADP-forming)
  • Glu-AdT activity
  • glutamyl-tRNAGln amidotransferase activity
  • GO:0008264
  • Glu-tRNAGln amidotransferase activity
  • glutamyl-tRNA(Gln) amidotransferase activity
  • GO:0017068
  • glutamyl-tRNAGln:L-glutamine amido-ligase (ADP-forming)
  • glutaminyl-tRNA synthase (glutamine-hydrolysing)
  • glu-tRNA(gln) amidotransferase activity
Proteins in PDR annotated with:
   This term: 14 [Search]
   Term or descendants: 14 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0050567 - glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity (interactive image map)

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle