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Protein Overview: abts-2

General Information:
Name(s) found: abts-2 / CE40613 [WormBase]
Description(s) found:
Found 14 descriptions.
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  • WBGene00009929 locus:abts-2 status:Confirmed UniProt:G5EGB9 protein_id:CAA91473.4 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 737 amino acids

    Gene Ontology:
    Cellular Component: membrane [IEALink to PubMed article]
    integral to membrane [IEALink to PubMed article]
    basolateral plasma membrane [IDALink to PubMed article]
    Biological Process: anion transport [IEALink to PubMed article]
    Molecular Function: anion exchanger activity [IEALink to PubMed article]
    inorganic anion exchanger activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPELLCRTER VEHARNFKTE VRGLMDVDHL IERACIHRNM NHSHIHTILL SLFSDLSSRF  60
   61 PQEKFDLALF KNAVFSVSDR DSRAPRLHHK LQSYSGTDFF DVNQTWIVTY AQLDGLKQSH 120
  121 MALATLEDAT NLGLEMEEAR TVVLILSPSY EKHTKSAAEI ARTFATLLMN DTLRQSVNDA 180
  181 ADDDQLRDLL TEYAKGLSQQ LTIQVNGKPI ADDDDEYESK NSSFCPYYPF RGLVKDFKRR 240
  241 MANYKSDYLD GIKDRRSVSK VISTAVFLIF TILPTSIAYG MLNENNTNGA INVQKVVLGQ 300
  301 WIGSLLFGIF GGQQLLILST TAPLSIYIAV IYQVAQTNDW DFFQMYASVG IYAMGLLILA 360
  361 SVFQLASLMK FTTRSTEEIF SVFIALALII KAIMAIVHVY THGYLGCINN VAGDLCDPAE 420
  421 PLLFIFLLFG TTWLSMTIIS FRSSPYLSRW KRDLVSDYAL PIAVLVFSFI SFFGFSDVKK 480
  481 EQFQIFSRET DAFFVPFFNL PAEAQLPAVG LAIPLSILFF MDQLLVTNTV DNKDNKLKKG 540
  541 SAHHWDLLVV GVLNIGLSIF GLPWMHGALP SAYLHLKALS DVEDRLHNGY IQTVIVHVRE 600
  601 TRLATLIAHI IMIPIYFFLV PHITVFIPTS IFNGVFLFMA FSSLTGNEFW ERILLIFTEQ 660
  661 RAYPPTHYIR RVPQRVVHQF TIIEFIQLVI LVAIGFAQYH YVEMVFPIVI AAFIPFRHFF 720
  721 LPLFIRKQYL EAIDGQH

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..253] PSI-BLAST 31.69897 Erythrocite membrane Band 3
    2 View Details [254..443] MSA 3.819994 View MSA. No confident structure predictions are available.
    3 View Details [444..534] deduced N/A No confident structure predictions are available.
    4 View Details [535..627] MSA 2.812996 View MSA. No confident structure predictions are available.
    5 View Details [628..737] MSA 1.785987 View MSA. No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • anion transmembrane transporter activity
    		•  5.53342374278862 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  5.52089460336827 bayes_pls_golite062009
  • inorganic anion transmembrane transporter activity
    		•  5.05984221151516 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  4.53671418417138 bayes_pls_golite062009
  • transporter activity
    		•  3.71632554122909 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  3.65156575316092 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  3.6328272808612 bayes_pls_golite062009
  • bicarbonate transmembrane transporter activity
    		•  3.47798360646642 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  3.1367361209641 bayes_pls_golite062009
  • chloride transmembrane transporter activity
    		•  2.81610322933515 bayes_pls_golite062009
  • anion exchanger activity
    		•  2.81610322933515 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  2.69943173291914 bayes_pls_golite062009
  • sodium:bicarbonate symporter activity
    		•  2.55643394918259 bayes_pls_golite062009
  • anion:anion antiporter activity
    		•  2.28054946403665 bayes_pls_golite062009
  • secondary active transmembrane transporter activity
    		•  1.36491414637832 bayes_pls_golite062009
  • antiporter activity
    		•  1.16370853401172 bayes_pls_golite062009
  • binding
    		•  1.10848568469131 bayes_pls_golite062009
  • protein binding
    		•  0.324874109063796 bayes_pls_golite062009
  • carbohydrate transmembrane transporter activity
    		•  0.0141334718769964 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.
    4 No functions predicted.
    5 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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