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Catalysis of the reaction: ATP + diphthine + NH3 = ADP + phosphate + diphthamide. Catalysis of the reaction: ATP + L-glutamate + NH3 = ADP + phosphate + L-glutamine. Catalysis of the reaction: ATP + L-aspartate + NH3 = AMP + diphosphate + L-asparagine. Catalysis of the ligation of an acid to ammonia (NH3) or an amide via a carbon-nitrogen bond with concomitant breakage of a diphosphate linkage, usually in a nucleoside triphosphate. Catalysis of the ligation of two substances via a carbon-nitrogen bond with concomitant breakage of a diphosphate linkage, usually in a nucleoside triphosphate. Catalysis of the ligation of ammonia (NH3) to another substance via a carbon-nitrogen bond with concomitant breakage of a diphosphate linkage, usually in a nucleoside triphosphate.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: ammonia ligase activity
Acc: GO:0016211
Aspect: Molecular Function
Desc: Catalysis of the ligation of ammonia (NH3) to another substance via a carbon-nitrogen bond with concomitant breakage of a diphosphate linkage, usually in a nucleoside triphosphate.
Proteins in PDR annotated with:
   This term: 3 [Search]
   Term or descendants: 53 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0016211 - ammonia ligase activity (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle