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View Structure Prediction Details

Protein: abts-2
Organism: Caenorhabditis elegans
Length: 737 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for abts-2.

Description E-value Query
Range
Subject
Range
gi|109099955 - gi|109099955|ref|XP_001093637.1| PREDICTED: similar to solute carrier family 4, sodium bicarbonate t...
gi|114581506 - gi|114581506|ref|XP_515857.2| PREDICTED: similar to sodium-driven chloride bicarbonate exchanger rb2...
497.0 [0..8] [734..155]

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Predicted Domain #1
Region A:
Residues: [1-253]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPELLCRTER VEHARNFKTE VRGLMDVDHL IERACIHRNM NHSHIHTILL SLFSDLSSRF  60
   61 PQEKFDLALF KNAVFSVSDR DSRAPRLHHK LQSYSGTDFF DVNQTWIVTY AQLDGLKQSH 120
  121 MALATLEDAT NLGLEMEEAR TVVLILSPSY EKHTKSAAEI ARTFATLLMN DTLRQSVNDA 180
  181 ADDDQLRDLL TEYAKGLSQQ LTIQVNGKPI ADDDDEYESK NSSFCPYYPF RGLVKDFKRR 240
  241 MANYKSDYLD GIK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 31.69897
Match: 1hynP
Description: Erythrocite membrane Band 3
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
anion transmembrane transporter activity 5.53342374278862 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 5.52089460336827 bayes_pls_golite062009
inorganic anion transmembrane transporter activity 5.05984221151516 bayes_pls_golite062009
ion transmembrane transporter activity 4.53671418417138 bayes_pls_golite062009
transporter activity 3.71632554122909 bayes_pls_golite062009
substrate-specific transporter activity 3.65156575316092 bayes_pls_golite062009
transmembrane transporter activity 3.6328272808612 bayes_pls_golite062009
bicarbonate transmembrane transporter activity 3.47798360646642 bayes_pls_golite062009
active transmembrane transporter activity 3.1367361209641 bayes_pls_golite062009
chloride transmembrane transporter activity 2.81610322933515 bayes_pls_golite062009
anion exchanger activity 2.81610322933515 bayes_pls_golite062009
cation transmembrane transporter activity 2.69943173291914 bayes_pls_golite062009
sodium:bicarbonate symporter activity 2.55643394918259 bayes_pls_golite062009
anion:anion antiporter activity 2.28054946403665 bayes_pls_golite062009
secondary active transmembrane transporter activity 1.36491414637832 bayes_pls_golite062009
antiporter activity 1.16370853401172 bayes_pls_golite062009
binding 1.10848568469131 bayes_pls_golite062009
protein binding 0.324874109063796 bayes_pls_golite062009
carbohydrate transmembrane transporter activity 0.0141334718769964 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [254-443]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DRRSVSKVIS TAVFLIFTIL PTSIAYGMLN ENNTNGAINV QKVVLGQWIG SLLFGIFGGQ  60
   61 QLLILSTTAP LSIYIAVIYQ VAQTNDWDFF QMYASVGIYA MGLLILASVF QLASLMKFTT 120
  121 RSTEEIFSVF IALALIIKAI MAIVHVYTHG YLGCINNVAG DLCDPAEPLL FIFLLFGTTW 180
  181 LSMTIISFRS 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [444-534]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SPYLSRWKRD LVSDYALPIA VLVFSFISFF GFSDVKKEQF QIFSRETDAF FVPFFNLPAE  60
   61 AQLPAVGLAI PLSILFFMDQ LLVTNTVDNK D

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [535-627]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NKLKKGSAHH WDLLVVGVLN IGLSIFGLPW MHGALPSAYL HLKALSDVED RLHNGYIQTV  60
   61 IVHVRETRLA TLIAHIIMIP IYFFLVPHIT VFI

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [628-737]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PTSIFNGVFL FMAFSSLTGN EFWERILLIF TEQRAYPPTH YIRRVPQRVV HQFTIIEFIQ  60
   61 LVILVAIGFA QYHYVEMVFP IVIAAFIPFR HFFLPLFIRK QYLEAIDGQH 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle